Human blood stem cells carry a lasting memory of inflammatory stress
TL;DR Summary
A Nature study identifies two human hematopoietic stem cell states after inflammatory stress: a quiescent baseline (LT‑HSC) and a durable inflammatory‑memory subset (HSC‑iM) that remains after recovery, transmits memory to immune progeny, and is linked to aging, COVID‑19 recovery, and clonal hematopoiesis.
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