Intranasal spray resets aging brain and sharpens memory

Texas A&M researchers report that a two-dose intranasal spray delivering extracellular vesicles with microRNAs reduced brain inflammation, recharged neuronal mitochondria, and noticeably improved memory in preclinical aging models, suggesting a noninvasive therapy for brain aging and dementia that bypasses the blood-brain barrier; the team has filed a US patent with backing from the National Institute on Aging.