Most sugar substitutes disrupt gut bacteria and trigger surprising drug interactions

TL;DR
A Cambridge study tested 39 sweeteners against 25 gut bacteria and found that roughly 75% affected at least one strain; mixing sweeteners with common compounds (caffeine, vanillin, and the antidepressant duloxetine) produced over 100 new interactions, some disruptive, suggesting sugar substitutes can alter the gut microbiome and interact with medications; the WHO notes non-sugar sweeteners show no proven long-term weight‑loss benefits.
Topics:healthscience#artificial-sweeteners#drug-interactions#duloxetine#gut-microbiome#science#sugar-substitutes
- Scientists Tested 39 Artificial Sweeteners and Found Most Affected at Least One Gut Bacterium ZME Science
- Feinsinger column: Artificial sweeteners Post Independent
- 🧠 This sweetener could disrupt brain vascularity Techno-Science
- Sugar substitutes may do more harm than good Earth.com
- Diet soda could be harming your brain health: 62% thinking skills loss linked to artificial sweeteners ove The Economic Times
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