Workout-Driven Shield: How Exercise Tightens the Brain’s Barrier to Preserve Memory

TL;DR
UC San Francisco researchers show that exercise increases the liver enzyme GPLD1, which travels to brain blood vessels and removes TNAP from the blood-brain barrier. This restores barrier integrity and reduces leakiness and inflammation in aging mice, helping memory and cognitive performance, and suggesting new therapeutic avenues for aging and Alzheimer’s-related decline.
- Aging Makes the Brain Leaky but Exercise Fights Back SciTechDaily
- Scientists Find a Mechanism for How Exercise Protects the Brain UC San Francisco
- The exercise routine that scientists say can make your brain ‘measurably younger’ The Independent
- Exercise activates a liver enzyme that fixes brain vascular damage and improves memory. vocal.media
- Scientists reveal how exercise protects the brain from Alzheimer’s ScienceDaily
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