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Cepi

All articles tagged with #cepi

world20 hours ago•4 min saved

Global Push to Fast-Track Bundibugyo Ebola Vaccines Amid Insecurity

With no approved vaccine or treatment yet for the Bundibugyo Ebola strain spreading in the DRC and Uganda, about $60 million in emergency funding is aimed at accelerating vaccine candidates (IAVI's rVSV Bundibugyo and Oxford's ChAdOx1 Bundibugyo) and potential treatments (MBP134, Maftivimab, remdesivir), plus a preventive drug trial. Trials are hampered by security issues in the affected region, delaying site setup and testing. Timelines vary from a couple of months to seven–nine months before trials can begin, and operational realities may slow progress despite scientific readiness.

via The Guardian|

#bundibugyo #cepi #ebola

health3 days ago•10 min saved

Moderna lands $50M to push mRNA Ebola vaccine for Bundibugyo

CEPI pledged over $60 million to accelerate Bundibugyo ebolavirus vaccine development, including up to $50 million to Moderna for preclinical work and early-stage trials of an mRNA BDBV vaccine and to ramp up manufacturing for larger Phase 2/3 testing; other funds go to IAVI and the Oxford/Serum Institute effort. No licensed vaccines exist for Bundibugyo yet, and the current DRC outbreak has about 1,041 cases and 241 deaths as reported by the WHO.

via Ars Technica|

#bundibugyo-ebolavirus #cepi #health

health3 days ago•4 min saved

Vaccine sprint targets Bundibugyo Ebola amid rising outbreak

Three vaccines targeting Bundibugyo Ebola are in development by IAVI, Moderna, and Oxford as DR Congo and neighboring Uganda report rising cases; CEPI funds the efforts, but clinical trials won't start for months, raising fears the outbreak could reach the scale of West Africa's 2014-16 crisis.

via BBC|

#cepi #dr-congo #ebola