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Bundibugyo

All articles tagged with #bundibugyo

health6 days ago•6 min saved

New animal-to-human spillover sparks record Ebola outbreak in the DRC, study finds

A Nature Medicine study shows the current Ebola outbreak in the Democratic Republic of the Congo began with a new animal-to-human spillover of the Bundibugyo virus, then spread mainly through human-to-human transmission. With more than 4,400 cases and about 2,000 deaths, it’s the fastest-moving outbreak on record and could become the deadliest; there are no licensed vaccines or virus-specific treatments for this strain yet, though experimental options are in development. WHO projects the outbreak could peak within months and last up to a year under various scenarios, as efforts focus on expanded diagnostics, genomic sequencing, PPE for frontline workers, and cross-border measures amid challenges like health worker strikes and misinformation.

via Al Jazeera|

#bundibugyo #drc #ebola

health7 days ago•45 min saved

Fresh animal-to-human spillover tied to Congo-Uganda Ebola outbreak, study says

A Nature Medicine study analyzing samples from 22 patients finds a new Bundibugyo Ebola virus variant linked to a fresh animal-to-human spillover in the Congo-Uganda outbreak; the strain is genetically distinct from earlier Bundibugyo outbreaks, and Uganda cases are connected to the Congo event, though the exact animal source remains unidentified. There is no approved vaccine, but candidates are in development. The study highlights the value of broader testing and virus sequencing for early outbreak detection, as the outbreak has surpassed 2,000 deaths with about 4,381 confirmed cases to date.

via Yahoo|

#bundibugyo #congo #ebola

health7 days ago•7 min saved

Bundibugyo Ebola Outbreak in DRC Surpasses 2,000 Deaths, Yet US Risk Remains Low

The Bundibugyo strain of Ebola in eastern Congo has killed more than 2,000 people and infected over 4,300, with the strain being genetically distinct from the 2014 Zaire variant, limiting the effectiveness of existing therapies and vaccines. Despite the severity, the risk to Americans remains very low since transmission requires close contact with bodily fluids; researchers are pursuing new treatments and vaccines, including mRNA-based approaches, and international support is essential to containment.

via Fox News|

#bundibugyo #drc #ebola

world8 days ago•200 min saved

Congo's Ebola surge becomes fastest-growing on record, crossing 2,000 deaths

Congo’s Bundibugyo Ebola outbreak — the fastest-growing on record — has killed about 2,000 people (2,011 deaths among 4,381 confirmed cases) as it spreads across five eastern provinces near South Sudan, Uganda and Rwanda. It is the second-largest Ebola outbreak in history, with a case-fatality rate around 45.9% and no approved vaccines or treatments for Bundibugyo. The outbreak began earlier than officially declared (likely February) and responders face challenges from ongoing conflict, poor infrastructure, and misinformation, while early cases were sometimes misclassified as malaria or typhoid; vaccines are in clinical trials, and authorities have restricted gatherings to slow transmission.

via cnn.com|

#bundibugyo #congo #ebola

health9 days ago•3 min saved

DRC Ebola Outbreak Began Months Earlier Than Declared, WHO Finds

The Democratic Republic of Congo's Ebola outbreak—the fastest-growing on record—started in February, months before it was officially declared in mid-May. WHO sequencing suggests early cases were misattributed to malaria and typhoid. With 4,200 confirmed cases and at least 1,900 deaths, the Bundibugyo strain has no licensed vaccines or treatments, delaying response. WHO is pursuing Ervebo vaccine trials while Bundibugyo vaccines are in early development, amid challenges from strikes, conflict, misinformation, and displacement.

via Al Jazeera|

#bundibugyo #drc #ebola

world15 days ago•3 min saved

DRC Ebola toll tops 1,700 as WHO accelerates trials

The Democratic Republic of the Congo’s Ebola outbreak has killed 1,707 people and infected 3,802, with most cases in Ituri province. The Bundibugyo strain has no approved vaccines or treatments yet, but the WHO says trials of experimental therapies and vaccines are moving faster than in prior outbreaks. More than 17,000 contacts are being monitored, though the response is hampered by violence, mistrust, and funding gaps; healthcare workers are among those infected. Uganda has declared Ebola-free, and this outbreak is the second-largest and fastest-growing on record.

via Al Jazeera|

#bundibugyo #drc #ebola

world18 days ago•15 min saved

Eastern Congo Ebola toll climbs past 1,500 in fastest-spreading outbreak

Eastern Congo’s Ebola outbreak linked to the Bundibugyo virus has killed 1,521 people out of 3,442 cases, marking the fastest-growing surge as response efforts are hampered by backlogs, mistrust, and violence; Ituri province accounts for the vast majority of cases, with attacks on health facilities and limited vaccines/treatments complicating containment, while the WHO says global risk is low but Congo’s risk is very high and neighboring Uganda has declared itself Ebola-free.

via KSL.com|

#bundibugyo #congo #ebola

health18 days ago•7 min saved

DR Congo Confronts its Worst-Ever Ebola Outbreak Under Bundibugyo Strain

DR Congo is facing its largest Ebola outbreak on record, caused by the Bundibugyo strain, with 3,605 confirmed cases and 1,587 deaths (about 44% fatal) as of July 30, 2026, surpassing the 2018–2020 outbreak. No approved vaccine or treatment exists yet, though vaccines are in development in the UK and Singapore. The outbreak is intensifying, with the highest weekly totals (567 cases, 296 deaths) and is hampered by insecurity, displacement, and cross-border movement. The epicenter is Ituri Province, with spread to North and South Kivu and cases in Uganda; a few cases have been treated in Europe. WHO notes ongoing transmission and progress on vaccine development as trials proceed."

via BBC|

#bundibugyo #dr-congo #ebola

health20 days ago•3 min saved

DRC Ebola toll climbs past 1,500 as outbreak presses on amid conflict and vaccine gaps

DRC’s Ebola outbreak has 3,442 cases and 1,521 deaths (up about 50% in a week), with no vaccine for the Bundibugyo strain and containment hampered by ongoing conflict, limited access, reporting backlogs, and community mistrust; Ituri province accounts for about 90% of cases, while unsafe handling of bodies and attacks on health facilities fuel spread, though WHO says global risk remains low.

via Al Jazeera|

#africa-cdc #bundibugyo #dr-congo

health25 days ago•4 min saved

DRC Ebola Outbreak Surges to 1,309 Deaths as Spread Accelerates

Ebola deaths in the Democratic Republic of Congo have risen to at least 1,309 with confirmed cases near 2,973, marking a rapid surge in what experts call the fastest-spreading outbreak yet. The Bundibugyo variant, which has no approved vaccines, is driving the spread in a conflict-affected region, straining healthcare workers and facilities amid shortages and strikes. A rapidly developed experimental vaccine is in early trials, while officials urge immediate action and better access for responders to curb the crisis.

via Al Jazeera|

#bundibugyo #drc #ebola

health26 days ago•1 min saved

First human trial begins for Bundibugyo Ebola vaccine

An experimental vaccine targeting the Bundibugro strain of Ebola has entered its first-in-human phase to evaluate safety and immune response. It is one of four Bundibugro vaccines in development; existing Zaire-targeted vaccines do not work against Bundibugro. Oxford-led trials will be followed by a second small Uganda study and a larger efficacy trial in DR Congo. The Serum Institute has produced 600,000 doses if trials succeed. The DR Congo outbreak has over 2,500 confirmed cases and about 1,000 deaths.

via BBC|

#bundibugyo #clinical-trial #dr-congo

world27 days ago•14 min saved

Toll climbs as Congo's Ebola outbreak faces violence and shortages

Ebola has killed 1,033 people in the Democratic Republic of Congo, part of its 17th outbreak, with 2,536 confirmed cases. The Bundibugyo strain, which has no approved vaccine, is spreading amid insecurity in eastern Congo, attacks on clinics, and shortages of basic supplies, hindering containment. Some misinformation and burial restrictions compound challenges, while the outbreak has reached neighboring Uganda with relatively few confirmed cases.

via KSL.com|

#bundibugyo #congo #ebola

health28 days ago•3 min saved

Ebola toll in DR Congo climbs toward 1,000 as Bundibugyo outbreak accelerates

DR Congo’s Bundibugyo Ebola outbreak has killed 999 people in the DRC and 2 in Uganda, with 2,473 cases and 737 patients in isolation; declared in May in Ituri, the outbreak is spreading faster than any prior Ebola event, and there is no approved vaccine or treatment for this strain, prompting urgent calls for a stepped-up global response from WHO and Africa CDC.

via Al Jazeera|

#bundibugyo #dr-congo #ebola

health1 month ago•5 min saved

UK launches first Ebola vaccine trial amid outbreak

Regulators in the UK have approved phase-one trials for an Ebola vaccine developed at Oxford, kicking off just eight weeks after an outbreak was declared in the Democratic Republic of Congo. The trial will recruit 50 healthy adults in the UK, with potential trials in Africa, and uses a chimpanzee adenovirus vector carrying a Bundibugyo Ebola gene. Cure/production is by Serum Institute of India. Researchers aim to assess safety and immune response in parallel with other Ebola vaccines, as there are no approved vaccines yet and three other candidates are in development.

via BBC|

#bundibugyo #clinical-trials #ebola

global-health1 month ago•6 min saved

Record-fast Ebola treatment trial kicks off in DRC as first patients enroll

The Partners trial in Ituri has enrolled its first patients to test remdesivir and MBP134 against Bundibugyo Ebola, aiming for 700–1,000 participants; started six weeks after the WHO declared a public health emergency, with hopes to reduce mortality despite frontline pay and supply challenges.

via The Guardian|

#bundibugyo #clinical-trial #drc