All articles tagged with #d serine
Researchers found that aging-linked decline of the brain protein Menin in the ventromedial hypothalamus triggers inflammation, memory and physical aging signs in mice. Restoring Menin reversed several aging features, and dietary D-serine supplementation improved cognition in older mice, suggesting a brain-centered mechanism for aging with potential human relevance—but no human trials yet and safety remains uncertain.
A new study in mice has identified a previously unknown trigger of aging in the brain's hypothalamus, involving the age-related reduction of a protein called menin. The study suggests that a reduction in menin in the hypothalamus results in neuroinflammation that may cause characteristics of aging. The authors of the study also determined that a loss of menin causes a reduction in levels of an enzyme required for the production of the neurotransmitter, the amino acid D-serine. The study proposes that supplements of menin and D-serine may be able to reverse aspects of aging in humans.