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D Serine

All articles tagged with #d serine

health-and-medicine16 days ago•12 min saved

Hypothalamic Menin Decline Linked to Aging; D-Serine Supplementation Boosts Mouse Memory

Researchers led by Lige Leng at Xiamen University found that declining levels of the protein Menin in the hypothalamus drive systemic aging and cognitive loss in mice. Restoring Menin reversed age-related physical and mental decline within 30 days. Additionally, supplementing with the amino acid D-serine improved memory in three weeks, though it did not restore bone or skin health. While promising, human trials remain limited and D-serine effects vary by biological context.

via Science Daily|

#aging-research #cognitive-decline #d-serine

science5 months ago•7 min saved

Brain aging switch: Menin loss reversed in mice

Researchers found that aging-linked decline of the brain protein Menin in the ventromedial hypothalamus triggers inflammation, memory and physical aging signs in mice. Restoring Menin reversed several aging features, and dietary D-serine supplementation improved cognition in older mice, suggesting a brain-centered mechanism for aging with potential human relevance—but no human trials yet and safety remains uncertain.

via ScienceDaily|

#aging #cognition #d-serine

health3 years ago•4 min saved

"Menin protein holds key to reversing aging, new study suggests"

A new study in mice has identified a previously unknown trigger of aging in the brain's hypothalamus, involving the age-related reduction of a protein called menin. The study suggests that a reduction in menin in the hypothalamus results in neuroinflammation that may cause characteristics of aging. The authors of the study also determined that a loss of menin causes a reduction in levels of an enzyme required for the production of the neurotransmitter, the amino acid D-serine. The study proposes that supplements of menin and D-serine may be able to reverse aspects of aging in humans.

via Medical News Today|

#aging #d-serine #health