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All articles tagged with #development

Stanford Study Reframes the Brain as Two Separate Neural Systems
science18 days ago

Stanford Study Reframes the Brain as Two Separate Neural Systems

Stanford researchers reveal the brain is built from two ancient neural systems that develop in parallel from separate progenitors—Otx2 for the forebrain/midbrain and Gbx2 for the hindbrain—whose distinct chromatin states are set early in development. This explains why hindbrain neurons have been hard to grow in the lab and enables deriving hindbrain neurons from pluripotent stem cells, offering a new model to study SMA and ALS. Evolutionary evidence across chickens, zebrafish, acorn worms, and even jellyfish suggests two ancient nervous systems were brought together to form the modern brain, with potential implications for regenerative therapies and weight regulation.

via ScienceDaily|
#brain#development#hindbrain
Stanford study reveals the brain has two separate origins during development
science19 days ago

Stanford study reveals the brain has two separate origins during development

Stanford researchers found the front and hindbrain arise from distinct cell groups with different genetic instructions during gastrulation, suggesting the brain is two separate organs that later fuse. The team also generated hindbrain motor neurons from stem cells, a breakthrough that could accelerate research and potential therapies for neurodegenerative diseases such as ALS and SMA.

via The Independent|
#als#brain#development
Small Significance Sparks Big Effort: Meaning Drives Motivation From Childhood
psychology28 days ago

Small Significance Sparks Big Effort: Meaning Drives Motivation From Childhood

A series of four experiments shows that even tiny, lasting meaning—like saving a child’s artwork in a box—can boost effort and persistence in both children (ages four to nine) and adults. Participants preferred outcomes that would endure and were more willing to tackle harder tasks when they believed their work mattered, indicating that the need for meaning may be a fundamental, early-developing driver of motivation with implications for education and everyday activities.

via PsyPost|
#children#development#meaning
Eagles defend four-QB roster as smart insurance and development bet
sports1 month ago

Eagles defend four-QB roster as smart insurance and development bet

Eagles GM Howie Roseman defended keeping four quarterbacks on the active roster, saying the position’s high value justifies insurance and long-term development after last year’s McCord experience. He highlighted IPP players Uar Bernard and Joshua Weru as worth preserving despite waiver risks, praised tight end E.J. Jenkins’ development, expressed respect for Zach Ertz, and noted no August trades while remaining confident in the receiver group and the rebuilt interior line as the team ramps up for the first four weeks with further evaluation possible before the trade deadline.

via Bleeding Green Nation|
#development#eagles#note-only-five-tags-requested-ensure-exactly-five-for-compatibility
Dolphins push youth-first rebuild with QB plan and roster reshuffle
sports1 month ago

Dolphins push youth-first rebuild with QB plan and roster reshuffle

Miami Dolphins GM Jon-Eric Sullivan outlined a youth-forward rebuild after eight cuts and seven waiver claims, reiterating a draft-and-develop approach and salary-cap discipline. He described Kyle McCord and Brady Cook as promising development quarterbacks to back Malik Willis, and explained why Quinn Ewers was moved on for a fresh start. The plan centers on developing a young core (Caleb Douglas, Chris Bell, Kevin Coleman, Malik Washington) and strong special teams (Ryan Miller), with Kadyn Proctor at left guard and a developing secondary, while staying selective with free agency and prioritizing weekly improvement.

via Miami Herald|
#development#dolphins#nfl
The Long Arm of Laughs: A One-Limb Stealth Game Slaps Its Way to PC
games1 month ago

The Long Arm of Laughs: A One-Limb Stealth Game Slaps Its Way to PC

Toot Games' My Arms Are Longer Now reimagines stealth as a 3D, joke-forward indie experience centered on a single extendable arm that steals and slaps its way through NPCs. The game emphasizes humor over puzzles, features more than 40 voiced characters, and uses a tube-like limb with forced perspective to preserve its illustrated style after a 2D prototype. It secured publishing with Jackbox Games and is planned for PC release in 2027.

via The Guardian|
#comedy#development#games
Proposed Bakersfield Costco Triggers Traffic and Crime Concerns From Neighbors
local1 month ago

Proposed Bakersfield Costco Triggers Traffic and Crime Concerns From Neighbors

Neighbors in Bakersfield’s Gossamer Grove are expressing worry over a proposed Costco, gas station, and multiple restaurants at Seventh Standard Road and Calloway Drive, fearing traffic congestion and crime. The developer touts a road overhaul—including a six-lane expansion on Seventh Standard, arterial upgrades on Calloway Drive, an added parkway, and five access points with new signals—promising these improvements will be completed before any opening.

via New York Post|
#bakersfield#costco#crime
Hillsborough doubts cast shadow over Rays stadium deal as funding shifts
local-politics1 month ago

Hillsborough doubts cast shadow over Rays stadium deal as funding shifts

Two Hillsborough County commissioners who previously backed the Rays stadium deal now question it, potentially upending the pact as the financing structure shifts: the city would lend $80 million and the Rays would borrow about $100 million, to be repaid with property‑tax revenues from a surrounding mixed‑use development. Commissioner Chris Boles says there’s no guaranteed county revenue and seeks written assurances on the development piece, while Commissioner Christine Miller questions the city’s share and warns of possible exposure (up to $380 million) after a related land‑use change stalled. With votes looming next week, the changing terms and political dynamics add new uncertainty to the deal.

via Tampa Bay Times|
#development#financing#hillsborough-county
HBO Max Passes on Milo Ventimiglia’s Cop Drama American Blue, Eyes New Buyer
television1 month ago

HBO Max Passes on Milo Ventimiglia’s Cop Drama American Blue, Eyes New Buyer

Deadline reports HBO Max is not moving forward with American Blue, a Milo Ventimiglia-led cop drama from Warner Bros. Television, and is shopping the project to other buyers. Written by Jeremy Carver and directed by David Ayer, the series follows Brian “Milk” Milkovich as he returns to Joliet, Illinois to save a beleaguered police force while seeking redemption, with a multi-episode format similar to the Pitt model and a large ensemble cast.

via Deadline|
#american-blue#development#hbo-max
13-Story Crown Heights Tower Sparks Debate Over Who It Will House
real-estate2 months ago

13-Story Crown Heights Tower Sparks Debate Over Who It Will House

COLlive reports plans for a 13-story, 94-unit mixed-use building at 767 East New York Avenue in Crown Heights, developed by Yonah Grunhut of Grun Group LLC, replacing the former 770 Auto shop. With average unit sizes around 561 square feet, residents worry the project may add many small apartments that aren’t suitable for local families, sparking debate over who this new housing is for even as the neighborhood needs more homes; the plan also includes unused development rights and has sparked broader community discussion about balancing growth with residents' needs.

via COLlive|
#crown-heights#development#grun-group-llc