Tag

Egfr

All articles tagged with #egfr

science1 month ago•3 min saved

Membrane lipids can lock EGFR in constant growth mode, MIT study shows

MIT researchers show that the lipid makeup of the cell membrane can directly control the EGFR receptor: high levels of negatively charged lipids push EGFR into a permanently active state, driving continuous pro-growth signaling and cancer-like proliferation; cholesterol can dampen this signaling by making membranes stiffer. The study uses nanodiscs and single-molecule FRET to examine full-length EGFR behavior, suggesting new cancer therapies could target membrane lipids to neutralize EGFR activity.

via MIT News|

#cancer #cell-membrane #egfr

health5 months ago•2 min saved

Top Doctor Shares 4 Easy Tests for Early Kidney Disease Detection

Kidney diseases are increasing rapidly, and early detection through simple tests like eGFR, Cystatin C, urine dipstick, and protein-to-creatinine ratio is crucial for effective treatment. Regular screening can help identify silent issues before they worsen, and consulting a nephrologist is recommended if abnormalities are found.

via The Times of India|

#cystatin-c #early-detection #egfr

health9 months ago•4 min saved

Cannabis and Cancer: Risks and Effects on Healing and Treatment

Some studies suggest heavy cannabis use may increase the risk of certain cancers due to its effects on lung immunity and cellular growth pathways like EGFR, but more research is needed to confirm these links, and current evidence is mixed. Cannabis smoke contains carcinogens similar to tobacco, and its impact on immune defenses and cellular mechanisms could potentially promote cancer development, though it may also offer benefits for cancer patients.

via Live Science|

#cancer #cannabis #egfr

health2 years ago•10 min saved

"Essential Guide: Recognizing Kidney Disease Stages and Warning Signs for Optimal Kidney Health"

Chronic kidney disease (CKD) is divided into five stages based on the estimated glomerular filtration rate (eGFR), which measures kidney function. Each stage represents a different level of kidney damage and requires specific treatments. In the early stages (1-3), there may be no symptoms, but as the disease progresses, symptoms such as foamy urine, fatigue, and swelling may occur. In the later stages (4-5), kidney function significantly declines, leading to complications and the need for dialysis or a kidney transplant. Regular monitoring and early intervention can slow down the progression of CKD and improve outcomes.

via Verywell Health|

#chronic-kidney-disease #egfr #health

health3 years ago•3 min saved

"Assessing Kidney Health: The Importance of Two Simple Tests and Public-Private Partnerships"

Two important medical tests, estimated Glomerular Filtration Rate (eGFR) and urine Albumin-Creatinine Ratio (uACR), can help detect chronic kidney disease (CKD) early. eGFR measures how well kidneys clean blood, while uACR measures the presence of albumin in urine, indicating kidney damage. CKD is often underdiagnosed in India, where it is a rising burden on healthcare. Regular monitoring and early treatment can improve the outlook for CKD patients.

via Times of India|

#chronic-kidney-disease #egfr #health

health3 years ago•3 min saved

Environmental Risks: 3 Years of Air Pollution Linked to Lung Cancer

Exposure to high concentrations of tiny particles in the air can increase the risk of developing lung cancer within just three years, according to a comprehensive study of nearly 33,000 people with lung cancer. The research also provides new insights on the disease's progression, with the polluting haze being especially dangerous to healthy lung tissue featuring genetic changes that put it at risk of turning cancerous. The study found that air pollution wakes up cells in the lungs, encouraging them to grow and potentially form tumors. The researchers emphasize the need for action to reduce pollution and protect public health.

via ScienceAlert|

#air-pollution #cancer-research #egfr