All articles tagged with #immune signaling
McMaster University researchers have shown that statins can disrupt muscle cell energy production, triggering immune signaling that leads to inflammation and muscle damage. Blocking this immune response reduced damage, suggesting side effects may be separable from cholesterol-lowering benefits and could guide future therapies to improve statin tolerability.
Preclinical study in a mouse model of Alzheimer's found inhaled cannabidiol (CBD) reduced key inflammatory pathways (IDO and cGAS), lowered proinflammatory cytokines, and improved recognition memory, suggesting CBD may exert a multitarget anti-inflammatory effect that could complement other approaches. However, results are early and in animals, and human studies are needed to assess safety and efficacy.
Scientists at Cedars-Sinai discovered a new role for astrocytes, called lesion-remote astrocytes (LRAs), which communicate with immune cells to clear debris and promote repair in spinal cord injuries, potentially leading to new treatments for neurological diseases.