Tag

Mitochondrialdysfunction

All articles tagged with #mitochondrialdysfunction

science1 month ago•7 min saved

Kaempferol slows spaceflight knee cartilage damage in mice

A University of Pittsburgh–led study reported that mice exposed to spaceflight-like conditions (ISS and ground-based microgravity with radiation) developed knee cartilage damage, but oral kaempferol reduced cartilage loss, preserved mitochondria, and lowered inflammation by inhibiting NOX4-driven oxidative stress. While promising for long-duration spaceflight and insights into knee osteoarthritis, the findings are preliminary—no human testing and dietary kaempferol effects remain unproven.

via ScienceAlert|

#kaempferol #kneecartilage #mitochondrialdysfunction

health1 year ago•2 min saved

Cannabis Use Tied to Genetic Damage and Increased Cancer Risk

A study published in Addiction Biology links cannabis use to significant genetic and cellular damage, increasing cancer risks and potentially affecting future generations. The research identifies cannabis as a genotoxic substance, capable of causing DNA mutations and mitochondrial dysfunction, which can lead to cancer, premature aging, and birth defects. These findings suggest that the genetic damage from cannabis could be passed down through generations, raising concerns about its long-term impact and implications for cannabis legalization discussions.

via SciTechDaily|

#cancerrisk #cannabis #geneticdamage

health-and-medicine2 years ago•3 min saved

"Study Links Mitochondrial Dysfunction to Debilitating Exercise Fatigue in Long COVID Patients"

Researchers at Amsterdam University Medical Center have discovered that the fatigue experienced by long Covid patients is due to reduced energy production by mitochondria in muscle cells. The study involved a cycling test that led to post-exertional malaise in long Covid patients, highlighting a biological cause for their fatigue. The findings suggest that intense exercise may not be beneficial for these patients and that treatments should focus on managing energy levels within individual limits. The study, which offers new insights into the treatment and management of long Covid symptoms, is published in the journal Nature Communications.

via Earth.com|

##covid19research #fatigue

health2 years ago•2 min saved

"Study Links Cellular Changes to Exercise Intolerance in Long Covid Patients"

A study from Vrije Universiteit Amsterdam, published in Nature Communications, has found that people with long Covid experience severe muscle damage, mitochondrial problems, and the presence of microclots, leading to debilitating symptoms after exercise. The research involved 25 long Covid patients and 21 recovered individuals, revealing that those with long Covid had a lower exercise capacity, more white muscle fibers with fewer mitochondria and capillaries, and significant tissue damage post-exercise. The findings suggest that intense exercise can exacerbate symptoms and that treatments improving mitochondrial health could be beneficial.

via The Guardian|

##exercisedebilitation #health