Tag

Pam

All articles tagged with #pam

Louisiana 8-year-old loses life to rare brain-eating amoeba after freshwater exposure
health1 day ago

Louisiana 8-year-old loses life to rare brain-eating amoeba after freshwater exposure

An 8-year-old girl in Louisiana has died after contracting a brain-eating amoeba, Naegleria fowleri, from freshwater. Infections with this microbe cause primary amoebic meningoencephalitis (PAM) and are extremely rare but typically fatal. Transmission occurs when contaminated water enters the nose during swimming or wading in warm, untreated freshwater; it is not spread person-to-person. Health officials urge precautions around warm lakes and rivers, including avoiding nasal exposure and using nose clips or other barriers when possible.

Louisiana Resident Hospitalized After Lake Swim for Rare Brain-Eating Amoeba
health4 days ago

Louisiana Resident Hospitalized After Lake Swim for Rare Brain-Eating Amoeba

A Louisiana resident is hospitalized after contracting primary amebic meningoencephalitis (PAM), a rare brain infection caused by the brain-eating amoeba Naegleria fowleri, from swimming in Lake Claiborne. PAM has a about a 97% fatality rate with only four U.S. survivors since 1937. Health officials warn that warm freshwater lakes and inadequately chlorinated pools can harbor the amoeba, and prevention focuses on nose protection when in such waters; there is currently no reliable method to reduce amoebas in water.

Two-stage PamStealer malware stealthily harvests macOS passwords via PAM validation
technology1 month ago

Two-stage PamStealer malware stealthily harvests macOS passwords via PAM validation

Researchers uncovered PamStealer, a two-stage macOS infostealer that uses a disk-image lure masquerading as Maccy, a self-contained JavaScript for Automation downloader, and a Rust-based second stage. It validates passwords locally through macOS PAM before exfiltrating credentials, while staying stealthy by disguising as Finder, encrypting C2 traffic, and delaying prompts to avoid detection.

A Decade-Long Auth Breach: Velvet Ant Taps Air-Gapped Network for Espionage
technology2 months ago

A Decade-Long Auth Breach: Velvet Ant Taps Air-Gapped Network for Espionage

Velvet Ant's Operation Highland spent a decade in an organization’s air-gapped network after pivoting from internet-facing hosts, hijacking authentication by replacing PAM modules and OpenSSH components with backdoors, and building a remote-execution path via modified Nginx/FCGI to issue commands over HTTP; initial access used a GS-Netcat reverse shell and a SOCKS5 proxy to reach internal systems; this gave attackers full visibility into admin activity and allowed credential theft, with persistence surviving password resets; remediation is complex and requires hardening PAM/OpenSSH, MFA, EDR, FIM, offline immutable backups, rigorous testing, and rollback planning.

New Treatments Bring Hope Against Deadly Brain-Eating Amoebas
health4 months ago

New Treatments Bring Hope Against Deadly Brain-Eating Amoebas

Infections by Naegleria fowleri, which cause primary amebic meningoencephalitis (PAM), are almost always fatal (over 97%); however, miltefosine—an anti-leishmaniasis drug that can cross the blood–brain barrier—has saved several patients since 2013, spurring research into alternatives like nitroxoline and potential vaccines, as well as other strategies. The key to improving outcomes remains rapid diagnosis and access to treatment, though funding challenges for trials in this rare disease persist. Climate warming of waterways could raise exposure in the future, prompting renewed urgency in PAM research.

Genetic GLP-1 Resistance Could Explain Uneven Ozempic Responses
health-and-medicine4 months ago

Genetic GLP-1 Resistance Could Explain Uneven Ozempic Responses

Stanford-led research links PAM gene variants to GLP-1 resistance, where higher GLP-1 levels do not translate to better blood-sugar control, helping explain why roughly 10% of people respond poorly to Ozempic- and Wegovy-like drugs; the findings point toward precision medicine and may favor longer-acting GLP-1 therapies or alternatives for those with the variants.

Child Dies from Brain-Eating Amoeba at Lake Murray in South Carolina
health1 year ago

Child Dies from Brain-Eating Amoeba at Lake Murray in South Carolina

A patient in a South Carolina children's hospital has died from primary amebic meningoencephalitis caused by the brain-eating amoeba Naegleria fowleri, likely contracted from Lake Murray, marking the first case in the state since 2016. The infection is highly fatal, occurring when contaminated water enters the brain through the nose during recreational water activities. Health officials advise precautions like nose clips to reduce risk.

Texas Woman Dies After Sinus Rinse with Tap Water: Brain-Eating Amoeba Risks
health1 year ago

Texas Woman Dies After Sinus Rinse with Tap Water: Brain-Eating Amoeba Risks

A 71-year-old woman in Texas died after contracting the deadly brain-eating amoeba Naegleria fowleri through nasal rinsing with tap water. The amoeba, which thrives in warm freshwater and soil, causes a rare but almost always fatal brain infection called Primary Amoebic Meningoencephalitis (PAM). Although infections are extremely rare, rising global temperatures and increased water activities during hot weather are contributing to more cases worldwide. Prevention includes proper water disinfection, avoiding warm freshwater during high temperatures, and using nose plugs or distilled water for nasal rinsing.

Texas Woman Dies from Brain-Eating Amoeba After Using Tap Water for Sinus Rinse
health1 year ago

Texas Woman Dies from Brain-Eating Amoeba After Using Tap Water for Sinus Rinse

A Texas woman died after using contaminated tap water for sinus rinsing, highlighting the dangers of Naegleria fowleri, a rare but deadly brain-eating amoeba. The infection, primary amebic meningoencephalitis (PAM), is almost always fatal and occurs when contaminated water enters the nose, typically in warm freshwater environments. Prevention includes avoiding untreated water for nasal irrigation and swimming in chlorinated pools or oceans. Early detection and treatment are critical, but the disease remains highly lethal with very few survivors.

health3 years ago

Climate Change Spurs Spread of Deadly Brain-Eating Amoebas in Northern US States

Rising temperatures attributed to climate change are causing the "brain-eating" amoeba, Naegleria fowleri, to move northward, posing a greater threat to human health in new regions where primary amebic meningoencephalitis (PAM) has not yet been documented. Although rare, the amoeba can cause a fatal infection if it enters the body through the nose and travels to the brain. Public health agencies are warning medical professionals of the potential threat and a case report has been published to help health care providers detect and treat N. fowleri infection.