All articles tagged with #phase 2
In a mid-stage Phase 2 trial, Biogen's experimental Alzheimer’s drug diranersen slowed cognitive decline to rates similar to approved therapies and reduced brain tau, a result that supports advancing to Phase 3 pending confirmation.
Maryland canceled its Phase 2 contract with Kiewit for the Francis Scott Key Bridge after bids exceeded state estimates, forcing a rebid as costs balloon from about $1.8B to over $5B; Gov. Wes Moore defends a fast, safe rebuild while USDOT emphasizes taxpayer protections and oversight, with MDTA planning an industry forum to select a new contractor and Phase 1 work continuing.
Detroit’s Phase 2 plan centers on adding affordable, versatile veterans to complement a rising roster. The piece lists nine overlooked targets across edge, interior line, cornerback, safety, and offensive line, weighing pros and cons (age, health, fit) and advocating a value-first approach aligned with Brad Holmes’ draft-first philosophy, using data from the Fantasy Points Data Suite to evaluate each option.
Ocugen reports preliminary phase 2 data for OCU410 to treat geographic atrophy (GA) from dry AMD, with the medium dose showing a 54% reduction in lesion growth vs placebo at 12 months and the high dose 36% in a small patient subset, raising questions about dose response; Ocugen aims to present full data this quarter and move to phase 3 by year-end, targeting an FDA filing in 2028, and argues the therapy could outperform Apellis' Syfovre and Astellas' Izervay.
World of Warcraft Classic's Season of Discovery Phase 2 introduces Gnomeregan raid dungeon, new loot, profession updates, and PvP event "The Blood Moon" in Stranglethorn Vale. The update also includes boss and dungeon updates, new rune abilities for various classes, PvP matchmaking adjustments, and a ban on GDKP runs. The phase goes live on February 8 at 1:00 pm PST.
Ronald Acuña Jr. has been selected as one of the National League's starting outfielders for the 2023 All-Star Game, having received the most votes during Phase 1 of the balloting process. He will be joined by six other Atlanta Braves players who advanced to Phase 2 of the voting. Fans can vote once per day during this second phase, with daily voting limits resetting each day at midnight ET. Winners will be announced on June 29th.
The finalists for the 2023 MLB All-Star Game have been announced, with Ronald Acuña Jr. of the Braves and Shohei Ohtani of the Angels earning automatic starting spots. The top two vote-getters at each position and the top six outfielders are advancing to Phase 2 of the voting, which begins on Monday. Fans can vote once per 24-hour period on MLB platforms until Thursday. The All-Star starters will be revealed on June 29.