Tag

Quetiapine

All articles tagged with #quetiapine

health2 months ago•7 min saved

Quetiapine Eases Sleep Apnea Yet Impairs Morning Driving

A small randomized trial in 15 adults with obstructive sleep apnea and sleep-maintenance difficulties found that taking 50 mg of quetiapine before bed increased total sleep time and reduced apnea events, but tripled morning attention lapses and worsened driving performance in a simulator. Researchers caution against driving for about 9.5 hours after dosing and note the study’s small size and single-night design, with sex-based differences in drug metabolism potentially influencing effects. Larger studies are needed to confirm the trade-offs between sleep benefits and daytime functioning.

via Fox News|

#cognitive-impairment #driving-impairment #health

health2 months ago•5 min saved

Low-dose quetiapine may worsen next-day alertness in sleep apnea patients

A small trial (15 participants) in obstructive sleep apnea found that low-dose quetiapine can extend sleep but impairs next-day cognitive function and driving performance, with slower reaction times and more attention lapses; some did not feel sleepy despite worse performance. The study cautions against using quetiapine as routine sleep medication for sleep apnea and calls for larger, longer studies and more personalized treatment approaches.

via ScienceAlert|

#alertness #health #insomnia

california5 months ago•5 min saved

Kratom-Linked Meds Cited in Beutner Daughter’s Death; Suicide Ruled

The Los Angeles County Medical Examiner ruled that 22-year-old Emily Beutner’s death was a suicide, caused by the combined effects of kratom compounds (mitragynine and 7-hydroxymitragynine) with prescription antipsychotic quetiapine and antidepressant mirtazapine; she was found by a Palmdale roadside after midnight on Jan. 6 and died after being hospitalized at 2:10 a.m. Her death occurred while her father, former LAUSD superintendent Austin Beutner, was grieving and had recently ended his bid for mayor.

via Los Angeles Times|

#california #emily-beutner #kratom

health2 years ago•3 min saved

Head-to-Head Trial Declares Esketamine Superior to Quetiapine for Treatment-Resistant Depression

A head-to-head trial sponsored by Janssen, the maker of esketamine spray, compared the effectiveness of nasal esketamine spray to quetiapine, an extended-release antipsychotic, in patients with treatment-resistant depression. The study found that esketamine was more effective than quetiapine when taken in combination with SSRIs and SNRIs. At eight weeks, 27% of patients treated with esketamine were in remission compared to 17% of those taking quetiapine. Esketamine patients in remission at week eight were more likely to remain in remission until week 32. Patients taking esketamine were also more likely to adhere to the treatment. The study suggests that a longer initial course of esketamine treatment may be more effective and calls for further research to identify patients who are likely to respond positively to the drug.

via STAT|

#antidepressants #clinical-trial #esketamine