Tag

Antidepressants

All articles tagged with #antidepressants

New Study Links Antidepressant Tapering Distress to Withdrawal, Not Relapse
health13 days ago

New Study Links Antidepressant Tapering Distress to Withdrawal, Not Relapse

A new study suggests that emotional distress during antidepressant tapering is likely a withdrawal reaction rather than a relapse. Researchers found that anxiety and depression spikes correlate with physical withdrawal symptoms, indicating a pharmacological response. This distinction is crucial for patient care, as it suggests slower tapering may be more effective than resuming medication. The findings challenge current diagnostic practices that often misinterpret withdrawal as a return of the underlying mental health condition.

The Complex Case Behind America’s Rising Antidepressant Use
health29 days ago

The Complex Case Behind America’s Rising Antidepressant Use

Since the pandemic, anxiety and depression have risen and antidepressant prescriptions have surged, with about one in six American adults taking them and SSRIs making up the majority. The piece argues the trend is nuanced: some overuse is possible, but expanded access to mental health care—especially through primary care and telehealth—has also helped people in need. Prescribing is mainly done in primary care, and stopping antidepressants can be difficult for some, though gradual tapering under medical supervision is often possible. Systemic barriers mean many with serious depression still receive limited treatment, underscoring the need to balance medication with nonpharmacological options and broader access to care.

Depression Tied to Shrinkage in a Key Memory Hub in the Brain
science1 month ago

Depression Tied to Shrinkage in a Key Memory Hub in the Brain

A USC-led study using MRI and PET scans of over 2,000 cognitively normal adults found that depression is linked to a smaller CA23DG portion of the hippocampus (comprising CA2/CA3 and the dentate gyrus), an association that largely held even after accounting for Alzheimer's risk factors. Antidepressant use and longer duration of depression were also associated with greater volume reductions in related hippocampal subregions, though the findings are correlational and do not establish causation or warrant changing treatment. Further longitudinal research is needed to understand the mechanisms at play.

US presses deprescribing drive to curb antidepressant use
health-policy2 months ago

US presses deprescribing drive to curb antidepressant use

Health Secretary RFK Jr. is advancing a deprescribing initiative to reduce antidepressant use. Federal officials and mental health professionals gathered to draft forthcoming clinical guidance on tapering SSRIs and expanding nonmedication options like therapy, while highlighting gaps in research on withdrawal symptoms and relapse versus recurrence of depressive symptoms.

Common meds can impair heat tolerance, experts warn
health3 months ago

Common meds can impair heat tolerance, experts warn

Experts warn that certain allergy medications can disrupt the body's ability to regulate temperature and sweat, and mood-regulating drugs like antidepressants and antipsychotics may affect how the body senses heat, increasing risk during hot weather. Pharmacists advise reviewing high-risk meds with a doctor or pharmacist and watching for warning signs such as excessive sweating or no sweating at all.

RFK Jr.’s antidepressant curbs could reshape US mental health care
world4 months ago

RFK Jr.’s antidepressant curbs could reshape US mental health care

RFK Jr.’s latest HHS policy calls for reducing antidepressant use in depression and expanding non-drug options like therapy, diet, exercise, and social support to tackle so‑called overmedicalisation of mental health. While some experts welcome a more cautious approach, many caution that antidepressants (especially SSRIs) help many patients and that deprescribing must be careful and context‑aware, given access barriers and complex needs. With roughly a third of Americans having used antidepressants, the policy could change treatment dynamics, but real‑world impact will depend on resources, implementation, and ensuring patients aren’t left untreated.

Parental mental health—not meds—drive autism links in pregnancy, study finds
science-and-medicine4 months ago

Parental mental health—not meds—drive autism links in pregnancy, study finds

A Lancet review of 37 studies with over 25 million pregnancies finds that the association between prenatal antidepressant use and autism/ADHD largely disappears after accounting for maternal depression and family history. The data show children of mothers with depression are more likely to be diagnosed with autism/ADHD, and paternal antidepressant use during gestation also correlates with these conditions, suggesting a genetic rather than pharmacological link. The authors note that current guidelines supporting continuation of antidepressants during pregnancy, when clinically indicated, are reinforced, and emphasize weighing the risks of untreated maternal depression against medication exposure.

Pregnancy antidepressants not tied to autism or ADHD risk, meta-analysis suggests
health4 months ago

Pregnancy antidepressants not tied to autism or ADHD risk, meta-analysis suggests

A large meta-analysis of over half a million pregnancies found no significant link between maternal antidepressant use during pregnancy and autism or ADHD in children after adjusting for maternal mental health and other factors; any initial signals disappeared when confounders were controlled. The findings support continuing antidepressant treatment for moderate-to-severe depression during pregnancy, though decisions should be individualized with a clinician and study limitations include missing socioeconomic and lifestyle data.

Pregnant antidepressant use largely not linked to ADHD or autism after accounting for confounders
health4 months ago

Pregnant antidepressant use largely not linked to ADHD or autism after accounting for confounders

A Lancet Psychiatry meta-analysis of 37 studies with over 600,000 pregnancies found that prenatal antidepressant exposure has little to no association with ADHD or autism after adjusting for genetics and family factors; older antidepressants may show small links, but overall the findings reassure the safety of contemporary antidepressants during pregnancy, while highlighting the risks of untreated maternal depression.

Gottlieb: hantavirus risk low, FDA turmoil looms, antidepressant debate
health5 months ago

Gottlieb: hantavirus risk low, FDA turmoil looms, antidepressant debate

In a May 10 interview on Face the Nation, former FDA commissioner Scott Gottlieb says the hantavirus outbreak linked to a cruise ship presents low transmission risk but could yield additional cases as repatriations continue and the incubation window plays out; he criticizes ongoing leadership turnover and staff losses at the FDA, defends the continued use of antidepressants when properly prescribed and warns against abrupt stopping, and rejects ivermectin as an effective treatment while urging reliance on medical guidance.

RFK Jr. targets antidepressants with debunked heroin comparison, prompting deprescribing push
health5 months ago

RFK Jr. targets antidepressants with debunked heroin comparison, prompting deprescribing push

At a MAHA event, RFK Jr. announced steps to curb SSRI prescribing, repeating debunked claims that antidepressants are as addictive as heroin. Experts say the comparison is unfounded and emphasize careful, evidence-based deprescribing. The plan includes clinician training, a Dear Colleague letter, and CMS guidance with a new billing code to help taper patients off meds, but medical groups warn against framing mental-health care as overmedicalization and cite access issues.

RFK Jr backs plan to curb antidepressants and expand nondrug care
health5 months ago

RFK Jr backs plan to curb antidepressants and expand nondrug care

Robert F. Kennedy Jr. unveiled a federal plan to curb antidepressant prescribing, with the Department of Health and Human Services promoting deprescribing and the use of nonpharmacological treatments (psychotherapy, diet, exercise, social connection) when appropriate. The plan includes provider guidance and reimbursements for deprescribing, while the APA welcomed the focus but warned that deprescribing alone won't fix access and workforce gaps in mental health care. A 2025 survey found ~17% of Americans use antidepressants, and Kennedy has claimed—without evidence—that SSRIs contribute to school shootings.

Massive IBS Drug Study Finds Small Mortality Rise With Some Treatments
health5 months ago

Massive IBS Drug Study Finds Small Mortality Rise With Some Treatments

A large, nearly 20-year study of 650,000+ US adults with IBS linked long-term antidepressant use to about a 35% higher risk of death and showed the anti-diarrheal drugs loperamide and diphenoxylate associated with roughly double the risk, though the study notes it shows association, not causation, and the overall individual risk remains low; findings prompt personalized treatment and more long-term safety research.