Tag

Antidepressants

All articles tagged with #antidepressants

Depression Tied to Shrinkage in a Key Memory Hub in the Brain
science9 days ago

Depression Tied to Shrinkage in a Key Memory Hub in the Brain

A USC-led study using MRI and PET scans of over 2,000 cognitively normal adults found that depression is linked to a smaller CA23DG portion of the hippocampus (comprising CA2/CA3 and the dentate gyrus), an association that largely held even after accounting for Alzheimer's risk factors. Antidepressant use and longer duration of depression were also associated with greater volume reductions in related hippocampal subregions, though the findings are correlational and do not establish causation or warrant changing treatment. Further longitudinal research is needed to understand the mechanisms at play.

US presses deprescribing drive to curb antidepressant use
health-policy1 month ago

US presses deprescribing drive to curb antidepressant use

Health Secretary RFK Jr. is advancing a deprescribing initiative to reduce antidepressant use. Federal officials and mental health professionals gathered to draft forthcoming clinical guidance on tapering SSRIs and expanding nonmedication options like therapy, while highlighting gaps in research on withdrawal symptoms and relapse versus recurrence of depressive symptoms.

Common meds can impair heat tolerance, experts warn
health1 month ago

Common meds can impair heat tolerance, experts warn

Experts warn that certain allergy medications can disrupt the body's ability to regulate temperature and sweat, and mood-regulating drugs like antidepressants and antipsychotics may affect how the body senses heat, increasing risk during hot weather. Pharmacists advise reviewing high-risk meds with a doctor or pharmacist and watching for warning signs such as excessive sweating or no sweating at all.

RFK Jr.’s antidepressant curbs could reshape US mental health care
world2 months ago

RFK Jr.’s antidepressant curbs could reshape US mental health care

RFK Jr.’s latest HHS policy calls for reducing antidepressant use in depression and expanding non-drug options like therapy, diet, exercise, and social support to tackle so‑called overmedicalisation of mental health. While some experts welcome a more cautious approach, many caution that antidepressants (especially SSRIs) help many patients and that deprescribing must be careful and context‑aware, given access barriers and complex needs. With roughly a third of Americans having used antidepressants, the policy could change treatment dynamics, but real‑world impact will depend on resources, implementation, and ensuring patients aren’t left untreated.

Parental mental health—not meds—drive autism links in pregnancy, study finds
science-and-medicine3 months ago

Parental mental health—not meds—drive autism links in pregnancy, study finds

A Lancet review of 37 studies with over 25 million pregnancies finds that the association between prenatal antidepressant use and autism/ADHD largely disappears after accounting for maternal depression and family history. The data show children of mothers with depression are more likely to be diagnosed with autism/ADHD, and paternal antidepressant use during gestation also correlates with these conditions, suggesting a genetic rather than pharmacological link. The authors note that current guidelines supporting continuation of antidepressants during pregnancy, when clinically indicated, are reinforced, and emphasize weighing the risks of untreated maternal depression against medication exposure.

Pregnancy antidepressants not tied to autism or ADHD risk, meta-analysis suggests
health3 months ago

Pregnancy antidepressants not tied to autism or ADHD risk, meta-analysis suggests

A large meta-analysis of over half a million pregnancies found no significant link between maternal antidepressant use during pregnancy and autism or ADHD in children after adjusting for maternal mental health and other factors; any initial signals disappeared when confounders were controlled. The findings support continuing antidepressant treatment for moderate-to-severe depression during pregnancy, though decisions should be individualized with a clinician and study limitations include missing socioeconomic and lifestyle data.

Pregnant antidepressant use largely not linked to ADHD or autism after accounting for confounders
health3 months ago

Pregnant antidepressant use largely not linked to ADHD or autism after accounting for confounders

A Lancet Psychiatry meta-analysis of 37 studies with over 600,000 pregnancies found that prenatal antidepressant exposure has little to no association with ADHD or autism after adjusting for genetics and family factors; older antidepressants may show small links, but overall the findings reassure the safety of contemporary antidepressants during pregnancy, while highlighting the risks of untreated maternal depression.

Gottlieb: hantavirus risk low, FDA turmoil looms, antidepressant debate
health3 months ago

Gottlieb: hantavirus risk low, FDA turmoil looms, antidepressant debate

In a May 10 interview on Face the Nation, former FDA commissioner Scott Gottlieb says the hantavirus outbreak linked to a cruise ship presents low transmission risk but could yield additional cases as repatriations continue and the incubation window plays out; he criticizes ongoing leadership turnover and staff losses at the FDA, defends the continued use of antidepressants when properly prescribed and warns against abrupt stopping, and rejects ivermectin as an effective treatment while urging reliance on medical guidance.

RFK Jr. targets antidepressants with debunked heroin comparison, prompting deprescribing push
health3 months ago

RFK Jr. targets antidepressants with debunked heroin comparison, prompting deprescribing push

At a MAHA event, RFK Jr. announced steps to curb SSRI prescribing, repeating debunked claims that antidepressants are as addictive as heroin. Experts say the comparison is unfounded and emphasize careful, evidence-based deprescribing. The plan includes clinician training, a Dear Colleague letter, and CMS guidance with a new billing code to help taper patients off meds, but medical groups warn against framing mental-health care as overmedicalization and cite access issues.

RFK Jr backs plan to curb antidepressants and expand nondrug care
health3 months ago

RFK Jr backs plan to curb antidepressants and expand nondrug care

Robert F. Kennedy Jr. unveiled a federal plan to curb antidepressant prescribing, with the Department of Health and Human Services promoting deprescribing and the use of nonpharmacological treatments (psychotherapy, diet, exercise, social connection) when appropriate. The plan includes provider guidance and reimbursements for deprescribing, while the APA welcomed the focus but warned that deprescribing alone won't fix access and workforce gaps in mental health care. A 2025 survey found ~17% of Americans use antidepressants, and Kennedy has claimed—without evidence—that SSRIs contribute to school shootings.

Massive IBS Drug Study Finds Small Mortality Rise With Some Treatments
health4 months ago

Massive IBS Drug Study Finds Small Mortality Rise With Some Treatments

A large, nearly 20-year study of 650,000+ US adults with IBS linked long-term antidepressant use to about a 35% higher risk of death and showed the anti-diarrheal drugs loperamide and diphenoxylate associated with roughly double the risk, though the study notes it shows association, not causation, and the overall individual risk remains low; findings prompt personalized treatment and more long-term safety research.

Long-Term Antidepressant Use Linked to Elevated Risk of Sudden Cardiac Death, Danish Study Finds
health4 months ago

Long-Term Antidepressant Use Linked to Elevated Risk of Sudden Cardiac Death, Danish Study Finds

A Danish nationwide cohort study of more than 4 million adults found that longer antidepressant use is associated with an increased risk of sudden cardiac death, with adjusted hazards of 1.41 for 1–5 years and 1.74 for six or more years; current users face the highest risk, though the study cannot prove causality due to its observational design and potential residual confounding. The findings suggest a time-dependent risk across antidepressant subclasses, and further research is needed to clarify causality and mechanisms.

UK teens increasingly prescribed antidepressants as specialist access lags
health5 months ago

UK teens increasingly prescribed antidepressants as specialist access lags

BBC analysis shows about 70,000 under-18s in England are prescribed antidepressants each year, with guidelines urging psychiatrist assessment first. But long waits for specialist help have some GPs prescribing or starting treatment outside guidelines to avoid leaving patients untreated, while others refuse. Antidepressants are used for depression, anxiety, bedwetting and pain and can have side effects; the NHS notes workforce growth but record demand remains, prompting calls for more accompanying mental health support and timely CAMHS access.