Genetic Analysis of 194-Year-Old Tortoise Jonathan Reveals Stable Mitochondrial Gene Regulation
Researchers have analyzed the DNA and epigenome of Jonathan, the 194-year-old Aldabra giant tortoise, finding 287 unique gene variants that suppress aging. A key discovery is that chemical tags regulating his mitochondria remain as orderly as those in young tortoises, suggesting a feedback loop that maintains cellular energy production and DNA repair. Published in Science Advances, the study offers insights into extreme longevity, though experts note the findings require further validation to confirm causality.
