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Sperm Production

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Testosterone therapy may sacrifice fertility and trigger unexpected side effects, doctors warn
health1 month ago

Testosterone therapy may sacrifice fertility and trigger unexpected side effects, doctors warn

A New York Post report cites doctors warning that testosterone replacement therapy (TRT) is widely used—often via online scripts—yet it can dramatically reduce sperm production, risking infertility for men who want future children; side effects can include acne, breast development, and testicular shrinkage, and high testosterone may raise blood pressure and heart risk without proper medical supervision. Because many men skip in-person evaluation, experts urge regular monitoring and consider alternatives like clomiphene, enclomiphene, or hCG to raise testosterone while preserving fertility, while also addressing sleep apnea, obesity, or other root causes.

via New York Post|
#fertility#health#mens-health
Male Fertility Demystified: Key Factors and When to Seek Testing
health1 month ago

Male Fertility Demystified: Key Factors and When to Seek Testing

About half of infertility cases involve male factors. Dr. Sanjay Prakash J explains how lifestyle (stress, poor sleep, obesity, smoking, excessive alcohol, drugs, steroids), medical conditions (varicocele, diabetes, thyroid disorders, infections, chemotherapy/radiation), and genetics can impair sperm production. For couples not conceiving after a year of unprotected intercourse (or men over 35), evaluation is advised, with early diagnosis aiding family planning and genetic counselling. Premarital fertility checks are also encouraged as part of proactive health planning.

via Hindustan Times|
#fertility-assessment#health#infertility
Pause-and-resume sperm strategy edges closer to reversible male birth control
science4 months ago

Pause-and-resume sperm strategy edges closer to reversible male birth control

A Cornell University study in mice shows that sperm production can be paused by targeting a meiosis checkpoint using the molecule JQ1, stopping sperm development and then resuming after stopping the drug; fertility returns and offspring are healthy, suggesting a nonhormonal, reversible path toward long-acting male contraception in the future, though it is not consumer-ready and currently involves a drug with neurological side effects.

via Earth.com|
#cornell-study#male-birth-control#meiosis-checkpoint
"Excessive Video Game Playing Linked to Tripled Risk of Erectile Dysfunction and Low Sperm Count"
health2 years ago

"Excessive Video Game Playing Linked to Tripled Risk of Erectile Dysfunction and Low Sperm Count"

A study in China found that spending 1.2 hours per day playing video games or engaging in leisure activities on the computer triples the risk of erectile dysfunction (ED) in men. This was linked to lower levels of follicle-stimulating hormone (FSH), which stimulates sperm production. The study did not find a similar risk associated with watching TV or driving for leisure. The rise in ED cases has been attributed to factors such as obesity, poor mental health, and excessive pornography consumption. However, the study has limitations, and further research is needed to establish a definitive causal association between computer use and ED.

via Daily Mail|
#computer-use#erectile-dysfunction#health
"Non-Hormonal Male Birth Control: A Promising, Side-Effect-Free Breakthrough"
health-and-medicine2 years ago

"Non-Hormonal Male Birth Control: A Promising, Side-Effect-Free Breakthrough"

The Salk Institute has developed a non-hormonal and reversible male contraceptive method using HDAC inhibitors to block sperm production without affecting libido, offering a significant advancement in male birth control. Administering an HDAC inhibitor orally stopped sperm production and fertility in mice without impacting their libido, and the effects were fully reversible. This novel approach targets the regulation of gene expression in sperm production, providing a promising therapeutic approach for human clinical trials.

via SciTechDaily|
#hdac-inhibitors#health-and-medicine#male-birth-control
"Breakthrough Male Birth Control Pill and Implant: A Game Changer for Contraception"
health-and-science2 years ago

"Breakthrough Male Birth Control Pill and Implant: A Game Changer for Contraception"

Scientists at the Salk Institute have developed a non-hormonal and reversible male contraceptive pill that targets a specific protein complex involved in sperm production, showing promising results in male mice without apparent side-effects. The method disrupts the genetic program responsible for sperm production using existing drugs called HDAC inhibitors, and once the treatment is stopped, fertility returns to normal. Further research and clinical trials are needed, but this breakthrough offers a potential new option for male birth control with minimal systemic side-effects.

via Study Finds|
#birth-control#clinical-trials#genetic-breakthrough
Unveiling the Mystery: The Root Cause of Male Infertility Revealed
health2 years ago

Unveiling the Mystery: The Root Cause of Male Infertility Revealed

Scientists from the Stowers Institute for Medical Research and the Wellcome Center for Cell Biology have identified a potential underlying cause of male infertility. The researchers discovered that a specific mutation in a protein involved in the formation of the synaptonemal complex, a critical structure in the process of sperm and egg cell production, led to infertility in mice. This finding may shed light on similar problems with meiosis in humans and could pave the way for potential treatments.

via Medical Xpress|
#health#male-infertility#meiosis
The Dangers of Sitting with Crossed Legs.
health3 years ago

The Dangers of Sitting with Crossed Legs.

Sitting with legs crossed for prolonged periods can increase the misalignment of the hips, change the speed of blood flow, and increase the risk of blood clots. It can also cause misalignment of the spine and shoulders, weaken muscles, and affect sperm production. However, sitting cross-legged can be beneficial for some people, such as those with one leg longer than the other. The verdict is to avoid crossing legs if possible, but the main advice is to not sit still in the same position for too long and to keep regularly active.

via IFLScience|
#blood-clots#health#posture