All articles tagged with #tadalafil
Italian researchers found that tadalafil, the active ingredient in Cialis, increased the growth and survival of muscle precursor cells in a seven-day lab study. While the drug showed potential for aiding muscle repair, it also delayed the maturation of these cells into functional muscle fibers. Experts caution that these results are preliminary and do not prove the drug builds muscle in humans.
A large observational study finds that men taking daily tadalafil (Cialis) for enlarged prostates have a 22% higher relative risk of glaucoma over five years, though the absolute risk remains low. Experts advise regular eye exams for long-term users, particularly those with existing risk factors, rather than stopping the medication.
An observational study of 36,927 men aged 40+ found that regular tadalafil use over five years was associated with a higher glaucoma diagnosis rate (3.93% vs 3.16% in non-users), a 22% relative increase with an absolute difference of about 0.77 percentage points. The study cannot prove causation, and researchers note that the overall risk remains small; patients using tadalafil long-term should discuss eye monitoring with a clinician rather than stopping the medication.
A large observational study of about 74,000 men aged 40+ with lower urinary tract symptoms found long-term tadalafil use was associated with higher risks of glaucoma (22%), elevated intraocular pressure (32%), and primary open-angle glaucoma (33%) over up to five years, though causation cannot be established. The findings suggest regular eye monitoring for long-term Cialis users, especially those with glaucoma risk factors; patients should not stop the medication without medical advice.
An observational study of about 74,000 men aged 40+ over up to five years found tadalafil (Cialis) use for erectile dysfunction and enlarged-prostate symptoms was associated with a 22% higher risk of glaucoma, a 32% higher risk of elevated intraocular pressure, and a 33% higher risk of primary open-angle glaucoma versus nonusers. The study, published in the British Journal of Ophthalmology, cannot prove causation; researchers urge regular baseline eye exams for long‑term users, especially those with glaucoma risk factors.
Taiwanese study of nearly 37,000 men over 40 found daily tadalafil use for urinary symptoms associated with a 22% higher risk of developing glaucoma over five years versus non-users, and a higher risk of ocular hypertension. Absolute glaucoma incidence rose from 3.16% to 3.93% among users (about 0.77 percentage points). Although the overall risk remains small, doctors should monitor vision in patients prescribed PDE5 inhibitors, especially those with glaucoma risk factors, and more research is needed to understand the mechanism.
A large observational study of about 74,000 men aged 40+ found that tadalafil (Cialis), used for erectile dysfunction and urinary symptoms, was associated with a 22% higher risk of glaucoma (33% for primary open-angle glaucoma) and a 32% higher risk of ocular hypertension. The researchers caution that the design cannot prove causation, but regular eye exams may be advisable for users, especially those with predispositions, given widespread tadalafil use (millions of prescriptions in 2024).
A large observational study of 73,854 men found that long-term tadalafil use for urinary symptoms was associated with higher odds of glaucoma (22%), ocular hypertension (32%), and starting glaucoma treatment (33%) over five years, compared with non-users. While the study cannot prove causation and has limitations (e.g., limited ethnic diversity), researchers advise baseline eye exams and regular eye monitoring for long-term users, especially those with glaucoma risk factors.