Tag

Glaucoma

All articles tagged with #glaucoma

health1 day ago•2 min saved

Big Study Finds Long-Term Cialis Use May Increase Glaucoma Risk

A large observational study of about 74,000 men aged 40+ with lower urinary tract symptoms found long-term tadalafil use was associated with higher risks of glaucoma (22%), elevated intraocular pressure (32%), and primary open-angle glaucoma (33%) over up to five years, though causation cannot be established. The findings suggest regular eye monitoring for long-term Cialis users, especially those with glaucoma risk factors; patients should not stop the medication without medical advice.

via FOX 13 Tampa Bay|

#cialis #eye-health #glaucoma

health2 days ago•5 min saved

Large study links tadalafil use to higher glaucoma risk

An observational study of about 74,000 men aged 40+ over up to five years found tadalafil (Cialis) use for erectile dysfunction and enlarged-prostate symptoms was associated with a 22% higher risk of glaucoma, a 32% higher risk of elevated intraocular pressure, and a 33% higher risk of primary open-angle glaucoma versus nonusers. The study, published in the British Journal of Ophthalmology, cannot prove causation; researchers urge regular baseline eye exams for long‑term users, especially those with glaucoma risk factors.

via Fox News|

#cialis #eye-health #glaucoma

Popular ED Drug Linked to Small Increase in Glaucoma Risk

health7 days ago•2 min saved

ED Drug Cialis Linked to Higher Glaucoma Risk, Study Finds

A large observational study of about 74,000 men aged 40+ found that tadalafil (Cialis), used for erectile dysfunction and urinary symptoms, was associated with a 22% higher risk of glaucoma (33% for primary open-angle glaucoma) and a 32% higher risk of ocular hypertension. The researchers caution that the design cannot prove causation, but regular eye exams may be advisable for users, especially those with predispositions, given widespread tadalafil use (millions of prescriptions in 2024).

via New York Post|

#erectile-dysfunction #glaucoma #health

health13 days ago•6 min saved

Long-Term PDE5 Inhibitor Use Tied to Increased Glaucoma Risk

A large observational study of 73,854 men found that long-term tadalafil use for urinary symptoms was associated with higher odds of glaucoma (22%), ocular hypertension (32%), and starting glaucoma treatment (33%) over five years, compared with non-users. While the study cannot prove causation and has limitations (e.g., limited ethnic diversity), researchers advise baseline eye exams and regular eye monitoring for long-term users, especially those with glaucoma risk factors.

via SciTechDaily|

#eye-health #glaucoma #health

health20 days ago•11 min saved

ED drug tadalafil linked to higher glaucoma risk, study warns

A large observational study found long-term tadalafil use was associated with higher risks of glaucoma, ocular hypertension, and primary open-angle glaucoma over five years; the researchers caution that this does not prove causation and advise regular eye health monitoring for men on the drug, especially those with glaucoma risk factors or a family history.

via The Independent|

#eye-health #glaucoma #health

science1 month ago•57 min saved

Epigenetic Rejuvenation in the Eye Sets Stage for Reversing Blindness

Scientists report that epigenetic reprogramming to revive youthful cellular memory in aging eye cells has reached humans, with the first patient treated in a Phase 1 trial for glaucoma and other optic neuropathies. The approach could someday restore some lost vision, but safety, delivery, and how durable the effects are remain major hurdles before it becomes a widely available therapy.

via Yahoo|

#epigenetic-reprogramming #glaucoma #optic-nerve

science2 months ago•47 min saved

First-in-Human Gene Therapy Aims to Rewind Cellular Aging in Glaucoma

A Life Biosciences Phase 1 trial is testing ER-100, a gene therapy designed to reset the aging clock in eye cells using OSK (OCT4, SOX2, KLF4) to potentially restore vision in open-angle glaucoma. Early preclinical data suggest epigenetic restoration can improve cellular function, but the approach carries safety risks, including cancer, and it remains uncertain whether translating this to humans will succeed or be safe.

via Yahoo|

#epigenetic-restoration #gene-therapy #glaucoma

science2 months ago•2 min saved

First Human Trial Tests Rejuvenation of Aging Eye Cells for Glaucoma

Scientists have begun the first human trial of partial cellular reprogramming to nudge aging eye cells toward a younger state in hopes of regenerating optic nerve neurons to treat glaucoma. The study by Life Biosciences treated the first participant and plans to enroll up to 12 total; this is an early, experimental approach—not a lifespans therapy—with cancer risk as a key concern and no results yet.

via geekspin|

#aging #cellular-reprogramming #clinical-trial

science2 months ago•45 min saved

First human trial tests partial reprogramming to reverse aging in glaucoma

Scientists have treated the first participant in an early-stage clinical trial testing partial cellular reprogramming to make aging cells act younger, aiming to regenerate optic nerve neurons in glaucoma. While promising, the approach is experimental, enrolling up to 12 participants, with potential cancer risk, and is not a universal anti-aging therapy.

via Yahoo|

#aging #cellular-reprogramming #clinical-trial

health2 months ago•14 min saved

Aging Eyes: Simple Steps to Prevent Four Common Vision Threats

As people age, four common eye conditions—diabetic retinopathy, glaucoma, cataracts, and macular degeneration—rise in risk, but most vision loss can be prevented or delayed through regular eye exams (starting after age 45 or when diabetes is diagnosed), a healthy lifestyle, controlling blood pressure, diabetes, and cholesterol, protecting eyes from UV light, and timely treatments such as cataract surgery or glaucoma management; support and rehabilitation options are available for those with visual impairment.

via The Conversation|

#cataracts #diabetic-retinopathy #eye-health

science2 months ago•7 min saved

Eye-Aging Reprogramming Trial Doses First Patient in Vision Rescue Study

Life Biosciences dosed the first patient in a small, safety-focused trial of ER-100, a gene therapy designed to reset epigenetic marks in retinal ganglion cells to reverse aging-like changes and potentially restore vision in open-angle glaucoma or NAION. Delivered by a virus and activated by a specific antibiotic, the study will enroll up to 18 participants and follow them for years, attracting both optimism about aging biology and warnings about safety risks and uncertain efficacy.

via ScienceAlert|

#aging #er-100 #gene-therapy

science2 months ago•6 min saved

First patient treated in trial turning back cellular age to tackle glaucoma

The first participant has been treated in a landmark trial testing partial cellular reprogramming—activating three genes to make aged cells behave younger—in hopes of regenerating optic nerve neurons and treating glaucoma; safety is the primary focus, with low—but not zero—risk of cancer, and results will determine viability for broader use.

via Nature|

#aging #cellular-reprogramming #clinical-trial

life4 months ago•14 min saved

Eyes as Health Radar: 6 Clues Doctors Can Spot During a Checkup

Eye exams can uncover serious health problems beyond vision—retinal changes can reveal high blood pressure, glaucoma risk, and diabetic eye disease; doctors can also spot Demodex blepharitis and, if papilledema is present, possible brain tumors or masses, as well as inflammation signaling autoimmune disease. The piece stresses regular annual eye checkups and appropriate follow-ups, with treatments ranging from blood pressure and glucose control to specialized eyelid mite therapy and autoimmune workups as needed.

via HuffPost|

#demodex-blepharitis #diabetes #eye-health

health4 months ago•3 min saved

Sleeping Pillow-Free May Lower Eye Pressure in Glaucoma

A study of 144 glaucoma patients found that elevating the head with pillows raises intraocular pressure (IOP) and lowers ocular perfusion pressure (OPP) for many participants, suggesting neck position and jugular vein compression may affect eye drainage; sleeping flat or without a pillow could be a simple adjunct strategy to manage postural IOP, but the study is observational and not proof of causation; results varied by age and glaucoma type, requiring more research.

via SciTechDaily|

#glaucoma #health #intraocular-pressure