Lower Protein Intake Could Extend Healthy Aging, Large Review Suggests

A review of more than 350 studies finds that eating less protein can improve metabolic function, reduce inflammation and cellular damage, and activate pathways linked to healthier aging and longer life, especially for sedentary adults who may consume more protein than they actually need. While protein supports muscle with exercise, higher intake isn’t universally beneficial, and certain amino acids (like methionine, isoleucine, and valine) may drive aging when consumed in excess. The hormone FGF21 rises when protein is restricted and is thought to aid energy expenditure and glucose regulation. Protein needs vary by age and activity, suggesting personalized guidelines rather than a one-size-fits-all approach. The findings complement existing ideas about calorie restriction and highlight the importance of tailoring protein intake to individual lifestyles.