Extreme Keto in Mice Reverses Hyperglycemia and Boosts Training Response

A mouse study found that an extreme ketogenic diet normalized high blood sugar in hyperglycemic mice within a week, and after eight weeks of diet plus exercise, they showed improved VO2peak and muscle oxidative capacity. However, real exercise performance only improved when carbohydrates were reintroduced, suggesting a complex diet–exercise interaction. The findings are limited to mice, with human trials planned, and researchers caution that such extreme dieting isn’t suitable for everyone while Mediterranean-style approaches may be better for blood-sugar control.