Tag

Ketogenic Diet

All articles tagged with #ketogenic diet

health1 month ago•33 min saved

High LDL on keto isn’t risk-free: experts reaffirm LDL-apoB causality

A skeptical review of the lean mass hyper-responder (LMHR) hypothesis argues that very high LDL-C on a ketogenic diet does not erase the proven link between apoB-containing particles and atherosclerosis. It critiques two LMHR studies for short duration, lack of proper controls, and confounding factors, and questions the lipid-energy model’s validity. Across decades of evidence, LDL-C/apoB remains causally related to ASCVD, so reducing apoB—through diet, statins, or other therapies—remains the prudent course, even for metabolically healthy individuals. Longer-term, well-controlled data would be required to overturn this consensus.

via peterattiamd.com|

#apob #atherosclerosis #health

science2 months ago•4 min saved

Extreme Keto in Mice Reverses Hyperglycemia and Boosts Training Response

A mouse study found that an extreme ketogenic diet normalized high blood sugar in hyperglycemic mice within a week, and after eight weeks of diet plus exercise, they showed improved VO2peak and muscle oxidative capacity. However, real exercise performance only improved when carbohydrates were reintroduced, suggesting a complex diet–exercise interaction. The findings are limited to mice, with human trials planned, and researchers caution that such extreme dieting isn’t suitable for everyone while Mediterranean-style approaches may be better for blood-sugar control.

via ScienceAlert|

#blood-sugar #diabetes #exercise

health-and-medicine2 months ago•6 min saved

Ketogenic diet boosts exercise adaptation in hyperglycemic mice

In mice with high blood sugar, a high-fat ketogenic diet normalized blood sugar within a week and remodeled muscles to be more oxidative, improving oxygen use and endurance during exercise, suggesting diet and exercise may synergize to boost metabolic health—though human studies are needed and keto can be hard to maintain.

via ScienceDaily|

#exercise-performance #health-and-medicine #hyperglycemia

science2 months ago•8 min saved

Keto Diet Could Boost Exercise Benefits in Hyperglycemic Mice

A Nature Communications study in mice with high blood sugar found that a ketogenic diet lowered glucose, improved aerobic exercise adaptation, and aided skeletal-muscle remodeling when paired with training, suggesting glucose control may enhance exercise benefits. However, results are limited to animals, and applicability to humans is uncertain, with long-term sustainability and real-world effects needing further research.

via Medical News Today|

#aerobic-capacity #exercise #hyperglycemia

health3 months ago•52 min saved

A $50 glucose monitor and keto diet give relief from 18 years of migraines

After two decades of debilitating vestibular migraines, Rachel Weaver joined a clinical study that used affordable continuous glucose monitors (CGMs) to track glucose and found migraines rose with glucose spikes; participants followed a ketogenic diet with individualized carb ceilings—Weaver's around 50g/day—leading to a dramatic drop in symptoms. She’s now down to two migraine meds and reports a near reversal of her condition. The Frontiers in Neurology study of 247 migraine patients suggests CGMs and keto-like dietary strategies may help, but keto should be supervised and more data are needed.

via Daily Mail|

#clinical-trial #continuous-glucose-monitoring #health

health3 months ago•4 min saved

Experts push back on RFK Jr.'s keto claim to cure schizophrenia

Experts say RFK Jr.'s assertion that a ketogenic diet cures schizophrenia is not supported by solid evidence; the only hints come from two 2019 case reports by Harvard psychiatrist Christopher Palmer, which are uncontrolled and cannot establish efficacy. Ketosis may aid symptom remission in some cases, but medical supervision is essential and meds should not be stopped. Around 20 trials are exploring keto for psychiatric conditions, with research into mitochondria and brain activity; long-term adherence and cost pose practical challenges, so no cure is proven yet.

via The Guardian|

#case-reports #christopher-palmer #health

health3 months ago•5 min saved

Harvard Psychiatrist Refutes Kennedy Keto-Cure Claim for Schizophrenia

Harvard psychiatrist Christopher Palmer said Kennedy Jr.’s claim that keto diets cure schizophrenia is not accurate; while ketogenic therapy shows promise for some patients, it remains unproven and should not replace antipsychotics without medical supervision. Palmer envisions a future where dietary interventions could play a role, with ongoing trials and funding, as Kennedy’s MAHA movement promotes broader research and access to metabolic treatments.

via The New York Times|

#health #ketogenic-diet #make-america-healthy-again

science3 months ago•4 min saved

Mice on Keto Diet Show Hidden Metabolic Trade-Offs

University of Utah researchers fed mice four diets for nine months; those on a keto-style high-fat, low-carb diet gained less weight than a Western high-fat diet but developed fatty liver and impaired liver function in males, with both sexes showing reduced blood glucose and insulin due to impaired pancreatic insulin production. The effects reversed after stopping the diet, but human relevance remains unproven, underscoring potential metabolic trade-offs of ketosis beyond epilepsy uses.

via ScienceAlert|

#fatty-liver #insulin-regulation #ketogenic-diet

health-and-medicine3 months ago•8 min saved

Long-term ketogenic diet linked to liver and sugar problems in mice

In a nine-month-plus mouse study, a ketogenic diet prevented weight gain but caused fatty liver, dyslipidemia, and impaired insulin secretion, leading to poor blood-sugar control after carbohydrate reintroduction; effects were more severe in male mice, though some metabolic damage appeared reversible after stopping keto.

via ScienceDaily|

#fatty-liver-disease #glucose-intolerance #health-and-medicine

health7 months ago•3 min saved

Keto Diet May Help Maintain Brain Youthfulness, Especially in Women

Researchers at the University of Missouri have found that a high-fat, low-carb ketogenic diet may support long-term brain health and potentially prevent cognitive decline, especially in individuals with the APOE4 gene linked to Alzheimer's, with effects varying by gender. The diet appears to improve gut bacteria and brain energy levels, offering a promising avenue for personalized nutrition strategies to preserve cognitive function.

via Science Daily|

#alzheimers #brain-health #genetics

health7 months ago•6 min saved

Ketogenic Diet Significantly Reduces Depression Symptoms in Pilot Study

A small pilot study found that a well-formulated ketogenic diet significantly reduced depression symptoms by about 70% in college students with major depressive disorder, alongside improvements in physical health and cognitive function, suggesting potential as an adjunct treatment for depression.

via PsyPost|

#clinical-trial #depression #health

health1 year ago•5 min saved

Boosting CAR-T Therapy with the Ketogenic Diet

A study from the University of Pennsylvania suggests that a ketogenic diet enhances the effectiveness of CAR T cell therapy in treating lymphoma by utilizing beta-hydroxybutyrate (BHB) as a preferred energy source over glucose. This approach led to improved tumor control and survival in mice, with translational studies indicating similar benefits in human samples. A Phase I clinical trial is underway to test BHB supplementation in lymphoma patients, potentially offering a low-toxicity, cost-effective strategy to boost cancer immunotherapy outcomes.

via Neuroscience News|

#beta-hydroxybutyrate #cancer-treatment #car-t-cell-therapy

health2 years ago•5 min saved

"Study Warns Keto Diet May Harm Heart and Kidneys"

A study by UTHealth San Antonio found that ketogenic diets may accelerate cellular aging in mice, particularly affecting the heart and kidneys. The research suggests that while keto diets can aid in weight loss and manage epilepsy, they may pose long-term health risks, emphasizing the need for human trials to fully understand these effects. Experts recommend medical guidance for those considering such diets.

via AOL|

#cellular-aging #health #heart-health

health2 years ago•5 min saved

New Study: Keto Diet May Harm Health and Accelerate Aging

A study by UTHealth San Antonio found that ketogenic diets may accelerate cellular aging in mice, particularly affecting the heart and kidneys. The research suggests that while keto diets can aid in weight loss and manage epilepsy, they may pose long-term health risks, emphasizing the need for careful consideration and medical guidance. Further human trials are necessary to fully understand the diet's long-term effects.

via Medical News Today|

#cellular-aging #health #heart-health

health2 years ago•10 min saved

Lifestyle Changes Show Promise in Reversing Alzheimer's Symptoms

Dr. Heather Sandison, a naturopathic doctor, claims that a six-step lifestyle protocol involving diet, exercise, stress reduction, and toxin avoidance has reversed Alzheimer's symptoms in some patients. Her book, "Reversing Alzheimer’s The New Toolkit to Improve Cognition and Protect Brain Health," details cases of significant cognitive improvement. However, conventional medical experts remain skeptical, citing a lack of rigorous scientific evidence and the unrealistic nature of such claims.

via Daily Mail|

#alzheimers #cognitive-health #health