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Ketogenic Diet

All articles tagged with #ketogenic diet

Extreme Keto in Mice Reverses Hyperglycemia and Boosts Training Response
science24 days ago

Extreme Keto in Mice Reverses Hyperglycemia and Boosts Training Response

A mouse study found that an extreme ketogenic diet normalized high blood sugar in hyperglycemic mice within a week, and after eight weeks of diet plus exercise, they showed improved VO2peak and muscle oxidative capacity. However, real exercise performance only improved when carbohydrates were reintroduced, suggesting a complex diet–exercise interaction. The findings are limited to mice, with human trials planned, and researchers caution that such extreme dieting isn’t suitable for everyone while Mediterranean-style approaches may be better for blood-sugar control.

Ketogenic diet boosts exercise adaptation in hyperglycemic mice
health-and-medicine1 month ago

Ketogenic diet boosts exercise adaptation in hyperglycemic mice

In mice with high blood sugar, a high-fat ketogenic diet normalized blood sugar within a week and remodeled muscles to be more oxidative, improving oxygen use and endurance during exercise, suggesting diet and exercise may synergize to boost metabolic health—though human studies are needed and keto can be hard to maintain.

Keto Diet Could Boost Exercise Benefits in Hyperglycemic Mice
science1 month ago

Keto Diet Could Boost Exercise Benefits in Hyperglycemic Mice

A Nature Communications study in mice with high blood sugar found that a ketogenic diet lowered glucose, improved aerobic exercise adaptation, and aided skeletal-muscle remodeling when paired with training, suggesting glucose control may enhance exercise benefits. However, results are limited to animals, and applicability to humans is uncertain, with long-term sustainability and real-world effects needing further research.

A $50 glucose monitor and keto diet give relief from 18 years of migraines
health1 month ago

A $50 glucose monitor and keto diet give relief from 18 years of migraines

After two decades of debilitating vestibular migraines, Rachel Weaver joined a clinical study that used affordable continuous glucose monitors (CGMs) to track glucose and found migraines rose with glucose spikes; participants followed a ketogenic diet with individualized carb ceilings—Weaver's around 50g/day—leading to a dramatic drop in symptoms. She’s now down to two migraine meds and reports a near reversal of her condition. The Frontiers in Neurology study of 247 migraine patients suggests CGMs and keto-like dietary strategies may help, but keto should be supervised and more data are needed.

Experts push back on RFK Jr.'s keto claim to cure schizophrenia
health1 month ago

Experts push back on RFK Jr.'s keto claim to cure schizophrenia

Experts say RFK Jr.'s assertion that a ketogenic diet cures schizophrenia is not supported by solid evidence; the only hints come from two 2019 case reports by Harvard psychiatrist Christopher Palmer, which are uncontrolled and cannot establish efficacy. Ketosis may aid symptom remission in some cases, but medical supervision is essential and meds should not be stopped. Around 20 trials are exploring keto for psychiatric conditions, with research into mitochondria and brain activity; long-term adherence and cost pose practical challenges, so no cure is proven yet.

Harvard Psychiatrist Refutes Kennedy Keto-Cure Claim for Schizophrenia
health2 months ago

Harvard Psychiatrist Refutes Kennedy Keto-Cure Claim for Schizophrenia

Harvard psychiatrist Christopher Palmer said Kennedy Jr.’s claim that keto diets cure schizophrenia is not accurate; while ketogenic therapy shows promise for some patients, it remains unproven and should not replace antipsychotics without medical supervision. Palmer envisions a future where dietary interventions could play a role, with ongoing trials and funding, as Kennedy’s MAHA movement promotes broader research and access to metabolic treatments.

Mice on Keto Diet Show Hidden Metabolic Trade-Offs
science2 months ago

Mice on Keto Diet Show Hidden Metabolic Trade-Offs

University of Utah researchers fed mice four diets for nine months; those on a keto-style high-fat, low-carb diet gained less weight than a Western high-fat diet but developed fatty liver and impaired liver function in males, with both sexes showing reduced blood glucose and insulin due to impaired pancreatic insulin production. The effects reversed after stopping the diet, but human relevance remains unproven, underscoring potential metabolic trade-offs of ketosis beyond epilepsy uses.

Long-term ketogenic diet linked to liver and sugar problems in mice
health-and-medicine2 months ago

Long-term ketogenic diet linked to liver and sugar problems in mice

In a nine-month-plus mouse study, a ketogenic diet prevented weight gain but caused fatty liver, dyslipidemia, and impaired insulin secretion, leading to poor blood-sugar control after carbohydrate reintroduction; effects were more severe in male mice, though some metabolic damage appeared reversible after stopping keto.

Keto Diet May Help Maintain Brain Youthfulness, Especially in Women
health5 months ago

Keto Diet May Help Maintain Brain Youthfulness, Especially in Women

Researchers at the University of Missouri have found that a high-fat, low-carb ketogenic diet may support long-term brain health and potentially prevent cognitive decline, especially in individuals with the APOE4 gene linked to Alzheimer's, with effects varying by gender. The diet appears to improve gut bacteria and brain energy levels, offering a promising avenue for personalized nutrition strategies to preserve cognitive function.

Boosting CAR-T Therapy with the Ketogenic Diet
health1 year ago

Boosting CAR-T Therapy with the Ketogenic Diet

A study from the University of Pennsylvania suggests that a ketogenic diet enhances the effectiveness of CAR T cell therapy in treating lymphoma by utilizing beta-hydroxybutyrate (BHB) as a preferred energy source over glucose. This approach led to improved tumor control and survival in mice, with translational studies indicating similar benefits in human samples. A Phase I clinical trial is underway to test BHB supplementation in lymphoma patients, potentially offering a low-toxicity, cost-effective strategy to boost cancer immunotherapy outcomes.

"Study Warns Keto Diet May Harm Heart and Kidneys"
health1 year ago

"Study Warns Keto Diet May Harm Heart and Kidneys"

A study by UTHealth San Antonio found that ketogenic diets may accelerate cellular aging in mice, particularly affecting the heart and kidneys. The research suggests that while keto diets can aid in weight loss and manage epilepsy, they may pose long-term health risks, emphasizing the need for human trials to fully understand these effects. Experts recommend medical guidance for those considering such diets.

New Study: Keto Diet May Harm Health and Accelerate Aging
health1 year ago

New Study: Keto Diet May Harm Health and Accelerate Aging

A study by UTHealth San Antonio found that ketogenic diets may accelerate cellular aging in mice, particularly affecting the heart and kidneys. The research suggests that while keto diets can aid in weight loss and manage epilepsy, they may pose long-term health risks, emphasizing the need for careful consideration and medical guidance. Further human trials are necessary to fully understand the diet's long-term effects.

Lifestyle Changes Show Promise in Reversing Alzheimer's Symptoms
health1 year ago

Lifestyle Changes Show Promise in Reversing Alzheimer's Symptoms

Dr. Heather Sandison, a naturopathic doctor, claims that a six-step lifestyle protocol involving diet, exercise, stress reduction, and toxin avoidance has reversed Alzheimer's symptoms in some patients. Her book, "Reversing Alzheimer’s The New Toolkit to Improve Cognition and Protect Brain Health," details cases of significant cognitive improvement. However, conventional medical experts remain skeptical, citing a lack of rigorous scientific evidence and the unrealistic nature of such claims.

"Ketogenic Diet's Potential for Severe Mental Illness: What You Need to Know"
health2 years ago

"Ketogenic Diet's Potential for Severe Mental Illness: What You Need to Know"

A pilot study from Stanford Medicine suggests that a ketogenic diet, when combined with standard medication, may improve both metabolic health and psychiatric symptoms in people with severe mental illnesses such as bipolar disorder and schizophrenia. The study found that participants who strictly adhered to the ketogenic diet showed improvements in psychiatric symptoms, metabolic markers, and overall quality of life. However, experts emphasize the need for more comprehensive research and caution against the long-term sustainability and potential side effects of the ketogenic diet, recommending more sustainable dietary patterns and close monitoring by healthcare professionals.