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Metformin’s brain pathway unlocked: Rap1 in the hypothalamus drives glucose control

1 min read
Source: ScienceDaily
Metformin’s brain pathway unlocked: Rap1 in the hypothalamus drives glucose control
Photo: ScienceDaily
TL;DR

Scientists reveal metformin lowers blood sugar by acting in the brain, specifically by suppressing Rap1 in the ventromedial hypothalamus and activating SF1 neurons, with brain effects at far lower drug levels than previously thought, opening possibilities for brain-targeted diabetes therapies and potential brain-health benefits.

Topics:healthscience#brain#glucose#hypothalamus#metformin#rap1#science
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  1. Metformin’s hidden brain pathway revealed after 60 years  ScienceDaily
  2. After 60 Years, Diabetes Drug Revealed to Unexpectedly Affect The Brain  ScienceAlert
  3. How metformin, the diabetes drug, affects brain activity  NewsBytes
  4. Metformin treated diabetes for 60 years. Now scientists find it works in the brain too  Futura, Le média qui explore le monde
  5. A 60-Year-Old Diabetes Drug Just Revealed Astonishing Effects on the Brain  Iowa Park Leader

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