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A mole-rat longevity gene extends lifespan and boosts cancer resistance in mice

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Source: Space Daily
A mole-rat longevity gene extends lifespan and boosts cancer resistance in mice
Photo: Space Daily
TL;DR Summary

Engineered mice carrying the naked mole rat Has2 gene overproduced high‑molecular‑mass hyaluronan, modestly extending median lifespan (~4.4%), reducing inflammation, improving gut barrier, and increasing resistance to tumours—demonstrating a transferable longevity mechanism rather than a universal therapy.

Topics:science#cancer-resistance#has2#hyaluronan#longevity#naked-mole-rat#science
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Scientists took one of the naked mole rat’s longevity tricks — a gene that helps it produce unusually protective hyaluronan — and put it into mice. The result: the mice lived longer, had less inflammation, and were more resistant to tumours.  Space Daily

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