All articles tagged with #aptamers
Researchers at Mayo Clinic used DNA aptamers to selectively bind proteins on senescent cells, tagging these 'zombie' cells in mouse tissues and enabling their identification amid healthy cells. The study suggests aptamers could become a cost-effective tool for detecting senescent cells and may eventually enable targeted therapies, though applicability to humans remains to be shown.
Researchers at Mayo Clinic developed a new method using aptamers to label and potentially target senescent cells, which are linked to aging and diseases like cancer and Alzheimer's. This innovative approach, sparked by a student collaboration, could lead to better detection and treatment of age-related conditions in humans.
Mayo Clinic researchers developed a new method using DNA-based aptamers to identify 'zombie' senescent cells linked to aging and diseases like cancer and Alzheimer's, potentially paving the way for targeted therapies.
Researchers have created a 3D architecture of a DNA mimic of green fluorescent protein (GFP) using lettuce RNA aptamers. The mimic, called Lettuce–DFHBI-1T, has a complex structure that includes a four-way junction and a G-quadruplex. The structure could be used to develop new RNA aptamers for imaging and detecting RNA in living cells.