Tag

Asundexian

All articles tagged with #asundexian

Diet, vaccine, and drug linked to lower stroke risk in new studies
health1 month ago

Diet, vaccine, and drug linked to lower stroke risk in new studies

Three new studies suggest potential stroke-prevention strategies: a Mediterranean-style diet may lower risk of ischemic and hemorrhagic stroke in women; the shingles vaccine was associated with fewer major adverse cardiac events in people with ASCVD in an observational study (not yet peer-reviewed, so causality isn’t established); and the oral anticoagulant asundexian may reduce secondary ischemic stroke risk in patients who’ve had a prior stroke or high‑risk TIA by inhibiting factor XIa. Stroke is a leading cause of death, with many events potentially preventable through lifestyle and medical interventions.

"Bayer's Troubles Mount: OCEANIC-AF Study Halted, Drug Setback and Restructuring Considered"
healthcare2 years ago

"Bayer's Troubles Mount: OCEANIC-AF Study Halted, Drug Setback and Restructuring Considered"

Bayer's phase III OCEANIC-AF study, comparing asundexian to apixaban in patients with atrial fibrillation at risk for stroke, is being stopped early due to the recommendation of the study's Independent Data Monitoring Committee (IDMC) citing inferior efficacy of asundexian compared to the control arm. Safety data remains consistent with previous reports, and Bayer will analyze the data further. The OCEANIC-STROKE study will continue as planned, and measures will be taken to close the OCEANIC-AF study. Asundexian is an investigational agent and has not been approved for use by any health authority.