Tag

Cellular Damage

All articles tagged with #cellular damage

science21 days ago•36 min saved

Orange pigment may guard cells, solving the puzzle of redheads and orange birds

A CSIC study of 65 zebra finches shows the orange pigment pheomelanin is made from cysteine and can help cells handle excess cysteine, reducing oxidative damage. In males, cysteine supplementation combined with a pheomelanin blocker raised a blood damage marker (malondialdehyde) versus cysteine alone, while females lacking pheomelanin did not show this protective effect, suggesting pigment production helps excrete excess cysteine. The findings offer a cellular rationale for why orange/red coloration persists evolutionarily and imply environment and diet may influence pigmentation-related health risks in humans; researchers plan to explore whether human skin uses a similar cysteine-handling route.

via Earth.com|

#cellular-damage #cysteine #evolution

medical-research2 years ago•96 min saved

The Role of Iron Accumulation in Fibrosis and Senescence

Iron accumulation has been found to play a causative role in fibrogenesis, senescence, and the senescence-associated secretory phenotype (SASP). Fibrogenic injuries can lead to progressive iron accumulation in tissues, which promotes the secretion of pro-fibrotic cytokines, recruitment of immune cells, remodeling of the extracellular matrix, and activation of profibrogenic pathways. Iron accumulation also induces cellular senescence, characterized by the upregulation of senescence markers and DNA damage. These findings suggest that targeting iron accumulation may be a potential therapeutic strategy for fibrotic diseases.

via Nature.com|

#cellular-damage #fibrogenesis #fibrosis

health3 years ago•2 min saved

Expert recommends anti-inflammatory foods for longevity boost.

Nutritionist Daniel Herman recommends eating leafy greens, berries, nuts, whole grains, and fatty fish to reduce chronic inflammation, protect against cellular damage, and boost longevity. These foods are rich in antioxidants, fiber, vitamins, and minerals that help to lower inflammation, improve digestion, and reduce the risk of chronic diseases like heart disease, diabetes, cancer, and Alzheimer's. Eating a handful of nuts a day, consuming whole grain foods, and adding fatty fish to your diet can provide the body with important nutrients and antioxidants that promote healthy aging.

via Express|

#anti-inflammatory-foods #antioxidants #cellular-damage