Tag

Cysteine

All articles tagged with #cysteine

Orange-hued hair may shield cells by balancing cysteine, study finds
science1 month ago

Orange-hued hair may shield cells by balancing cysteine, study finds

New research shows the orange-red pigment pheomelanin, which creates orange hair in humans and birds, may protect health by lowering excess cysteine in cells, reducing potential damage. In a zebra finch experiment, birds given cysteine alongside a blocker of pheomelanin synthesis (ML349) showed more cellular damage, while pheomelanin production helped balance cysteine levels. This provides the first experimental evidence of a physiological role for pheomelanin and may shed light on melanoma risk factors linked to pheomelanin-related traits.

Orange pigment may guard cells, solving the puzzle of redheads and orange birds
science3 months ago

Orange pigment may guard cells, solving the puzzle of redheads and orange birds

A CSIC study of 65 zebra finches shows the orange pigment pheomelanin is made from cysteine and can help cells handle excess cysteine, reducing oxidative damage. In males, cysteine supplementation combined with a pheomelanin blocker raised a blood damage marker (malondialdehyde) versus cysteine alone, while females lacking pheomelanin did not show this protective effect, suggesting pigment production helps excrete excess cysteine. The findings offer a cellular rationale for why orange/red coloration persists evolutionarily and imply environment and diet may influence pigmentation-related health risks in humans; researchers plan to explore whether human skin uses a similar cysteine-handling route.

Low Methionine and Cysteine Diet Sparks Fat Burning in Mice
health-and-medicine5 months ago

Low Methionine and Cysteine Diet Sparks Fat Burning in Mice

Reducing two amino acids common in animal protein—methionine and cysteine—in mice boosted energy expenditure by about 20% via beige fat, causing weight loss without changing food intake or activity, and was comparable to constant cold exposure, suggesting diet alone could activate fat-burning pathways, though human relevance remains unproven and further work on safety and applicability is needed.

MIT Scientists Find Rejuvenating Amino Acid for the Gut
health10 months ago

MIT Scientists Find Rejuvenating Amino Acid for the Gut

MIT researchers discovered that a diet high in the amino acid cysteine can activate immune pathways that promote stem cell regeneration in the small intestine, potentially aiding in tissue repair after radiation or chemotherapy damage. The study, conducted in mice, suggests that increasing cysteine intake through diet or supplements could enhance intestinal healing, with implications for cancer treatment recovery.