Tag

Doacs

All articles tagged with #doacs

health13 days ago•16 min saved

Watchman FLX Noninferior to DOACs in AF, but With Important Caveats

CHAMPION-AF showed that left atrial appendage occlusion with the Watchman FLX was noninferior to direct oral anticoagulants for a three-year composite of cardiovascular death, stroke, and systemic embolism in AF patients eligible for anticoagulation, and it reduced clinically relevant nonprocedural bleeding. However, the trial had low event rates, a signal of more ischemic strokes in the device arm, and questions about periprocedural bleeding and applicability, which means LAAO should be considered as an option in shared decision-making rather than a universal substitute for NOACs. Longer-term data from ongoing trials will help clarify its role in high-risk AF.

via tctmd.com|

#atrial-fibrillation #champion-af #doacs

cardiology1 month ago•11 min saved

New Multisociety Guideline Uses Five Acute PE Categories to Guide Care

A new joint ACC/AHA/peer-society guideline for evaluating and managing acute pulmonary embolism in adults introduces five Acute PE Clinical Categories (A–E) to stratify severity and guide therapy across emergency, inpatient, and post-acute settings. It recommends low-molecular-weight heparin over unfractionated heparin for initial anticoagulation, favors direct oral anticoagulants over vitamin K antagonists when appropriate, and supports continuing anticoagulation beyond 3–6 months for selected patients; it also emphasizes PE response teams (PERTs) and notes future evidence gaps.

via American College of Cardiology|

#acute-pulmonary-embolism #anticoagulation #cardiology

health1 month ago•2 min saved

2026 Acute PE Guideline Introduces Five-Category Risk System to Guide Management

The 2026 AHA/ACC guideline for acute PE introduces a five-category Acute PE Clinical Categories system (A–E) to sharpen risk stratification and guide therapy; patients with higher risk (categories C–E) or cardiopulmonary failure should be hospitalized, and for those eligible for oral anticoagulation, direct oral anticoagulants are preferred over vitamin K antagonists to prevent recurrent VTE and reduce major bleeding.

via professional.heart.org|

#anticoagulation #doacs #guidelines

health2 years ago•5 min saved

Blood Thinners: Lowering Dementia Risk in AFib Patients

The use of direct oral anticoagulants (DOACs) instead of warfarin, a traditional blood thinner, is associated with a significantly lower risk of dementia in Asian populations receiving treatment for atrial fibrillation (AFib), according to a new study. The risk of dementia in those treated with DOACs was 12% lower than in those treated with warfarin. However, this lower incidence of dementia did not apply to other populations. The study suggests that DOACs may help prevent vascular dementia caused by mini-blood clots in the brain. While DOACs offer advantages over warfarin, such as not requiring dietary restrictions or regular blood tests, they are more expensive and lack a readily accessible antidote. The study highlights the need for further research to determine the applicability of these findings to different populations.

via Medical News Today|

#atrial-fibrillation #blood-thinners #dementia