Tag

Duodenal Mucosal Resurfacing

All articles tagged with #duodenal mucosal resurfacing

health1 month ago•7 min saved

Beyond GLP-1: Endoscopic and Oral Options to Sustain Weight Loss

Real-world data show weight loss from GLP-1 therapy is often not sustained after discontinuation, with most patients regaining weight and metabolic benefits fading within about 1.4 years. Emerging strategies—endoscopic approaches such as endoscopic sleeve gastroplasty, duodenal mucosal resurfacing, and the newly approved oral GLP-1 orforglipron—offer potential for longer-term maintenance, but cost, insurance coverage, and access remain barriers. When cost is considered, bariatric surgery can be more cost-effective long term; more head-to-head studies and guidelines are needed to define optimal maintenance after GLP-1 therapy.

via Medscape|

#duodenal-mucosal-resurfacing #endoscopic-sleeve-gastroplasty #glp-1

health2 months ago•26 min saved

Endoscopic gut reset could sustain GLP-1 weight loss after stopping the meds

A new outpatient endoscopic procedure called duodenal mucosal resurfacing (DMR) may help people maintain GLP-1–driven weight loss after stopping the meds. In a 45-patient study, those treated with DMR regained about 7 pounds on average (roughly 80% of their weight loss), while a sham group regained about 14 pounds; participants also reported reduced cravings and no serious complications, suggesting a durable metabolic reset that could extend weight-loss benefits beyond GLP-1 therapy. Results will be presented at Digestive Diseases Week 2026.

via New York Post|

#duodenal-mucosal-resurfacing #endoscopy #glp-1

health2 months ago•4 min saved

Gut Reset May Sustain Weight Loss After GLP-1 Treatments

A blinded, sham-controlled trial presented at DDW 2026 suggests duodenal mucosal resurfacing, an outpatient endoscopic gut-reset procedure, may help maintain weight loss after stopping GLP-1 drugs like ozempic/semaglutide. In 45 participants who had previously lost at least 15% body weight on tirzepatide, those who received the actual resurfacing regained about 7 pounds on average over six months, preserving over 80% of their initial weight loss, while controls (sham) regained far more. The procedure appeared safe with quick recovery; larger REMAIN-1 data are pending, with topline six-month results expected in late 2026, potentially offering a post-drug maintenance option if confirmed.

via SciTechDaily|

#duodenal-mucosal-resurfacing #glp-1 #gut

health2 months ago•261 min saved

Endoscopic gut reset may lock in GLP-1 weight loss after stopping meds

A minimally invasive endoscopic procedure called duodenal mucosal resurfacing may help people maintain weight loss after discontinuing GLP-1 diabetes/weight-loss drugs. In a six‑month follow‑up of 45 participants (29 treated, 16 sham) who had at least 15% weight loss on tirzepatide, the procedure group regained about seven pounds and kept over 80% of their drug‑induced weight loss, while the sham group regained more, suggesting a durable metabolic reset observed at Digestive Disease Week 2026.

via AOL.com|

#duodenal-mucosal-resurfacing #glp-1-drugs #health

health-and-medicine2 months ago•6 min saved

Endoscopic gut reset shows promise to preserve weight loss after GLP-1 therapy

A blinded, sham-controlled trial presented at DDW 2026 suggests that duodenal mucosal resurfacing, a minimally invasive endoscopic procedure, may help people retain most of their GLP-1–driven weight loss after stopping Ozempic/semaglutide. In the early REMAIN-1 data (45 participants: 29 treated, 16 sham), those who received resurfacing regained significantly less weight than controls six months after discontinuing the drug, with some patients regaining as little as ~7 pounds and keeping over 80% of their weight loss; no serious complications were reported and recovery is quick. The regimen is investigational, with larger topline results from REMAIN-1 anticipated later in 2026.

via Science Daily|

#duodenal-mucosal-resurfacing #health-and-medicine #minimally-invasive-procedure