All articles tagged with #metabolic adaptation
Louisiana researchers at Pennington Biomedical Center, led by Dr. Eric Ravussin, are studying how GLP-1 weight‑loss drugs affect metabolism and muscle mass, including resting metabolic rate and energy expenditure in a metabolic chamber to understand metabolic adaptation that can slow weight loss, while clinicians emphasize adequate protein and exercise to minimize muscle loss as these therapies evolve.
While exercise has limited impact on initial weight loss due to factors like increased appetite and metabolic adaptation, it plays a crucial role in maintaining weight loss and improving overall health, including better cholesterol, blood sugar control, and mental well-being.
The article emphasizes that weight loss is complex, influenced by biology, genetics, environment, and socioeconomic factors, and not solely a matter of willpower or calorie counting. It highlights biological responses like metabolic adaptation that make weight loss challenging, stresses the importance of focusing on overall health rather than just weight, and advocates for sustainable lifestyle changes over fad diets. Exercise benefits health regardless of weight change, and improving health markers can occur without weight loss.
Eggs of the Aedes mosquito, which carries the Zika virus, have been found to survive desiccation by altering their metabolism, according to a study. Researchers discovered that the eggs undergo changes in metabolic pathways, including an increase in lipid metabolism and a decrease in glycolysis and ATP production. The eggs also accumulate polyamines, which help protect cellular components. Inhibitors of polyamine synthesis and fatty acid metabolism reduced the eggs' ability to survive desiccation. These findings provide insights into controlling the spread of the Zika-carrying mosquito and suggest potential vector-control agents.