Tag

Raman Spectroscopy

All articles tagged with #raman spectroscopy

science1 month ago•5 min saved

CO2-injected cement gains early strength via a transient silica gel network

MIT researchers used Raman spectroscopy to watch CO2-injected cement paste undergo a three-stage reaction: quick calcium carbonate formation slows hydration, a transient silica gel forms and disperses through the paste, and as the gel is consumed, a more evenly distributed calcium silicate hydrate binder forms, yielding about 13% higher compressive strength at 24 hours with 1% CO2 by weight. This mechanism helps explain the strength boost of CO2-injected cement and points to potential emissions offsets, though dosage must be carefully managed to avoid premature carbonate locking.

via MIT News|

#calcium-silicate-hydrate #co2-injected-cement #early-age-strength

technology1 month ago•11 min saved

No Pricks, Big Hopes: The Quest for Noninvasive Glucose in Wearables

Researchers continue to chase truly noninvasive glucose monitoring for wearables, a notoriously difficult problem because glucose signals are small and easily swamped by other biological signals. The effort has shifted from tear-based sensors (which proved unreliable) to methods that detect glucose through the skin, with Raman spectroscopy showing promise but requiring highly sensitive, bulky optics. MIT researchers have developed a working shoebox-sized prototype that reads skin glucose signals and aims to miniaturize it for wearables, with a startup partner planning market release around 2029–2030 after FDA clearance. The path to a consumer device like an Apple Watch remains long due to the need for medical-grade accuracy and substantial miniaturization, but progress continues on narrowing the signal-to-noise gap and shrinking the technology for everyday use.

via Gizmodo|

#biomedical-engineering #glucose-monitoring #noninvasive

science2 months ago•5 min saved

Ink in Martian Meteorites Triggers Contamination Wake-Up Call for Space Sample Prep

Researchers analyzing Martian meteorites found ballpoint pen ink contamination likely introduced during Earth-based handling, highlighting contamination risks in planetary sample prep and underscoring the need for standardized, contamination-aware protocols as space missions return Martian material.

via The Daily Galaxy|

#contamination #martian-meteorites #planetary-science

health7 months ago•4 min saved

Noninvasive Imaging May Replace Finger Pricks for Diabetes Testing

MIT researchers have developed a noninvasive, Raman spectroscopy-based device that can measure blood glucose levels without finger pricks, showing promise as a comfortable alternative for diabetes management, with ongoing efforts to miniaturize and adapt it for wearable use.

via MIT News|

#diabetes #glucose-monitoring #health

science-and-technology2 years ago•3 min saved

Revolutionary Spectroscopy Technique Shatters 50 Years of Frustration

Researchers from Texas A&M University and TEES have developed a new technique called thermostable-Raman-interaction-profiling (TRIP) that overcomes the limitations of Raman spectroscopy in damaging live proteins during optical measurements. TRIP allows low-concentration, low-dose screenings for protein-to-ligand interactions in physiologically relevant conditions, enabling label-free, highly reproducible measurements. This breakthrough has potential applications in rapid and cost-effective drug, vaccine, and virus testing, as well as DNA analysis. The TRIP technique offers real-time detection of protein-ligand interactions, shortening the timeline for testing and providing accurate results. Additionally, the TRIP method requires smaller sample sizes and lower protein concentrations, making it a more cost-effective process.

via SciTechDaily|

#biomedical-research #drug-testing #protein-ligand-interactions

science-and-technology2 years ago•5 min saved

"Rapid Pathogen Detection Enabled by Magnetic Beads' Optical Signal"

Researchers at MIT have discovered that Dynabeads, antibody-coated superparamagnetic beads, have a strong Raman signature that can be used to quickly detect pathogens in various diagnostic tests. By using Raman spectroscopy, the researchers were able to confirm the presence of Dynabead-bound pathogens within less than an hour, providing a rapid and reliable method for detecting contaminants such as Salmonella. The team is now working on developing a portable device for detecting bacterial pathogens, which could have significant applications in healthcare and resource-limited environments.

via Phys.org|

#diagnostic-tests #dynabeads #magnetic-beads

science3 years ago•25 min saved

Comparing enamel composition in pigmented and unpigmented teeth using high-resolution Raman spectroscopy

High-resolution Raman spectroscopy was used to analyze the compositional differences between pigmented incisor enamel (PIE) and unpigmented molar enamel (UME) in rats. The study found that PIE had higher levels of iron, higher mineral crystallinity, and higher acid phosphate and hydroxyl levels compared to UME. The enamel prisms in PIE were also wider and longer than those in UME. These findings provide new insights into enamel biomineralization and highlight the differences in ameloblast function between incisors and molars in rodents.

via Nature.com|

#dental-enamel #enamel-composition #incisor-enamel

science-and-technology3 years ago•3 min saved

"Revolutionary Raman Breakthrough Ends Decades of Frustration"

Researchers at Texas A&M University have developed a new technique called thermostable-Raman-interaction-profiling (TRIP) that overcomes the limitations of Raman spectroscopy in studying live proteins. By cooling the surface or substrate, the proteins remain intact during optical measurements, leading to highly reproducible results. This breakthrough has significant implications for drug and vaccine testing, as well as clinical diagnostics, by shortening the timeline and improving accuracy. The TRIP technique also requires smaller sample sizes and lower protein concentrations, making it a more cost-effective process. Future applications may include DNA analysis and other biological molecules.

via Phys.org|

#biomedical-research #drug-and-vaccine-testing #protein-ligand-interactions