Tag

Transplant Medicine

All articles tagged with #transplant medicine

science1 month ago•4 min saved

New Antibodies Targeting EBV Proteins Show Promise in Preventing Infection in Mice

Researchers at the Fred Hutchinson Cancer Center and the University of Washington developed ten new antibodies targeting two Epstein-Barr virus (EBV) surface proteins, gp350 and gp42. In mouse models with human-like immune systems, one antibody successfully prevented EBV infection. This approach addresses the difficulty of finding specific immune responses to EBV, which infects nearly all B cells. The findings, published in Cell Reports Medicine, suggest potential future applications in preventing post-transplant lymphoproliferative disorders (PTLD) in immunosuppressed patients, particularly children, though human clinical trials are still pending.

via ScienceAlert|

#antibody-development #b-cell-infection #epstein-barr-virus

science1 month ago•11 min saved

Wood Frog Freeze-Tolerance Techniques Extend Human Organ Viability for Transplants

Researchers are adapting the wood frog’s ability to survive freezing to extend the viability of human organs for transplant. By mimicking the frog’s use of glucose as an antifreeze and controlled ice formation, scientists have significantly increased the storage time for livers and kidneys, potentially reducing the urgency of organ transplants and improving outcomes for patients on waiting lists.

via Space Daily|

#biotechnology #cryobiology #organ-preservation

healthtransplant-medicine2 years ago•0 min saved

"Gene-Edited Pig Liver Shows Promise in Human Transplant Experiment"

In a groundbreaking experiment at the Hospital of the University of Pennsylvania, a brain-dead patient was connected to a machine that circulated blood through a CRISPR-edited pig liver, demonstrating the potential for genetically engineered porcine organs to support the human circulatory system. The research, conducted by eGenesis, marks a significant advancement in transplant medicine and the use of CRISPR technology.

via STAT|

#crispr #egenesis #healthtransplant-medicine

medical-science2 years ago•9 min saved

Arkansas Man Receives Groundbreaking Eye and Face Transplant

A surgical team at NYU Langone Health in New York successfully performed the world's first whole-eye transplant in a living person, along with a partial face transplant, on Aaron James, a military veteran from Arkansas who suffered extensive facial injuries from an electric shock accident. Although Aaron cannot see out of the transplanted eye yet, his medical team is hopeful that vision may be restored in the future. The procedure, which involved transplanting the entire left eye and parts of the face from a single donor, marks a significant advancement in transplant medicine and could potentially benefit patients who have experienced eye loss due to trauma or cancer.

via CNN|

#eye-transplant #face-transplant #medical-breakthrough

health3 years ago•13 min saved

Revolutionary breakthrough: Rat organs successfully unfrozen and transplanted.

Researchers at the University of Minnesota have successfully transplanted vitrified and rewarmed rat kidneys, a breakthrough that could revolutionize transplant medicine. If the technique is successfully translated to humans, it could save tens of thousands of lives each year in the US alone. However, scaling up from rats to humans will require further scientific breakthroughs, and clinical trials are known to be challenging. Additionally, creating a nationwide network of cryopreserved organ banks will take time and raise ethical questions about who receives which kind of transplant.

via STAT|

#cryopreservation #health #medical-research