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Viral Reactivation

All articles tagged with #viral reactivation

Severe COVID may awaken dormant viruses, fueling long-COVID questions
health1 month ago

Severe COVID may awaken dormant viruses, fueling long-COVID questions

A study of 1,154 adults hospitalized with COVID-19 found that severe infection can reactivate dormant viruses in the body, including EBV, CMV, HSV and anelloviruses. Nearly half (about 550 participants) showed at least one reactivation, with different viruses turning on at different times and linking to immune/metabolic changes and persistent long-COVID symptoms in some patients. While these findings suggest a potential role for viral reactivation in disease severity and long COVID, the authors stress that RNA detection shows association, not causation, and call for prospective interventional trials to test whether antiviral treatment could improve outcomes.

via Live Science|
#anelloviruses#covid-19#ebv
Dormant viruses awaken during COVID-19, potentially driving severity and long COVID
health1 month ago

Dormant viruses awaken during COVID-19, potentially driving severity and long COVID

A study of 1,150 hospitalized COVID-19 patients found reactivation of dormant viruses from the Herpesviridae and Anelloviridae families in about 48% of cases, with HSV1 and CMV reactivating around day 20 and detection in nasal or blood samples linked to greater disease severity and higher 1-year mortality. Notably, Anelloviridae reactivation months after illness was associated with fatigue and disability (long COVID). The study shows association, not causation, and involved unvaccinated patients with early SARS-CoV-2 strains, so more research is needed to understand implications for prognosis and treatment."

via Medical News Today|
#anelloviridae#covid-19#health
Dormant viruses wake up in COVID-19 patients, impacting severity and long COVID
health1 month ago

Dormant viruses wake up in COVID-19 patients, impacting severity and long COVID

A year-long study of over 1,150 hospitalized, unvaccinated COVID-19 patients found that about 48% experienced reactivation of dormant viruses, notably Epstein-Barr virus and cytomegalovirus, with reactivations linked to greater acute severity and higher 1-year mortality in the critically ill; reactivation of Anelloviridae during recovery was associated with long COVID fatigue and disability. The study does not prove causation and has limitations (older SARS-CoV-2 strains, no vaccination status, sampling constraints), but suggests viral reactivation could influence COVID-19 outcomes and may inform risk assessment and future therapies pending further research.

via AOL.com|
#covid-19#cytomegalovirus#epstein-barr-virus
Severe COVID-19 May Wake Hidden Viruses, Study Shows
science1 month ago

Severe COVID-19 May Wake Hidden Viruses, Study Shows

A Nature study of 1,154 hospitalized COVID-19 patients across the U.S. and Canada found 11 dormant viruses reactivated within 40 days of admission, including herpes viruses (Epstein–Barr virus, cytomegalovirus) and Anelloviridae; reactivation appeared linked to inflammation and severe illness, with Anelloviridae reactivation associated with long‑term disability and long COVID, though causality is not proven. The findings may inform future diagnostics and treatments, but applicability to milder cases remains uncertain.

via Yahoo News UK|
#covid-19#epstein-barr-virus#herpes-viruses
Severe COVID-19 May Unleash Dormant Viruses, Study Finds
science1 month ago

Severe COVID-19 May Unleash Dormant Viruses, Study Finds

A multi-center study of 1,154 hospitalized COVID-19 patients over a year found reactivation of 11 dormant viruses within the first 40 days of admission, including Epstein-Barr virus, cytomegalovirus, herpes simplex virus-1, and Anelloviridae. Reactivation appeared linked to inflammation rather than immune suppression and was also associated with long-COVID and long-term disability in some cases, though causation was not established. The findings shed light on how severe COVID-19 can impact the body’s virome and may inform future diagnostics and treatments, especially for those with severe disease.

via Yahoo|
#anelloviridae#covid-19#cytomegalovirus
Dormant viruses reawaken in severe COVID, fueling long COVID and autoimmune risks
health2 months ago

Dormant viruses reawaken in severe COVID, fueling long COVID and autoimmune risks

Nature study of 1,154 hospitalized COVID-19 patients shows severe illness can reactivate dormant viruses (11 viruses detected within 40 days), notably Anelloviridae linked to long COVID, while EBV and CMV reactivation in nasal/blood samples correlate with higher mortality and complications; findings suggest viral reactivation monitoring could help prognosticate and treat acute and long COVID, though causality isn’t proven and more research is planned.

via CIDRAP|
#anelloviridae#autoimmune-disease#covid-19