Postmenopausal Ovaries Shift to Immune-Driven Role, Study Finds

New research shows that ovaries don’t simply stop after menopause; in mice, aging ovaries transition from reproductive function to an immune-dominant profile with increased immune cell activity, suggesting post-reproductive ovaries may influence aging and health. Human tissue data align with this immune shift, challenging the idea of inert postmenopausal ovaries and implying potential implications for healthcare and people who have had ovaries removed.