Tag

Ovaries

All articles tagged with #ovaries

science1 month ago•5 min saved

Ovaries Age Early, Reshaping Hormones and Immune Health Beyond Fertility

A Nature Aging study in mice shows ovaries begin aging well before menopause, with degraded coordination among eggs, follicles, and endocrine function, plus shifts toward inflammation and immune remodeling. This suggests reproductive aging is a progressive, tissue-level process—not just follicle depletion—and may continue after menopause, with implications for oophorectomy and broader women’s health; researchers are pursuing human tissue validation with Yale collaborators.

via ScienceAlert|

#aging #hormones #immune-system

health1 month ago•4 min saved

Menopause turns ovaries into immune-like hubs, study finds

A mouse study suggests that after menopause the ovaries don’t simply shut down; they take on an immune-like role, filling with immune cells and driving chronic low-grade inflammation (inflammaging) that could raise the risk of age-related diseases such as heart disease, Alzheimer's, arthritis and cancer.

via New York Post|

#aging #health #immunology

science1 month ago•4 min saved

Postmenopausal Ovaries Shift to Immune-Driven Role, Study Finds

New research shows that ovaries don’t simply stop after menopause; in mice, aging ovaries transition from reproductive function to an immune-dominant profile with increased immune cell activity, suggesting post-reproductive ovaries may influence aging and health. Human tissue data align with this immune shift, challenging the idea of inert postmenopausal ovaries and implying potential implications for healthcare and people who have had ovaries removed.

via ScienceAlert|

#aging #immune-system #menopause

science5 months ago•5 min saved

Older gut microbes unexpectedly rejuvenate ovaries in young mice

USC researchers found that fecal transplants from older mice into young, germ-free mice improved ovarian health and accelerated pup production, challenging the assumption that older microbiomes harm youth. The results suggest greater gut microbial diversity or altered estrogen signaling as potential mechanisms, but the exact reasons and relevance to humans remain unknown.

via ScienceAlert|

#aging #fertility #mice

health-and-science2 years ago•0 min saved

"The Enigmatic Potential of Ovaries in Extending Human Lifespan"

Ovaries hold the key to understanding human lifespan, according to recent research. Scientists are intrigued by the enigmatic role of ovaries in aging and longevity, with studies suggesting that they may play a crucial role in determining how long humans live. This new understanding could potentially lead to breakthroughs in extending human lifespan and improving overall health.

via Financial Times|

#health #health-and-science #human-lifespan

health2 years ago•2 min saved

Unveiling a Novel Culprit Behind Female Infertility

Scientists from Tsinghua University in China have identified a new genetic change, Eif4enif1, as a key cause of female infertility. This genetic change affects the functioning of egg cells and prevents the ovaries from releasing eggs regularly, making conception almost impossible. The researchers found that the harmful DNA pattern affects the mitochondria within the egg cells, which are responsible for converting fuel to energy. The discovery could lead to potential gene-editing drugs that address the issue and offer effective treatment for infertility.

via Daily Mail|

#egg-cells #female-infertility #genetic-change

health3 years ago•10 min saved

Ovaries Hold Clues to Aging Secrets

The ovaries age faster than any other organ in the body, and researchers are studying how to slow down that process to have health benefits for women and men. The loss of hormones during menopause sets off a cascade of negative health effects, and women live longer than men on average but spend more of their older years in poor health. Researchers are trying to understand why the ovaries seem intricately connected to health and longevity, and unraveling these mysteries could mean extending a person’s reproductive years and potentially lifespan by delaying menopause. Studies like these could yield insights on a much shorter timescale than those done on other tissues in the body, which could have implications for aging in both women and men.

via WIRED|

#aging #health #menopause

health3 years ago•5 min saved

Can Rapamycin Extend Fertility? Doctors Investigate.

Researchers at Columbia University are conducting a human study to determine whether the drug rapamycin can slow down aging in ovaries. The study aims to help reduce the pains of menopause and extend the lives of people of all genders with a cheap, once-weekly drug that's already widely used by some cancer patients and transplant recipients. The drug rapamycin could help "conserve those limited, precious eggs" and keep the ovaries functioning more like young, healthy ones do.

via Insider|

#aging #fertility #health

health3 years ago•3 min saved

"Researcher advocates for the end of menopause"

Piraye Yurttas Beim, CEO of Celmatix, a women’s health-focused biotech company, is calling for an end to menopause and the development of a drug to extend ovarian function. She argues that the ovary is important for metabolic function, immune function, and brain health, and that women's health has historically been underfunded. Beim and her team are starting from scratch to develop a drug that will help ovarian function decline slowly, the way testicular function declines for men.

via msnNOW|

#biotech #health #menopause

health3 years ago•2 min saved

The Case for Ending Menopause: A Top Researcher's Perspective.

Piraye Yurttas Beim, CEO of Celmatix, a women’s health-focused biotech company, is calling for an end to menopause. She believes that the ovaries are the central command of a woman’s health and vitality and that they are important for metabolic function, immune function, and brain health. Beim founded Celmatix to find a drug to extend ovarian function and end menopause. She believes that menopause is a catastrophic public health crisis and life event, and there is a huge disparity in funding for research and innovation in this space. Beim and her team are working on a drug to help extend ovarian function and help it decline slowly, the way that testicular function declines for men.

via SheKnows|

#health #innovation #menopause

health3 years ago•3 min saved

"Researcher advocates for the end of menopause"

Piraye Yurttas Beim, CEO of Celmatix, a women’s health-focused biotech company, is calling for an end to menopause and the extension of ovarian function. She argues that the ovary is important for metabolic function, immune function, and brain health, and that women's health has historically been underfunded and overlooked. Dr. Yurttas Beim and her team are working on a drug to extend ovarian function and help it decline slowly, similar to testicular function in men. She believes that women should not simply accept menopause as a natural process and that women's health deserves more attention and funding.

via Yahoo Life|

#health #menopause #ovaries