
The Immune Drama Behind Seasonal Allergies
Seasonal allergies happen when pollen is misread as a threat by the immune system. Dendritic cells help sensitization, antibodies cluster on mast cells, and subsequent pollen exposure releases histamine and other chemicals that inflame the eyes, nose, and airways, causing itching, congestion, and a runny nose. Eosinophils can prolong symptoms, and about a quarter of US adults are affected, sometimes after one exposure or across several seasons. Treatments like antihistamines and nasal steroids dampen the inflammatory response, while saline rinses help flush out irritants. Different seasons bring different pollen, but effective management is possible with medication and avoidance strategies.













