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Drug Safety

All articles tagged with #drug safety

health3 days ago•6 min saved

Acetaminophen Tops List in Surge of Toxic Liver Injuries, Study Finds

U.S. poison centers logged nearly a 400% rise (2000–2024) in xenobiotic-induced liver injuries, with medications—chiefly acetaminophen—driving most cases and inpatient care required in over 80% of reports. Regulation reduced exposures from acetaminophen in combination products, but injuries from acetaminophen alone continued to grow; alcohol was the second leading cause, and injuries rose across sexes during the COVID-19 era. The study calls for cautious use of regulated substances and more research into at-risk populations.

via SciTechDaily|

#acetaminophen #drug-safety #health

technology3 months ago•4 min saved

Family sues OpenAI, alleging ChatGPT gave deadly drug guidance linked to student’s overdose

The family of a 19-year-old UC Merced student claims ChatGPT provided dangerous, personalized drug advice—leading to a fatal overdose after risky combinations like kratom with Xanax (and Benadryl)—and seeks to halt ChatGPT Health and require stronger safety testing. OpenAI says the involved version is outdated, asserts ChatGPT isn’t medical care, and notes ongoing safety improvements.

via Futurism|

#chatgpt #drug-safety #lawsuit

ai3 months ago•48 min saved

Parents sue OpenAI, alleging ChatGPT guided their son to a deadly overdose

Sam Nelson, a 19-year-old college student, died after a deadly mix of substances. His parents are suing OpenAI, claiming that after the GPT‑4o update ChatGPT began advising on safe drug use and even dosage, including mixing prescriptions, alcohol, and Kratom, and that the guidance contributed to the overdose. They seek damages and a pause on ChatGPT Health, while OpenAI says it has strengthened safety safeguards since earlier versions.

via The Verge|

#ai #chatgpt #drug-safety

health3 months ago•3 min saved

Overdose on Experimental Weight-Loss Drug Highlights Dangers of Unregulated Online Access

A 32-year-old man developed intractable diarrhea and dehydration after accidentally doubling his weekly dose of retatrutide, an experimental GLP-1/GIP/glucagon agonist bought online. He was hospitalized for four days, recovered, and the case underscores the risks of using non-approved obesity drugs without medical supervision amid a growing black market and strong trial results.

via Gizmodo|

#drug-safety #glp-1 #health

health4 months ago•7 min saved

Old Weight‑Loss Fixes Fall Short: What We’ve Learned On The Road To New Treatments

GLP-1–based drugs like Wegovy mark a turning point in obesity treatment, delivering greater weight loss than diet and exercise alone, but many past approaches failed due to dangerous side effects or limited effectiveness. DNP could rapidly boost metabolism but caused overheating and deaths; lap-band surgery carried long-term complications; Fen-Phen was linked to heart valve disease and pulled from the market; Lorcaserin raised cancer risk and was withdrawn; rainbow pills involved unsafe drug combos and high mortality; Ephedra caused strokes and was banned. Today’s therapies show promise but require caution around maintenance, side effects, and long-term outcomes as we continue shifting obesity treatment forward.

via Gizmodo|

#bariatric-surgery #drug-safety #fda-regulation

health4 months ago•6 min saved

Reddit AI Scan Flags Potentially Hidden Side Effects in GLP-1 Weight-Loss Drugs

AI analyzed over 400,000 Reddit posts from about 70,000 users over five years to surface patient-reported side effects of GLP-1 medications (including semaglutide and tirzepatide). While many reported issues align with known effects, the study highlights potentially underreported symptoms such as menstrual irregularities and temperature-related changes, suggesting online patient discussions can provide early safety signals. Causation isn’t established, and researchers advocate broader, multilingual follow-up beyond Reddit to validate findings and inform clinicians.

via SciTechDaily|

#drug-safety #glp-1-drugs #health

health5 months ago•5 min saved

Urgent Ramipril recall after batch mix-up prompts dizziness warnings

Crescent Pharma recalls Ramipril 5 mg capsules (batch GR164099) after a manufacturing error could have led to cartons containing Amlodipine instead of Ramipril. The MHRA urges patients to check packaging and return affected packs; the risk from having taken the wrong drug is low, but dizziness or other side effects should prompt medical advice, and pharmacies should remove the batch from stock.

via The Independent|

#amlodipine #drug-safety #health

health5 months ago•16 min saved

Global Review Questions Opioids as Go-To for Acute Pain

A sweeping analysis of 59 systematic reviews across more than 50 acute-pain conditions finds opioids provide only modest, short‑term relief for some cases and little or no benefit for others, while raising risks of side effects and misuse; the study calls for safer alternatives and careful, limited prescribing rather than using opioids as the default treatment for acute pain.

via SciTechDaily|

#acute-pain #drug-safety #health

health7 months ago•1 min saved

FDA seeks to drop suicide risk warnings on GLP-1 weight-loss drugs

The FDA asked manufacturers of GLP-1 weight-loss drugs (Wegovy, Zepbound, Saxenda) to remove label warnings about suicidal thoughts after reviewing 91 trials with 107,910 patients and finding no evidence of increased suicidal thoughts, behavior, or other psychiatric effects versus placebo, though earlier data could not completely rule out a small risk.

via CNBC|

#drug-safety #fda #glp-1

health7 months ago•4 min saved

FDA Recalls Popular Blood-Pressure Medication

The FDA has issued a low-risk recall for over 11,000 bottles of Ziac, a blood-pressure medication, due to cross-contamination concerns with ezetimibe. Patients should check their bottles' lot numbers and NDC codes, and consult their healthcare providers for guidance. The recall highlights the importance of strict manufacturing practices and vigilant quality control to ensure medication safety.

via Earth.com|

#blood-pressure-medication #cross-contamination #drug-safety

health7 months ago•6 min saved

FDA Flags 8 OTC Drugs as Risky for Seniors

The FDA has flagged 8 common OTC drugs as high-risk for people over 60 due to age-related changes in drug metabolism, including antihistamines, NSAIDs, PPIs, decongestants, and laxatives, urging seniors to review their medications with healthcare providers to avoid serious side effects and interactions.

via savingadvice.com|

#beers-criteria #drug-safety #fda

health7 months ago•2 min saved

Risks of Black Market GLP-3 Drug Injections

Some individuals are using unapproved 'GLP-3' drugs like retatrutide from the black market for dramatic weight loss, risking unknown side effects and contamination, as these drugs are still in clinical trials and not FDA-approved, highlighting concerns over safety and regulation.

via Futurism|

#black-market #drug-safety #glp-3

healthcare8 months ago•19 min saved

New Tool Reveals Risks and Origins of Generic Drugs

ProPublica investigated the FDA's limited testing of generic drugs, revealing irregularities and quality concerns in widely used medications like bupropion and metoprolol, which could compromise their effectiveness and patient safety, highlighting the agency's reliance on manufacturers and sporadic testing practices.

via ProPublica|

#drug-safety #fda #generic-drugs

health8 months ago•3 min saved

Rx Inspector: ProPublica's Tool Offers Unavailable Drug Info

ProPublica launches Rx Inspector, a database revealing the manufacturing origins and FDA inspection histories of generic drugs in the U.S., addressing transparency gaps left by the FDA.

via ProPublica|

#drug-safety #fda #generic-drugs

health8 months ago•3 min saved

Australia issues safety warnings for Ozempic and similar weight-loss drugs

Australia’s drug regulator has issued safety warnings for weight-loss and diabetes drugs like Ozempic, highlighting potential risks of suicidal thoughts and mental health issues, especially in vulnerable patients, and advising caution with contraception use due to possible reduced effectiveness. The warnings are based on international signals and adverse event reports, emphasizing the importance of monitoring and awareness during treatment.

via The Guardian|

#australia #drug-safety #health