Tag

Epigenetic Clock

All articles tagged with #epigenetic clock

health14 days ago•8 min saved

Hidden Onset: Barrett's Esophagus Likely Begins in Early Adulthood

Researchers using an esophagus-specific epigenetic clock analyzed UK cohorts and estimate that Barrett's esophagus often begins in early adulthood (roughly ages 20–30), decades before clinical diagnosis, creating a long premalignant window that may accumulate cancer-driving mutations and suggesting a shift toward personalized, continuous-risk screening rather than strict age cutoffs; however, broad screening of all GERD patients could lead to oversurveillance.

via Medscape|

#barretts-esophagus #epigenetic-clock #esophageal-adenocarcinoma

science3 months ago•33 min saved

Youth trauma accelerates aging clock and shifts gaze away from eyes

A study of 36 maltreated children and 60 controls finds that childhood abuse is associated with accelerated epigenetic aging and with reduced looking at eyes during social videos; the two changes occur in parallel and both relate to higher behavioral difficulties, but the cross‑sectional design cannot establish causality and there are sample limitations.

via PsyPost|

#accelerated-aging #childhood-trauma #epigenetic-clock

health4 months ago•4 min saved

Plant-Forward Diet Linked to Slower Biological Aging

A large U.S. study of roughly 5,000 people found that diets centered on plant-based foods (fruits, vegetables, whole grains, nuts, beans) and lower in animal products are linked to slower aging at the genetic level, as measured by the epigenetic clock. However, the benefit depends on diet quality—plant-based does not help if it’s high in refined grains, sugar, and ultra-processed foods. The anti-aging effect likely comes from more fiber and antioxidants and less inflammation, with implications that the pace of your biological clock can signal lifespan beyond your actual age.

via VICE|

#aging #antioxidants #epigenetic-clock

science6 months ago•6 min saved

Blood Theobromine Tied to Slower Biological Aging in European Cohorts

A large observational study across two European cohorts (TwinsUK and KORA) finds higher blood theobromine, a compound found in dark chocolate, cocoa, and coffee, is associated with slower biological aging—lower epigenetic age acceleration and longer telomeres—even after adjusting for caffeine and other factors. While the associations are strong, causality isn’t established, and researchers urge controlled trials before making dietary recommendations; the link was particularly notable in former smokers.

via Indian Defence Review|

#aging #chocolate #epigenetic-clock

science9 months ago•3 min saved

Australian Ecology Researcher Loses Two Papers

A molecular ecology researcher, formerly at CSIRO, lost two papers and received an expression of concern for a third due to data issues related to DNA methylation-based epigenetic clocks used to estimate animal ages, leading to retractions and ongoing investigations.

via Retraction Watch|

#animal-aging #dna-methylation #epigenetic-clock

health11 months ago•3 min saved

Strong Social Bonds May Slow Biological Aging

A study shows that strong, sustained social connections throughout life can slow biological aging by reducing inflammation and resetting epigenetic clocks, highlighting the importance of social support for health and longevity.

via SciTechDaily|

#aging #epigenetic-clock #health

science1 year ago•2 min saved

Amphibian that Stops Aging: A Breakthrough in Longevity

The axolotl, an amphibian capable of regenerating tissues and resisting cancer, shows signs of negligible aging at the molecular level, with DNA methylation patterns remaining stable after the first four years of life, suggesting it may experience little to no biological aging beyond early development.

via Ynetnews|

#aging #axolotl #dna-methylation

health3 years ago•3 min saved

"Scientifically Reduce Your Body's Age with These 4 Methods"

Leading longevity expert Steve Horvath advises against spending money on expensive biological age tests and instead suggests four simple and affordable actions to reduce biological age: not smoking, increasing vegetable intake, exercising, and reducing chronic inflammation. Horvath's research on epigenetic clocks has shown that these lifestyle changes can measurably lower biological age. He emphasizes that while DNA-based tests are available, they are not clinically meaningful yet, and individuals should focus on known evidence-based strategies for healthy aging.

via Business Insider India|

#aging #biological-age #epigenetic-clock