All articles tagged with #gray matter
A study of 2,044 older adults in Japan found that lower plasma vitamin C levels are associated with reduced gray matter volume and weaker connectivity in the brain's default mode network, suggesting nutrition may support healthy brain aging, though the study is observational and does not prove causation.
In a Japanese study of about 2,000 older adults, higher blood plasma vitamin C levels were linked to better-preserved brain gray matter and stronger connectivity in the default mode network, even after adjusting for age, smoking, diabetes and other factors. While the finding suggests vitamin C status may play a role in brain health, the study is observational and cannot prove causation, with limitations including a single blood measurement and limited generalizability beyond older Japanese adults. The results highlight dietary vitamin C sources rather than supplements as a potential piece of the broader brain-health puzzle.
A study of about 2,000 adults over 64 found that lower blood plasma vitamin C is associated with reduced gray matter volume and weaker connectivity in the brain's default mode network, suggesting vitamin C status may relate to brain aging, though the results are observational and longitudinal research is planned to explore causality and cognitive impacts.
A longitudinal MRI study of 25 first-time fathers shows early widespread gray matter reductions in areas tied to sensory processing, self-referential thinking, and social cognition during the first six weeks after birth, followed by later increases in frontal and cerebellar regions related to planning and emotional control. Functional connectivity also shifts, weakening links to sensory regions and strengthening those related to emotion and cognitive control. Researchers identify weeks six to nine as a critical window for paternal neuroplasticity, indicating that the brain’s reorganization is a real biological feature of early fatherhood, not just a social adjustment.
A small MRI study followed 25 new fathers across 24 weeks after birth, revealing rapid brain changes—early widespread gray matter reductions in multiple regions, later region-specific growth and altered connectivity—indicating paternal neuroplasticity, though generalizability is limited by the single-site, non-diverse sample and lack of pre-birth baseline.
A small study of 25 fathers scanned up to 24 weeks after birth finds rapid, dynamic brain restructuring: initial widespread gray-matter reductions followed by regional swelling, particularly in areas tied to attention, reward, and emotional processing, suggesting a 'parental brain network' tailored for caregiving. Changes resemble some maternal brain shifts but are preliminary, with unclear longevity and potential variation between first and later children.
A study of 1,647 adults over about 12 years found that closer adherence to the MIND diet (Mediterranean–DASH Diet) is linked to slower brain aging: every 3-point increase in the diet score corresponded to 20% less gray-matter loss (roughly 2.5 years of delay) and 8% less ventricular enlargement (about 1 year). Berries and poultry were key contributors; sweets and fried foods worsened hippocampal health. Unexpectedly, higher whole-grain intake was linked to faster decline, while higher cheese intake was associated with slower gray-matter and hippocampal loss and less ventricular enlargement—a notable exception to the diet’s usual limits. Benefits were stronger among older individuals, those who were physically active, and those not overweight, suggesting diet works with other healthy habits to protect brain structure.
A long-term study of over 1,600 middle-aged and older adults found that stronger adherence to the MIND diet slowed brain aging, with about 2.5 years of reduced aging and 8%–8.8% less ventricular expansion over roughly 12 years; specific foods like berries and poultry were associated with protective brain changes, while sweets and fried foods linked to worse outcomes. The study notes limitations such as demographic homogeneity and lack of APOE data, but suggests the MIND diet could be an accessible strategy to support brain health as populations age.
A study using structural MRI and machine learning identifies two distinct physical subtypes of ADHD. Subtype 1 shows increased gray matter in the frontal regions and cerebellum, linked to severe inattention; Subtype 2 shows widespread gray matter reductions in the cerebellum, frontal regions, and hippocampus, tied to higher overall severity and hyperactive/impulsive symptoms. Through a pseudo-time-series analysis and causal-network mapping, researchers reveal subtype-specific brain–behavior progression patterns, suggesting potential for personalized diagnosis and treatment, though longitudinal studies are needed to confirm progression and acknowledge cross-sectional design limitations.
A Dutch-led study comparing brain scans before/after second pregnancies with first-time and never-pregnant women found that a second pregnancy induces distinctive brain changes—especially in networks processing sensory input and attention—and shows gray-matter reductions likely due to neuroplasticity, not degeneration; while some adaptations mirror the first pregnancy, the second brings additional refinements to support raising two children, with potential links to bonding and maternal mental health.
A study found that wearing rose scent oil for a month can increase gray matter volume in specific brain regions, particularly the posterior cingulate cortex, which is linked to memory and association. This suggests that certain scents might influence brain structure and could have potential in preventing neurodegenerative conditions like dementia, although more research is needed.
A study demonstrates that cognitive behavioral therapy (CBT) can lead to structural changes in the brain, specifically increasing gray matter volume in areas associated with emotion processing, such as the amygdala and hippocampus, in patients with depression.
Higher prenatal exposure to certain phthalates, commonly found in commercial products, has been linked to reduced gray matter in children's brains by age 10 and decreased IQ levels at age 14. The study found that alterations in gray matter volumes partially explain the connection between phthalate exposure and lower IQ. Additionally, prenatal exposure was associated with decreased white matter volumes in female children. The widespread exposure to phthalates and lax regulations raise significant public health concerns.
A study published in Neuroimage: Reports found that music lessons can increase gray matter in several brain regions of older adults, regardless of the type of music lesson. The research suggests that music learning could be a non-pharmacological treatment for age-related cognitive decline. The study involved 132 participants who underwent MRI scans and cognitive assessments before and after six months of music lessons. Both the music intervention group and the control group showed an increase in cerebellar gray matter volume. The group taking piano lessons also demonstrated improved tonal working memory. The study highlights the potential of music interventions as a non-pharmacological approach to improve cognitive function in older adults.
Heavy drinking during adolescence can lead to thinner cortical gray matter and altered neurotransmission in adulthood, according to a recent study. The research, which utilized MRI and TMS-EEG technology, found that young adults with a history of heavy drinking exhibited lower gray matter thickness and increased N45 potential, indicative of inhibitory GABA and excitatory glutamate neurotransmitter activity. The study highlights the long-term, detrimental impact of adolescent heavy drinking on adult brain structure and function, particularly in the frontal and parietal lobes.