Tag

Heart Failure

All articles tagged with #heart failure

health11 days ago•7 min saved

King's College Study Links Pomegranate Metabolite to 80% Improvement in Heart Failure Models

Researchers at King's College London have identified urolithin A, a compound produced in the body after consuming pomegranates, walnuts, and certain berries, as a potential treatment for heart failure with preserved ejection fraction (HFpEF). Published in Science Advances, the study shows that urolithin A activates the PKGIα protein, improving heart relaxation by up to 80% in animal models and engineered human heart tissue. This condition, which affects nearly half a million people in the UK, involves a stiff heart that cannot fill properly between beats, leading to fatigue and breathlessness. While current treatments are limited due to the complex nature of HFpEF, this new mechanism offers a promising therapeutic target. However, experts caution that these results are preliminary, as they are based on experimental models rather than human clinical trials. Although urolithin A has a favorable safety profile in previous human studies, further research is required to confirm its efficacy as a treatment for patients.

via sciencedaily.com|

#cardiovascular-health #clinical-trials #health

entertainment21 days ago•20 min saved

Duncan Sheik’s Final Public Moment Before Tragic Passing at 56

Duncan Sheik, the Grammy-winning singer‑songwriter behind Barely Breathing, appeared happy and energetic on the Olivier Awards red carpet in London in April 2026 — his final public outing — before his death at 56. After being hospitalized in critical but stable condition, his family asked for privacy, and it was later confirmed he had died; People reported the cause as heart failure leading to cardiac arrest. Sheik also earned a Grammy for Spring Awakening on Broadway.

via Page Six|

#barely-breathing #death #duncan-sheik

science1 month ago•5 min saved

Urolithin A from Pomegranates Boosts Heart Relaxation in Lab HFpEF Models

Lab studies from King’s College London show that urolithin A, a compound produced after eating pomegranates, activates PKGIα to improve heart relaxation, reduce scar tissue, and limit heart-muscle enlargement in models of heart failure with preserved ejection fraction, with functional gains up to 80%. While promising, findings are in animals and engineered human tissue; human trials are needed and dietary strategies to raise urolithin A levels are being explored, not yet a proven treatment.

via SciTechDaily|

#heart-failure #hfpef #pkgia

health1 month ago•5 min saved

Shingles vaccine may curb heart-disease risk, large real-world study finds

A large real-world analysis of over 70,000 people found that the Shingrix shingles vaccine was associated with better cardiovascular outcomes than the older Zostavax, including about 9% more time free of cardiovascular disease over seven years and 10% lower risk of heart disease, 12% lower risk of heart failure, and a 12% lower risk of stroke in men; while the results are robust, the study cannot prove causation and more research is needed to confirm a true protective effect.

via Nature|

#cardiovascular-disease #health #heart-failure

technology1 month ago•3 min saved

Blink-Eye AI Reads ECGs to Flag Heart Disease in Seconds

A team has built a “superhuman” AI that analyzes routine ECGs to detect signs of heart failure and heart valve disease within seconds. In a US trial of 67,000 patients, the AI identified up to 81% of heart-failure cases and 90% of valve-disease cases. While not a standalone diagnosis, the tool flags high-risk patients for rapid echocardiograms to speed up diagnosis and treatment, potentially cutting wait times for essential imaging and improving outcomes.

via The Guardian|

#ai #ecg #echocardiogram

health-and-medicine1 month ago•10 min saved

Chronic Melatonin Use Linked to Elevated Heart Failure Risk

A large, observational study using de-identified health records found that adults with chronic insomnia who used melatonin for at least 12 months had about a 90% higher five-year risk of developing heart failure (4.6% vs 2.7%), plus higher rates of heart-failure-related hospitalization (19.0% vs 6.6%) and all-cause death (7.8% vs 4.3%). The results do not prove causation and could be influenced by unmeasured factors or misclassification of OTC melatonin use; researchers call for more research and cautious discussion of long-term melatonin use with patients.

via Science Daily|

#cardiovascular-risk #health-and-medicine #heart-failure

health1 month ago•7 min saved

Global Guidelines Redefine Heart Failure to Detect Hidden Cases

Experts from the AHA, World Heart Federation, ACC, and ESC propose a revised universal definition of heart failure that recognizes the condition can exist even with a normal ejection fraction, moving beyond EF as the sole diagnostic measure. The framework emphasizes imaging, blood work, and genetics, and adds 18 potential causes to unify classifications worldwide. They note EF cutoffs were arbitrary and that heart failure can evolve over time, with future guidelines to follow; approximately 55 million people are affected globally.

via ScienceAlert|

#circulation #consensus #ejection-fraction

science1 month ago•36 min saved

iPSC-derived stem cells show strong heart-function gains in a Chinese trial

In a small Chinese study, 10 patients with severe heart failure received injections of their own induced pluripotent stem cells differentiated into heart muscle cells. Over 12 months, 9 of the 10 showed significant improvements in cardiac function and six-minute walk distance compared with a control group that underwent bypass surgery; one control patient died eight months after surgery. Some patients experienced temporary tachycardia, but no severe adverse events were reported. Researchers say longer, larger trials are needed to assess long-term safety and benefit.

via Yahoo News Canada|

#cardiac-regeneration #clinical-trial #heart-failure

entertainment1 month ago•17 min saved

Five Heartbeats Star Michael Wright Dies at 70

Michael Wright, best known for playing Eddie King Jr. in The Five Heartbeats, died at 70 in Los Angeles from heart failure and complications related to Marchiafava-Bignami, a rare degenerative neurological disease. The New York City native built a decades-long career in film and television since the late 1970s, with credits including The Wanderers, Streamers, Sugar Hill and appearances on TV staples like V, Oz, Miami Vice, and New York Undercover. He is survived by his wife Susan Wright, as well as his daughter and stepchildren.

via Page Six|

#eddie-king-jr #entertainment #heart-failure

health1 month ago•47 min saved

Stem-cell therapy shows promising heart recovery in a small Chinese trial

In a small 12‑month trial at Nanjing Drum Tower Hospital, 10 heart‑failure patients received stem cells derived from their own iPSCs and differentiated into heart muscle cells injected into diseased heart tissue, while 10 controls underwent bypass surgery. Nine treated patients showed significant heart‑function improvements at 12 months versus the control group, with better six‑minute walk test results and an increased ejection fraction on average. No severe adverse events were reported in the treated group, though two patients experienced tachycardia that resolved. One control patient died eight months after surgery. While promising, the study’s tiny size means larger trials are needed to confirm safety and benefit.

via Yahoo|

#cardiac-function #clinical-trial #health

science2 months ago•36 min saved

Gas-station Kratom Gummies Trigger Lifesaving Heart Care for 27-Year-Old Mom

Amanda Goodsell, 27, suffered a severe reaction to kratom capsules bought at a gas station for persistent leg pain, which led to heart failure and two cardiac arrests. She required life support and was initially told she might need a heart transplant, but gradually stabilized and now will need a defibrillator and lifelong heart medications. The FDA warns kratom is not FDA-approved for medical treatment and continues to monitor safety data.

via Yahoo News Canada|

#defibrillator #fda #heart-failure

health2 months ago•6 min saved

Five Subtle Signs That May Signal Early Heart Failure

A US cardiologist highlights five easy-to-miss signs of heart failure—rapid overnight weight gain, a persistent cough, sudden fullness with reduced appetite, unexplained brain fog, and waking at night gasping for air—emphasizing that spotting these subtle clues early can prompt evaluation and improve outcomes for those at risk.

via The Times of India|

#cardiology #fluid-retention #health

entertainment3 months ago•5 min saved

Harvey Weinstein Hospitalized in NYC After Heart Failure

Harvey Weinstein, 74, is recuperating at Bellevue Hospital in New York after reportedly suffering heart failure tied to pneumonia. His publicist confirmed he is resting and receiving treatment, with doctors monitoring his heart and administering antibiotics; officials expect a hospital stay of several weeks as his ongoing legal proceedings continue elsewhere.

via Los Angeles Times|

#bellevue-hospital #entertainment #harvey-weinstein

health3 months ago•22 min saved

Amgen recalls nearly 1M heart and kidney meds over tablet contamination

Nearly 1 million bottles (about 944,142) of Amgen medications Corlanor (ivabradine) and Sensipar (cinacalcet) have been recalled nationwide after foreign matter was found on the exterior surface of tablets in a reserve sample. The issue was localized to the coating and occurred in bottles packaged in AML Building 23; the recalls cover multiple dosages and bottle counts distributed from Oct 28, 2021 to Dec 30, 2025. The FDA classified the recall as Class II with low overall patient-safety risk, and there have been no reported complaints.

via New York Post|

#cinacalcet #fda #health

health3 months ago•27 min saved

COVID-19 may raise lifetime risk of dangerous pulmonary hypertension

A new Scientific Reports study links COVID-19 infection to an increased risk of developing pulmonary hypertension (PH), and finds that people who later develop post‑COVID obstructive sleep apnea are more likely to experience heart failure and PH. The article explains PH as a progressive, potentially fatal high blood pressure in the lung arteries, outlines its symptoms and stages, how it’s diagnosed, and available treatments (including various medications and lifestyle changes), and notes risk factors such as age, smoking, congenital heart defects, and high altitude.

via New York Post|

#cardiovascular-disease #covid-19 #health