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Heart Failure

All articles tagged with #heart failure

Global Guidelines Redefine Heart Failure to Detect Hidden Cases
health1 day ago

Global Guidelines Redefine Heart Failure to Detect Hidden Cases

Experts from the AHA, World Heart Federation, ACC, and ESC propose a revised universal definition of heart failure that recognizes the condition can exist even with a normal ejection fraction, moving beyond EF as the sole diagnostic measure. The framework emphasizes imaging, blood work, and genetics, and adds 18 potential causes to unify classifications worldwide. They note EF cutoffs were arbitrary and that heart failure can evolve over time, with future guidelines to follow; approximately 55 million people are affected globally.

iPSC-derived stem cells show strong heart-function gains in a Chinese trial
science2 days ago

iPSC-derived stem cells show strong heart-function gains in a Chinese trial

In a small Chinese study, 10 patients with severe heart failure received injections of their own induced pluripotent stem cells differentiated into heart muscle cells. Over 12 months, 9 of the 10 showed significant improvements in cardiac function and six-minute walk distance compared with a control group that underwent bypass surgery; one control patient died eight months after surgery. Some patients experienced temporary tachycardia, but no severe adverse events were reported. Researchers say longer, larger trials are needed to assess long-term safety and benefit.

Five Heartbeats Star Michael Wright Dies at 70
entertainment3 days ago

Five Heartbeats Star Michael Wright Dies at 70

Michael Wright, best known for playing Eddie King Jr. in The Five Heartbeats, died at 70 in Los Angeles from heart failure and complications related to Marchiafava-Bignami, a rare degenerative neurological disease. The New York City native built a decades-long career in film and television since the late 1970s, with credits including The Wanderers, Streamers, Sugar Hill and appearances on TV staples like V, Oz, Miami Vice, and New York Undercover. He is survived by his wife Susan Wright, as well as his daughter and stepchildren.

Stem-cell therapy shows promising heart recovery in a small Chinese trial
health4 days ago

Stem-cell therapy shows promising heart recovery in a small Chinese trial

In a small 12‑month trial at Nanjing Drum Tower Hospital, 10 heart‑failure patients received stem cells derived from their own iPSCs and differentiated into heart muscle cells injected into diseased heart tissue, while 10 controls underwent bypass surgery. Nine treated patients showed significant heart‑function improvements at 12 months versus the control group, with better six‑minute walk test results and an increased ejection fraction on average. No severe adverse events were reported in the treated group, though two patients experienced tachycardia that resolved. One control patient died eight months after surgery. While promising, the study’s tiny size means larger trials are needed to confirm safety and benefit.

Gas-station Kratom Gummies Trigger Lifesaving Heart Care for 27-Year-Old Mom
science1 month ago

Gas-station Kratom Gummies Trigger Lifesaving Heart Care for 27-Year-Old Mom

Amanda Goodsell, 27, suffered a severe reaction to kratom capsules bought at a gas station for persistent leg pain, which led to heart failure and two cardiac arrests. She required life support and was initially told she might need a heart transplant, but gradually stabilized and now will need a defibrillator and lifelong heart medications. The FDA warns kratom is not FDA-approved for medical treatment and continues to monitor safety data.

Harvey Weinstein Hospitalized in NYC After Heart Failure
entertainment1 month ago

Harvey Weinstein Hospitalized in NYC After Heart Failure

Harvey Weinstein, 74, is recuperating at Bellevue Hospital in New York after reportedly suffering heart failure tied to pneumonia. His publicist confirmed he is resting and receiving treatment, with doctors monitoring his heart and administering antibiotics; officials expect a hospital stay of several weeks as his ongoing legal proceedings continue elsewhere.

Amgen recalls nearly 1M heart and kidney meds over tablet contamination
health1 month ago

Amgen recalls nearly 1M heart and kidney meds over tablet contamination

Nearly 1 million bottles (about 944,142) of Amgen medications Corlanor (ivabradine) and Sensipar (cinacalcet) have been recalled nationwide after foreign matter was found on the exterior surface of tablets in a reserve sample. The issue was localized to the coating and occurred in bottles packaged in AML Building 23; the recalls cover multiple dosages and bottle counts distributed from Oct 28, 2021 to Dec 30, 2025. The FDA classified the recall as Class II with low overall patient-safety risk, and there have been no reported complaints.

COVID-19 may raise lifetime risk of dangerous pulmonary hypertension
health2 months ago

COVID-19 may raise lifetime risk of dangerous pulmonary hypertension

A new Scientific Reports study links COVID-19 infection to an increased risk of developing pulmonary hypertension (PH), and finds that people who later develop post‑COVID obstructive sleep apnea are more likely to experience heart failure and PH. The article explains PH as a progressive, potentially fatal high blood pressure in the lung arteries, outlines its symptoms and stages, how it’s diagnosed, and available treatments (including various medications and lifestyle changes), and notes risk factors such as age, smoking, congenital heart defects, and high altitude.

Long-Term Melatonin Use Linked to Higher Heart Failure Risk, Preliminary Findings
science2 months ago

Long-Term Melatonin Use Linked to Higher Heart Failure Risk, Preliminary Findings

A large, multi-country analysis of about 130,000 adults found that long-term melatonin prescriptions (>1 year) were associated with an 89% higher risk of heart failure and roughly double the odds of death over five years versus those not prescribed melatonin. The study is preliminary, not peer‑reviewed, and relies on prescription records to infer melatonin use—OTC use in the control group could bias results. While melatonin is commonly used and generally safe short‑term, these findings underscore the need for prospective trials to clarify safety and guidance for long-term use.

A 23-Year-Old’s Breathless Misdiagnosis Reveals Hidden End-Stage Heart Failure
health2 months ago

A 23-Year-Old’s Breathless Misdiagnosis Reveals Hidden End-Stage Heart Failure

Jenny Milne was misdiagnosed with gallbladder issues when she actually had end-stage heart failure from restrictive cardiomyopathy; after a 24-hour heart monitor, she was diagnosed in early 2021 and underwent mitral valve replacement in 2022, putting her heart failure into remission. Now 29, she advocates for early detection and awareness that heart disease can affect people of any age, working with HeartLife Foundation to raise public and medical professional awareness in Canada.

Cheap Digoxin May Cut Hospitalizations in Heart Failure Patients
health3 months ago

Cheap Digoxin May Cut Hospitalizations in Heart Failure Patients

UMCG-led studies suggest adding a low-dose digoxin to standard heart failure therapy reduces cardiovascular death risk and HF-related hospitalizations. A broader meta-analysis found a significant ~25% reduction in HF admissions, supporting digoxin’s safety and cost-effectiveness at under ten cents per day. If confirmed, these findings could influence guidelines and broaden access to this inexpensive, centuries-old treatment.

Emergency Heart Pump Saves Mom After Near-Fatal Labor Scare
health4 months ago

Emergency Heart Pump Saves Mom After Near-Fatal Labor Scare

Casey Gould faced a life-threatening heart condition discovered during labor when her ejection fraction fell to 13%, prompting an emergency C-section and a days-long ICU coma. Doctors placed an Impella heart pump to support her circulation, and she gradually recovered. Her EF normalized, but future pregnancies remain high-risk and require close monitoring; today she is healthy with her one-year-old son.

SPIRIT-HF Finds No Clear Benefit of Spironolactone in HFpEF/HFmrEF
heart-failure4 months ago

SPIRIT-HF Finds No Clear Benefit of Spironolactone in HFpEF/HFmrEF

SPIRIT-HF found no meaningful reduction in the primary endpoint (HF hospitalizations or cardiovascular death at 24 months) with spironolactone in patients with HFpEF or HFmrEF. The spironolactone group had more total hospitalizations and adverse events (hypotension, renal issues, hyperkalemia). A high COVID-19–related discontinuation and limited power may have muted efficacy signals; a meta-analysis with TOPCAT also showed no significant benefit, though ongoing registries may clarify safety and efficacy.

Every extra 1,000 mg of salt raises heart failure risk, study finds
health5 months ago

Every extra 1,000 mg of salt raises heart failure risk, study finds

A ten-year study of about 25,000 low-income Black and White adults in the southeastern US found that higher daily sodium intake increases heart‑failure risk; each extra 1,000 mg of sodium per day raises risk by ~8%, and participants averaging 4,200 mg/day had a 27% incidence of heart failure. Following guidelines of 2,300 mg/day (1,500 mg for hypertension) and reducing intake toward 4,000 mg/day could prevent ~6.6% of new heart‑failure cases over a decade, though the study relied on self-reported data and may not generalize to all populations.