Tag

Heart Failure

All articles tagged with #heart failure

SPIRIT-HF Finds No Clear Benefit of Spironolactone in HFpEF/HFmrEF
heart-failure12 days ago

SPIRIT-HF Finds No Clear Benefit of Spironolactone in HFpEF/HFmrEF

SPIRIT-HF found no meaningful reduction in the primary endpoint (HF hospitalizations or cardiovascular death at 24 months) with spironolactone in patients with HFpEF or HFmrEF. The spironolactone group had more total hospitalizations and adverse events (hypotension, renal issues, hyperkalemia). A high COVID-19–related discontinuation and limited power may have muted efficacy signals; a meta-analysis with TOPCAT also showed no significant benefit, though ongoing registries may clarify safety and efficacy.

Every extra 1,000 mg of salt raises heart failure risk, study finds
health14 days ago

Every extra 1,000 mg of salt raises heart failure risk, study finds

A ten-year study of about 25,000 low-income Black and White adults in the southeastern US found that higher daily sodium intake increases heart‑failure risk; each extra 1,000 mg of sodium per day raises risk by ~8%, and participants averaging 4,200 mg/day had a 27% incidence of heart failure. Following guidelines of 2,300 mg/day (1,500 mg for hypertension) and reducing intake toward 4,000 mg/day could prevent ~6.6% of new heart‑failure cases over a decade, though the study relied on self-reported data and may not generalize to all populations.

The Salt Line: 4,200 mg a Day Linked to Higher Heart Failure Risk
health15 days ago

The Salt Line: 4,200 mg a Day Linked to Higher Heart Failure Risk

A Vanderbilt-led study of 25,306 adults found that consuming about 4,200 mg of sodium daily—almost twice the recommended limit—was linked to a 15% higher risk of developing heart failure, with each additional 1,000 mg raising risk by 8% independent of other factors. Even modest reductions in average sodium could prevent a meaningful portion of new heart failure cases over 10 years (about 6.6% in the studied population), but most sodium comes from packaged foods, presenting challenges for lowering intake, especially in high-risk, low-resource communities; multilevel public health efforts will be needed.

Waist size outdoes BMI in predicting heart failure risk, study finds
health19 days ago

Waist size outdoes BMI in predicting heart failure risk, study finds

A Jackson Heart Study analysis found that waist circumference and waist-to-height ratio—measures of central obesity—predicted future heart failure risk, while BMI did not; higher systemic inflammation (hs-CRP) partially mediated this link (about 25–29%), suggesting fat distribution and inflammation drive risk; the study's limitations include a single-site African-American cohort and pending peer review; implications point to prioritizing central obesity and inflammation management through lifestyle changes to reduce heart failure risk.

Japan Approves First iPS-Cell Therapies for Heart Failure and Parkinson’s
science26 days ago

Japan Approves First iPS-Cell Therapies for Heart Failure and Parkinson’s

Japan’s health ministry conditionally approved two therapies derived from reprogrammed iPS cells—ReHeart for severe heart failure and Amusepri for Parkinson’s—marking the first medical treatments of this kind and signaling a new era in regenerative medicine, though extended safety and efficacy data from more patients are still needed.

Ray J's onstage blood moment fuels health controversy
entertainment-and-arts1 month ago

Ray J's onstage blood moment fuels health controversy

Ray J’s Shreveport performance featured a moment that appeared to show blood streaming from his eyes and a visible chest device, as he has said doctors told him his heart is failing with only months to live. Some observers believe the blood was a theatrical effect, while others note his health claims and eight prescribed medications. Doctors reportedly advised bed rest and avoiding alcohol, and Ray J has suggested he might need a pacemaker or defibrillator as heart damage from heavy substance use is cited.

Fatigue Mistaken for Aging Uncovered Rare Heart Condition in a Young Dad
health2 months ago

Fatigue Mistaken for Aging Uncovered Rare Heart Condition in a Young Dad

A Florida construction project manager in his early 30s blamed fatigue and weight gain on aging and new fatherhood, but after his symptoms worsened he was diagnosed with left ventricular non-compaction cardiomyopathy (LVNC) and a genetic muscle disorder, leading to advanced heart failure. He underwent a left ventricular assist device (LVAD) implantation to sustain circulation while awaiting a heart transplant, highlighting a rising trend of heart failure in younger adults driven by obesity, diabetes, and high blood pressure.

Chuck Negron, Frontman Behind Three Dog Night's Classic Hits, Dies at 83
entertainment2 months ago

Chuck Negron, Frontman Behind Three Dog Night's Classic Hits, Dies at 83

Chuck Negron, founding lead singer of Three Dog Night behind hits like 'Joy to the World' and 'One,' died at 83 in Studio City from complications of heart failure and COPD; once plagued by drug issues, he sobered in 1991 and later reconciled with bandmates. He is survived by his wife Ami Albea Negron and five children, including Berry Oakley Jr.

Stalled Progress in U.S. Heart Health: The Five Deadliest Diseases and Their Reach
health2 months ago

Stalled Progress in U.S. Heart Health: The Five Deadliest Diseases and Their Reach

A JACC study shows progress against U.S. heart disease has stalled as obesity and diabetes rise; the five deadliest conditions—coronary heart disease, heart attack, heart failure, peripheral artery disease, and stroke—continue to cause the most deaths and disability, driven by preventable risk factors such as hypertension, obesity, diabetes, high LDL cholesterol, and smoking.