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Copd

All articles tagged with #copd

AZ's tozorakimab delivers COPD benefit across populations in Phase 3
healthcare14 days ago

AZ's tozorakimab delivers COPD benefit across populations in Phase 3

AstraZeneca's anti-IL-33 antibody tozorakimab posted positive Phase 3 results in COPD (Oberon and Titania), reducing the annualized rate of moderate-to-severe exacerbations versus placebo in former smokers and showing benefit across the overall population, with a favorable safety profile. The drug’s supposed differentiation comes from complete inhibition of ST2 and RAGE/EGFR signaling, unlike rivals Roche and Sanofi/Regeneron’s IL-33 blockers that produced mixed results. AZ plans to present full data at an upcoming meeting and is pursuing two additional Phase 3 trials (Prospero, Miranda), while maintaining a target of potentially $3–5 billion in peak sales if approved.

via Fierce Biotech|
#astrazeneca#copd#healthcare
COPD relief hinges on one step: quitting smoking, says GP
health1 month ago

COPD relief hinges on one step: quitting smoking, says GP

GP Dr Philippa Kaye explains COPD is a chronic, incurable lung condition often linked to smoking; while not curable, symptoms can be markedly improved by quitting smoking (the single most important step), engaging in supervised exercise via a pulmonary rehabilitation program, using inhalers correctly, maintaining a healthy weight, and staying up to date with vaccines (flu, pneumococcal, RSV). Seek GP help if breathlessness or coughing worsens.

via Daily Mail|
#copd#health#inhalers
Chuck Negron, Frontman Behind Three Dog Night's Classic Hits, Dies at 83
entertainment2 months ago

Chuck Negron, Frontman Behind Three Dog Night's Classic Hits, Dies at 83

Chuck Negron, founding lead singer of Three Dog Night behind hits like 'Joy to the World' and 'One,' died at 83 in Studio City from complications of heart failure and COPD; once plagued by drug issues, he sobered in 1991 and later reconciled with bandmates. He is survived by his wife Ami Albea Negron and five children, including Berry Oakley Jr.

via Fox News|
#chuck-negron#copd#entertainment
Chuck Negron, Frontman of Three Dog Night, Dies at 83
obituaries2 months ago

Chuck Negron, Frontman of Three Dog Night, Dies at 83

Chuck Negron, founding member and lead vocalist of the LA rock band Three Dog Night, died at 83 in Studio City after battling COPD and heart failure. Born Charles Negron II in 1942 in the Bronx, he helped form Three Dog Night in 1967 with Danny Hutton and Cory Wells, delivering hits like Joy To The World and One. The group underwent lineup changes amid internal tensions and Negron’s struggles with addiction, though he later pursued a solo career and wrote an autobiography; he and Hutton reportedly reconciled last year. He is survived by his wife Ami Albea Negron and several children and relatives.

via Deadline|
#chuck-negron#copd#obituaries
Chuck Negron, Frontman Behind Three Dog Night’s Classic Hits, Dies at 83
entertainment2 months ago

Chuck Negron, Frontman Behind Three Dog Night’s Classic Hits, Dies at 83

Chuck Negron, a founding member and lead vocalist of Three Dog Night, died at 83 in Los Angeles from complications of heart failure and COPD. He powered a string of late-1960s/early-70s hits including Joy to the World, One and An Old Fashioned Love Song, and also sang Easy To Be Hard and The Show Must Go On. Negron battled drug issues during the band’s rise, spent time in rehab, and found sobriety in 1991, later pursuing a solo career and writing Three Dog Nightmare. After years of estrangement, he reconciled with fellow member Danny Hutton last year. He is survived by wife Ami Albea Negron and five children, including Berry Oakley Jr.,

via CBS News|
#chuck-negron#copd#entertainment
Chuck Negron, the Voice Behind Three Dog Night, Dies at 83
music2 months ago

Chuck Negron, the Voice Behind Three Dog Night, Dies at 83

Chuck Negron, co-founder and lead singer of Three Dog Night, died at 83 at his Studio City home after decades-long COPD; he helped the band reach peak fame with hits like One and Joy to the World but battled heroin addiction that led to years on Skid Row and multiple rehab stints as the group split in 1976, reformed in 1982, and finally broke up again in 1985; Negron later pursued a solo career and published a memoir, Cory Wells died in 2015, and Danny Hutton still tours with Three Dog Night, with Negron and Hutton reportedly burying the hatchet last year.

via Rolling Stone|
#chuck-negron#copd#joy-to-the-world
Chuck Negron, Three Dog Night’s Golden‑voiced Frontman, Dies at 83
obituaries2 months ago

Chuck Negron, Three Dog Night’s Golden‑voiced Frontman, Dies at 83

Chuck Negron, co‑founder and lead singer of Three Dog Night and the voice behind hits like Joy to the World and One, died at 83 at his Studio City home. The band chalked up 21 Top 40 hits and gold albums, but Negron battled heroin addiction and COPD for decades, pursued rehab in 1991, and ultimately reconciled with former bandmates. His legacy endures in the trio’s classic catalog and his later solo work.

via Variety|
#chuck-negron#copd#joy-to-the-world
Winded by Stairs? How to Tell Normal Breathlessness From a Health Red Flag
health2 months ago

Winded by Stairs? How to Tell Normal Breathlessness From a Health Red Flag

Feeling winded after climbing stairs can be a normal physiological response because stairs demand more oxygen and energy, but new or prolonged breathlessness warrants medical evaluation to rule out underlying conditions such as heart failure, obesity, COPD, or anemia. If recovery is quick, it’s usually not concerning; if breathing stays elevated for more than about three minutes or is accompanied by chest pain, headaches, or vision changes, consult a doctor. To improve stair endurance, gradually train and strengthen the muscles involved while addressing any medical issues first.

via HuffPost|
#breathlessness#copd#endurance-training
Younger People at Risk of Dangerous COPD
health7 months ago

Younger People at Risk of Dangerous COPD

A new study highlights that COPD can affect people under 50, with 4.5% of adults in this age group diagnosed, and that early onset COPD is linked to higher risks of hospitalization and death. Smoking remains the primary risk factor, but non-smokers can also develop COPD. Early diagnosis and lifestyle changes, including quitting smoking and vaccination, are crucial for managing the disease and improving outcomes.

via CNN|
#copd#health#lung-disease