Tag

Ipscs

All articles tagged with #ipscs

Lab-grown retinal vessels restore function in mice, fueling hope for blindness treatments
science14 days ago

Lab-grown retinal vessels restore function in mice, fueling hope for blindness treatments

Duke University researchers used induced pluripotent stem cells (iPSCs) to grow retinal endothelial cells—the vessels lining the retina—and demonstrated they can form functional vascular networks in lab conditions. When injected into mouse models of retinal disease, the lab-grown cells integrated with existing tissue to rebuild blood vessels and restore retinal function, suggesting a cheaper, scalable path toward preventative therapies for conditions like diabetic retinopathy.

Stem-derived retinal vessels repair damaged retinas in mice, paving way for new eye therapies
science19 days ago

Stem-derived retinal vessels repair damaged retinas in mice, paving way for new eye therapies

Duke researchers derived retinal endothelial cells from human iPSCs, generated lab-grown retinal vasculature, and showed these cells can integrate into diseased mouse retina to rebuild vessels and restore barrier function, offering a scalable model for studying eye diseases and a potential preventative therapy.