Tag

Mechanical Forces

All articles tagged with #mechanical forces

Beating Heart May Halt Cancer Growth, Spurring Mechanical Therapy
health1 month ago

Beating Heart May Halt Cancer Growth, Spurring Mechanical Therapy

A new study shows the mechanical force of heartbeats slows cancer growth by altering tumor cell gene activity. In mice and lab tissue, beating hearts reduced cancer proliferation and epigenetic markers linked to growth, with Nesprin-2 identified as a key sensor of heartbeat-induced forces. This points to potential mechanical therapies (like bands applying heartbeat-like force) or drugs that mimic the effect, though safety and timing must be established before human use.

Mechanical Forces and Evolutionary Strategies in Gastrulation and Organ Development
biology8 months ago

Mechanical Forces and Evolutionary Strategies in Gastrulation and Organ Development

The study reveals that the patterned invagination of the cephalic furrow in Drosophila prevents mechanical instability during gastrulation by absorbing compressive stresses caused by mitotic domains and germ band extension, with its formation regulated by specific gene expression patterns, and suggests that mechanical challenges have driven the evolution of this morphogenetic feature in dipteran flies.