Tag

Mortality

All articles tagged with #mortality

UK data link severe mental illness to decades of premature, preventable deaths
health17 days ago

UK data link severe mental illness to decades of premature, preventable deaths

UK NHS data cited by Rethink Mental Illness show adults under 75 with severe mental illness die about 15–20 years earlier than peers, largely from preventable physical diseases (liver, respiratory, cardiovascular diseases, cancer) and suicide. The gap is driven by poverty, housing, smoking, weight gain from medications, physical inactivity, and fragmented care, with 'diagnostic overshadowing' delaying investigation of physical symptoms. Advocates call for routine physical health checks and integrated, mental-health–informed care as government plans to act move forward.

New study raises mortality signal for cefepime in adults
health22 days ago

New study raises mortality signal for cefepime in adults

A global Bayesian meta-analysis of 110 randomized trials (over 22,000 patients) found cefepime, a broad-spectrum antibiotic, was associated with higher all-cause mortality than other beta-lactams (about 6.6% vs 6.2%), with the strongest signal in adults treated for febrile neutropenia. The study shows association, not proven causation, and potential explanations include dosing issues or neurotoxicity; researchers call for more guidance and research while not recommending stopping cefepime outright.

Dose matters: cefepime linked to higher death risk in adults, especially with febrile neutropenia
health23 days ago

Dose matters: cefepime linked to higher death risk in adults, especially with febrile neutropenia

A global meta-analysis of 110 randomized trials involving over 22,000 patients found that the antibiotic cefepime was associated with higher all-cause mortality than other beta-lactams, particularly among adults with febrile neutropenia. While the authors did not recommend stopping cefepime, they called for more guidance and research to clarify safety and optimal dosing, noting limitations such as study heterogeneity and proposing explanations like subtherapeutic or toxic drug levels and neurotoxicity; the dosing challenge may partly explain the observed association, and AI could help tailor dosing in the future.

New signal on cefepime safety: higher short-term death risk in adults tied to some usage patterns
health23 days ago

New signal on cefepime safety: higher short-term death risk in adults tied to some usage patterns

A global meta-analysis of 110 randomized trials (over 22,000 patients) found cefepime associated with higher all-cause mortality within about 30 days compared with other beta-lactam antibiotics, particularly in adults with febrile neutropenia; while not proving causation, potential factors include dosing challenges and neurotoxicity, prompting calls for clearer dosing guidance and further safety research rather than an outright discontinuation of cefepime.

Two Simple Walking Habits Slashed Death Risk, No 10,000 Steps Required
health23 days ago

Two Simple Walking Habits Slashed Death Risk, No 10,000 Steps Required

A study of 64,743 adults followed for about eight years found up to a 43% lower risk of death with two patterns: (1) fewer than 5,000 steps per day at a brisk pace, or (2) 5,000–7,500 steps per day at a slower pace. The long-rstanding 10,000-step goal is arbitrary, originating from a 1960s marketing campaign. Brisk walking is especially beneficial for those who sit a lot. The study is observational and based on one week of tracking, so it shows association, not causation. Practical takeaway: walk regularly and either increase pace or distance to reach moderate-intensity activity (~150 minutes per week).

Meta-analysis links cefepime to higher mortality; dosing guidance urged
health24 days ago

Meta-analysis links cefepime to higher mortality; dosing guidance urged

A Bayesian meta-analysis of 110 randomized trials (over 22,000 patients) found cefepime associated with higher all-cause mortality (778 deaths; 6.6%) versus other beta-lactams (6.2%), with a 94.4% probability—and 98.6% in the subset of 73 peer‑reviewed trials—that the drug raises risk. The association was stronger in adults and especially among febrile neutropenia patients. The researchers caution this shows association, not causation, and call for better dosing guidance and further study rather than an outright discontinuation of cefepime.

Autism Linked to 14-Year Life-Expectancy Gap, Flu as Primary Mortality Driver
health24 days ago

Autism Linked to 14-Year Life-Expectancy Gap, Flu as Primary Mortality Driver

A Medicaid-based study of people with autism spectrum disorder finds an average life expectancy of about 65 years—roughly 14 years shorter than the general population—driven mainly by influenza- and pneumonia-related deaths, with malnutrition, pneumonitis, non-vehicle accidents, and drowning also contributing. Although life expectancy for autistic individuals on Medicaid rose slightly from 2000–2019, the disparity remained and fell further in 2020 during the COVID-19 pandemic. The authors say better social support, primary care, and community-based services could close much of the mortality gap, though socioeconomic factors may bias estimates.

CDC shifts measles death counts amid Pennsylvania outbreak
health25 days ago

CDC shifts measles death counts amid Pennsylvania outbreak

Amid a Pennsylvania measles outbreak, the CDC switched its death tally from the National Notifiable Diseases Surveillance System to the National Center for Health Statistics data, a long-term mortality source not meant to confirm individual cases; Pennsylvania has two confirmed measles deaths this year and a third probable death linked to a measles infection with nasal-swab results pending, and officials warn the official count may understate fatalities while vaccination remains critical.

You Don't Need 10,000 Steps: Pace and Volume Together Lower Mortality
health25 days ago

You Don't Need 10,000 Steps: Pace and Volume Together Lower Mortality

New analysis of more than 64,000 middle-aged adults followed for about eight years shows that hitting 10,000 steps a day isn’t required to gain health benefits; mortality risk declined with various combinations of step count and intensity, including: under 5,000 steps with brisk pace (~80 steps/min) and 5,000–7,500 steps with slower pace (~60 steps/min) both reducing risk, while 7,500–10,000 steps per day also linked to the lowest mortality; a peak daily cadence of 90–100 steps/min during the day was identified as a sweet spot. The study emphasizes that longer-term, observational data can't prove causation and that there are potential confounders. The takeaway: combine volume and intensity, and those with barriers to higher steps or speed can still lower risk. Published in the British Journal of Sports Medicine.

Brisk walking beats the 10,000-step myth in lowering mortality risk
health26 days ago

Brisk walking beats the 10,000-step myth in lowering mortality risk

A large observational study of over 64,000 adults shows that walking pace during the day’s most active 30 minutes is linked to lower mortality, sometimes more strongly than reaching 10,000 steps. About 90–100 steps per minute (peak 30-minute cadence) was associated with lower death risk across step-count groups; even those with fewer than 5,000 steps benefited if walking faster. The findings challenge a universal 10,000-step goal and suggest tailoring activity to individual ability, while noting limitations like a short tracking period and potential wrist-count errors.

New Study Finds Covid Death Toll Was More Than Twice Official Counts Across Dozens of Countries
world29 days ago

New Study Finds Covid Death Toll Was More Than Twice Official Counts Across Dozens of Countries

A study analyzing all-cause mortality data from 134 countries finds that 45–55% undercounted Covid deaths in 2020–21, with actual deaths about 12.47 million versus 5.08 million officially recorded—suggesting widespread manipulation tied to weaker institutional checks and, in some cases, election timing; capacity limits also contributed to undercounting.

Speed Over Steps: Brisk Walking May Match High Step Counts for Longevity
health29 days ago

Speed Over Steps: Brisk Walking May Match High Step Counts for Longevity

A British Journal of Sports Medicine study of 103,684 UK Biobank participants shows walking pace can be as important as daily step totals for reducing all-cause and cardiovascular mortality. Those taking fewer than 5,000 steps per day but walking at 80+ steps per minute had similar risk to people exceeding 5,000 steps at a slower pace; overall, 7,500–10,000 daily steps corresponded to the lowest risk. The key message is behavioral flexibility: consistent movement and higher intensity when you walk can yield similar benefits to simply increasing step count, though the study is observational and cannot prove causation.

health1 month ago

Pace and steps together shape longevity risk, study finds

A UK Biobank analysis of 64,743 adults (40–69) shows both daily step count and walking pace influence mortality risk. The biggest reduction occurs with 7,500–10,000 steps per day regardless of pace, while brisk walking (about 90 steps per minute for at least 30 minutes daily) lowers death risk regardless of total steps. For sedentary people (<5,000 steps), increasing pace can substantially cut mortality risk, and slower walkers can benefit from more steps, suggesting flexible, pace-aware targets to reduce premature death risk.

Daily alcohol use linked to higher cancer deaths, new study finds
health1 month ago

Daily alcohol use linked to higher cancer deaths, new study finds

A Lancet study analyzing three decades of US data shows that alcohol substantially contributes to cancer deaths, with alcohol-related mortality rising about 58% from 1990 to 2023. The risk spans multiple cancers (including breast, liver, colorectal, stomach, pancreatic, and head/neck cancers), and even one standard drink per day can raise cancer risk. While overall cancer deaths have fallen, the share attributable to alcohol has increased, prompting calls to limit consumption; industry groups dispute a blanket “no safe level” claim. The study also notes age- and sex-specific differences, with younger adults and women showing higher relative risk at lower consumption levels. The bottom-line message: reducing alcohol intake to the lowest possible level is best for health.

One-drink-a-day risk: US cancer deaths rise sharply, study finds
health1 month ago

One-drink-a-day risk: US cancer deaths rise sharply, study finds

A new study of 30+ years of Global Burden of Disease data finds US alcohol-related cancer deaths more than doubled from 1990 to 2023, with even one daily drink increasing risk across multiple cancers (breast, prostate, colorectal, liver, etc.) and older men bearing the heaviest burden; alcohol is a known carcinogen, and low levels (about 5–15 g/day) can elevate risk, underscoring calls for consumer warnings.