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Nih Funding

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Massachusetts Biotech Boom Delivers VC Cash, But Workforce Shrinks
business5 hours ago

Massachusetts Biotech Boom Delivers VC Cash, But Workforce Shrinks

Massachusetts’ biotech scene shows a mixed picture: venture capital funding in H1 2026 totaled $3.45B (up 25% YoY) with Cambridge and Boston leading deals and eight IPOs signaling a strong exit environment, while NIH funding remains a bright spot per capita (Massachusetts at 9.3% of NIH funding and $477 per person) even as total NIH awards fell 6.2%. Early-stage financing looks mixed: seed rounds rose (15→21) but average raises dropped from $7.6M to $4.6M. Biopharma R&D jobs fell about 3,600 in 2025 (3.1%), though there was a late-year rebound and strong pipeline metrics—Massachusetts accounts for a large share of U.S. VC, the drug-development pipeline, and possess abundant lab space (63.2M sq ft with 31% vacancy) that could help fuel a rebound if capital returns to early-stage companies and policy supports competitiveness without unduly limiting China investments.

via Fierce Biotech|
#biotech#business#ipos
ADA faces backlash after expulsion of dissenting doctors at conference
health2 months ago

ADA faces backlash after expulsion of dissenting doctors at conference

Five doctors distributing an editorial criticizing federal NIH funding cuts were escorted out of the ADA conference in New Orleans, triggering widespread outrage among researchers and leading to resignations by top ADA leaders; the organization defended the action as enforcing conduct rules, but critics warn it harms scientific integrity and open debate amid funding pressures.

via statnews.com|
#ada#diabetes#health
NIH-backed STEP brain-delivery tech raises questions about brain gene editing
science2 months ago

NIH-backed STEP brain-delivery tech raises questions about brain gene editing

Yale researchers secured a $40M NIH grant to advance STEP, a 10-nm brain-delivery platform for CRISPR gene editors; early preclinical work in mice hints at brain-wide delivery and functional gains, but the mechanism remains unclear, safety and scaling concerns persist, and full details won’t be published until 2028 as clinical work progresses.

via The Transmitter|
#angelman-syndrome#brain-delivery#gene-editing
NIH Bets Big on Human-Based Research to Cut Animal Testing
science5 months ago

NIH Bets Big on Human-Based Research to Cut Animal Testing

NIH is investing over $150 million to advance human-based research methods (NAMs) and reduce animal testing, creating technology development centers, a NAMs data hub, and a validation network; four pilot NAMs projects on preterm birth, developmental neurotoxicity, inhalation toxicity, and acute oral toxicity will be funded, with a separate $7 million Reduction to Practice Challenge with FDA and EPA to push NAMs toward regulatory use.

via National Institutes of Health (.gov)|
#animal-model-reduction#complement-arie#nams
AI-drafted grants edge NIH funding but risk dampening novelty
science-policy6 months ago

AI-drafted grants edge NIH funding but risk dampening novelty

AI-assisted NIH grant proposals appear about 4% more likely to be funded and yield more papers, but they tend to resemble prior work, raising concerns about reduced novelty and potential homogeneity; NSF proposals show no funding advantage from AI use. Findings come from an arXiv preprint analyzing NIH/NSF submissions and AI-rewritten abstracts, and are not yet peer reviewed.

via Nature|
#ai#arxiv#grant-writing
Hope on Hold: DIPG Families Fight for Trials Amid U.S. Funding Cuts
health7 months ago

Hope on Hold: DIPG Families Fight for Trials Amid U.S. Funding Cuts

A Guardian feature follows Izzy, a four-year-old with diffuse intrinsic pontine glioma (DIPG), and the families and doctors racing to find experimental treatments as the Trump era’s funding cuts cripple NIH support, shutter the Pediatric Brain Tumor Consortium, and suspend or delay dozens of clinical trials. The result is that progress in DIPG research stalls just as families face a last-hope window, turning access to new therapies into a bureaucratic and political obstacle. In the end, Izzy receives a reprieve when Stanford offers a CAR-T cell trial, a glimmer of hope amid a landscape of lost trials and dwindling resources.

via The Guardian|
#clinical-trials#dipg#health
Scientists Launch $14.2 Million Project to Map the Human Sixth Sense
science10 months ago

Scientists Launch $14.2 Million Project to Map the Human Sixth Sense

Scientists from Scripps Research and the Allen Institute, led by Nobel laureate Ardem Patapoutian, received $14.2 million from the NIH to create the first comprehensive map of interoception, the body's internal sensory system, aiming to better understand how the brain monitors internal signals and its implications for health and disease.

via Science Daily|
#atlas#brain-body-connection#interoception
"Controversy Surrounds US Government-Funded Bat Research Labs"
science-and-research2 years ago

"Controversy Surrounds US Government-Funded Bat Research Labs"

A new taxpayer-funded lab is being built in Colorado that will import bats from around the world and experiment on dangerous diseases, including Ebola, Nipah virus, and Covid-19. The collaboration between the National Institutes of Health (NIH), Colorado State University (CSU), and EcoHealth Alliance (EHA) has raised concerns among Republican Senators who fear the facility could start a pandemic on US soil. The lab, due to open in 2025, has faced opposition from Fort Collins residents who worry about the potential spread of diseases. The project has been criticized for its controversial collaboration with EHA, which has been linked to the Covid lab leak theory.

via Daily Mail|
#bat-research#biosafety#controversial-collaboration