Tag

Riluzole

All articles tagged with #riluzole

Market-Ready Meds Could Slow Dementia, Panel Finds
health1 month ago

Market-Ready Meds Could Slow Dementia, Panel Finds

An international expert panel identifies eight drugs already on the market as candidates for further study to prevent or slow dementia. The shingles vaccine shows the strongest real‑world signal, with Welsh data suggesting about a 20% reduction in dementia risk among recipients; the newer Shingrix vaccine is anticipated to be at least as effective. Other drugs cited include Viagra (sildenafil), riluzole, Gilenya (fingolimod), and vortioxetine, though evidence for these is less clear and confounded by factors such as lifestyle and relationships. The panel emphasizes more rigorous research and potential trials to determine true benefits at the population level.

"Intrathecal Delivery of Riluzole: A Clear Efficacy in ALS Therapy"
health2 years ago

"Intrathecal Delivery of Riluzole: A Clear Efficacy in ALS Therapy"

Brain Trust Bio has been approved to conduct Phase 1 clinical trials in Australia to test the efficacy of its intrathecal delivery method for ALS therapy riluzole, which aims to enhance therapeutic benefits while minimizing side effects. The approach involves directly infusing medication into the spinal canal to bypass the blood brain barrier and access the central nervous system. Early signs suggest that this method may be more effective than existing delivery modes, potentially extending survival by a year or more. The company also plans to evaluate its delivery method in multiple sclerosis and spinal cord cancer.