Tag

Tuberculosis

All articles tagged with #tuberculosis

WHO 2026: Post-2030 TB strategy takes shape as SLD and bleeding disorders gain policy traction
health10 days ago

WHO 2026: Post-2030 TB strategy takes shape as SLD and bleeding disorders gain policy traction

At the Seventy-ninth World Health Assembly, delegates endorsed developing a post-2030 TB strategy for 2028 and reviewed progress and challenges of the End TB Strategy, noting funding gaps. The Assembly also approved recognizing steatotic liver disease as a growing NCD burden and urged its integration into national plans, while backing stronger care for haemophilia and other bleeding disorders. A strategic roundtable on health mis- and disinformation highlighted the need for multisectoral action and trusted information to safeguard public health.

California Faces Record TB Outbreaks as Rates Surpass U.S. Average
health22 days ago

California Faces Record TB Outbreaks as Rates Surpass U.S. Average

California posted a record 2,150+ TB cases in 2025 with a rate of 5.4 per 100,000—nearly double the national rate. A CDC/MMWR review found about 50 large TB outbreaks from 2017–2023, many linked to family/social networks or congregate settings and associated with factors like housing insecurity and substance use. The Bay Area saw outbreak testing at Archbishop Riordan High School, and experts say preventing outbreaks will require stronger genomic surveillance, better TB programs, and addressing homelessness and related social determinants of health.

TB exposure alerts hit California schools as infections rise
health1 month ago

TB exposure alerts hit California schools as infections rise

California health officials confirmed tuberculosis exposure at Justin Garza High School with one active infection and 22 of 169 exposed testing positive but asymptomatic; a possible exposure was also reported at Sunset Elementary in San Ysidro. No students or staff are currently contagious on campus, and investigators are conducting contact tracing and free screenings. San Diego County TB cases have risen from 193 in 2020 to 265 in 2025, highlighting a rising trend in the state.

MDR-TB exposure warning issued for Southwestern College campus
health1 month ago

MDR-TB exposure warning issued for Southwestern College campus

Southwestern College in Chula Vista, California notified students that they may have been exposed to multidrug-resistant tuberculosis at its main campus between Oct. 27 and Dec. 14, 2025. MDR-TB is harder to treat and may require longer exposure periods; county health officials are advising immediate screening, with free on-campus TB screenings offered to those identified as having been directly exposed as the college cooperates with the investigation.

Johns Hopkins Develops Nasal DNA Vaccine to Augment TB Treatment
science1 month ago

Johns Hopkins Develops Nasal DNA Vaccine to Augment TB Treatment

Johns Hopkins Medicine researchers have created a therapeutic, intranasal DNA vaccine against tuberculosis by fusing RelMtb with Mip3α. When used with standard TB drug therapy, it strengthened lung and systemic immunity, sped bacterial clearance, reduced lung inflammation, and prevented relapse in mice, with durable immune responses observed in nonhuman primates, suggesting a path toward human trials and the potential to shorten TB treatment, including for drug-resistant strains.

Massive TB exposure traced to Sheba Medical Center prompts health response
health2 months ago

Massive TB exposure traced to Sheba Medical Center prompts health response

A pulmonary TB patient stayed in Sheba Medical Center's underground surgical unit (March 17–22, 2026), exposing about 750 patients (including around 300 newborns) and roughly 1,900 staff, plus unknown visitors. Health authorities and Sheba launched an epidemiological investigation; exposed individuals will receive Mantoux skin tests, with preventive antibiotics for positives. Infants under age 3 and immunocompromised people will begin four months of antibiotics immediately. Visitors with more than eight hours of exposure are advised to contact the Health Ministry hotline. TB is airborne, with higher risk after prolonged exposure, and the situation will be monitored and updated.

U.S. TB Cases Climb as Latent Infections Reactivate Post-Pandemic
health2 months ago

U.S. TB Cases Climb as Latent Infections Reactivate Post-Pandemic

Tuberculosis, known as the white plague, is rising in the United States after COVID-19 disrupted screening and treatment, with 2024 TB cases topping 10,600—the highest since 2013. Health officials say many infections are latent and undiagnosed, reactivating as screenings resume and international travel/migration rebounds. About 25% of people are infected with TB, but 5%–10% progress to active disease. TB is curable with antibiotics, but incomplete treatment risks drug resistance; higher-risk groups include people born in or traveling to TB-burden countries, those living in crowded conditions, and immunocompromised individuals. Emphasis is on testing and treating latent TB to prevent progression to active disease.

Tuberculosis Stages a Modern Comeback in the U.S., Raising Drug-Resistance Fears
health2 months ago

Tuberculosis Stages a Modern Comeback in the U.S., Raising Drug-Resistance Fears

TB is resurging in the United States, with provisional 2025 data showing 10,260 cases nationwide (967 in New York). The disease often exists as latent infections (up to 13 million nationwide) that can activate, fueling spread and antibiotic resistance (589 cases resistant to at least one frontline drug in 2023). Active and latent TB require long antibiotic regimens (6–9 months), and early detection plus vaccination considerations are key to prevention. Globally TB remains one of the deadliest infectious diseases, underscoring the ongoing public-health challenge in America and beyond.

New TB Antibiotics Target Bacteria’s Protein Recycling, Offering Hope Against Drug-Resistant TB
science2 months ago

New TB Antibiotics Target Bacteria’s Protein Recycling, Offering Hope Against Drug-Resistant TB

Researchers analyzed three experimental anti-TB compounds—ecumicin, ilamycins, and cyclomarins—and found they all disrupt the M. tuberculosis protein-recycling machine ClpC1-ClpP1P2, each in a different way, causing widespread disturbances across thousands of bacterial proteins and triggering stress responses (ecumicin notably raises Hsp20). This mechanistic mapping provides a clearer path to designing more precise anti-TB drugs as drug-resistant TB remains a major global threat; the work was published in Nature Communications.

WHO backs near-point-of-care TB tests and tongue swabs to speed diagnosis
health2 months ago

WHO backs near-point-of-care TB tests and tongue swabs to speed diagnosis

WHO endorses portable, near-point-of-care TB tests that are battery-powered and deliver results in under an hour, plus tongue-swab sampling and sputum pooling to expand testing, cut costs, and start treatment sooner; the guidance, released for World TB Day 2026, calls for urgent scale-up and sustained investment as funding gaps threaten progress, with potential benefits for testing other diseases as well.

Tuberculosis makes a quiet comeback in the United States
health2 months ago

Tuberculosis makes a quiet comeback in the United States

Vox’s Future Perfect reports that tuberculosis is rising in the United States as latent infections awaken into active disease, with outbreaks surfacing in places like Archbishop Riordan High School in San Francisco, Long Island, and Seattle. The piece argues that TB remains a global health threat and that domestic progress depends on a strong public-health infrastructure, timely diagnosis, access to preventive therapy, and sustained funding for research and treatment. Delays, drug shortages, and the high cost of care threaten prevention and risk more outbreaks and drug resistance, underscoring the need for new diagnostics, vaccines, and policy action to curb TB at home and worldwide.

No Additional Tuberculosis Cases Linked to Patchogue-Medford HS as Suffolk Health Investigates
health3 months ago

No Additional Tuberculosis Cases Linked to Patchogue-Medford HS as Suffolk Health Investigates

Suffolk County health officials say one active tuberculosis case has been identified in the Patchogue-Medford High School community; the investigation is ongoing, with free testing offered to potentially exposed individuals and tests conducted at the high school on Jan. 28 and 30, with a follow-up in March after the two‑month incubation period. No additional cases have been identified and privacy protections are in place.