Tag

Adiposity

All articles tagged with #adiposity

science25 days ago•34 min saved

Fat and cancer: decoding mechanisms and a path to prevention

This Nature Metabolism review summarizes how excess adiposity is a major modifiable risk factor for at least 19 cancer types, detailing mechanisms involving sex hormones, hyperinsulinaemia, and chronic inflammation, and integrating omics insights with tumor-subtype associations; it also outlines priorities for future research—imaging-based adiposity measures, multi-omics integration, and data from underrepresented populations—while considering how obesity therapies (e.g., GLP-1 receptor agonists, weight loss) might transform cancer prevention at scale.

via Nature|

#adiposity #cancer #epidemiology

science1 month ago•24 min saved

Hidden fat spots may speed up brain aging, study shows

A large UK Biobank analysis of over 18,000 middle-aged and older adults finds that fat distribution—arm, leg, trunk, and especially visceral fat around internal organs—independently shapes brain structure, connectivity, and cognitive performance beyond BMI. Arm and trunk fat are linked to sensorimotor cortex thinning and hippocampal volume loss; leg fat affects limbic networks; visceral fat shows the strongest association with white-matter deterioration and faster brain aging as estimated by a Brain Age model. These patterns persist after adjusting for BMI, but the cross-sectional design means causality cannot be established.

via PsyPost|

#adiposity #brain-aging #cognitive-function

science5 months ago•19 min saved

No universal testosterone: culture and ecology reshape our hormonal norms

A study of 104 Shuar men in Amazonian Ecuador finds that Western notions of a single “normal” testosterone pattern don’t apply globally. Morning testosterone levels were lower than in the US and declined across the day, with age and body fat producing different lifespan patterns: lean men show an inverted U with a midlife peak, while higher-fat men peak earlier and then decline. Social factors also matter, as men with partners had lower morning levels. The results challenge universal clinical benchmarks and highlight energy, environment, and lifestyle as drivers of hormonal regulation, though the cross-sectional design limits causal conclusions.

via PsyPost|

#adiposity #aging #anthropology

science8 months ago•3 min saved

Women Can Gauge Age, Body Fat, and Testosterone from Men's Faces

A Polish study found that women perceive men with lower body fat as more attractive, and facial masculinity correlates with higher testosterone and age. While initial links between facial appearance and health markers like cardiometabolic health were observed, these were explained by broader factors such as adiposity, age, and testosterone levels, suggesting facial cues reflect overall biological condition rather than specific health issues.

via PsyPost|

#adiposity #biomarkers #facial-attractiveness

health2 years ago•4 min saved

Study Confirms BMI Effective for Assessing Kids' Body Fat

A study published in Pediatrics found that children and teens with high BMI are 29 times more likely to have high fat mass, suggesting BMI is a useful screening tool for adiposity despite its limitations. The study supports the continued use of BMI in pediatrics, emphasizing a person-centered approach for assessing health outcomes.

via Ars Technica|

#adiposity #bmi #body-composition