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Charleston Gains Access to Breakthrough KRAS Pancreatic Cancer Drug
health2 days ago

Charleston Gains Access to Breakthrough KRAS Pancreatic Cancer Drug

Charleston-area patients with metastatic pancreatic cancer are receiving daraxonrasib, a KRAS-targeted drug that showed in Phase 3 trials to roughly double median survival (about 13.2 months versus 6.6 with chemotherapy) via an expanded-access program before FDA approval. Terri Truere became the first local patient treated at Roper St. Francis Cancer Center, a development clinicians say could improve targeting of the KRAS mutation and potentially expand surgical options, though the drug carries notable side effects such as mouth sores, sore throat and rash. The rollout offers optimism for pancreatic cancer treatment and for next-generation KRAS therapies.

via Post and Courier|
#charleston#daraxonrasib#expanded-access
KRAS-targeting pancreatic cancer drug boosts survival, reaches Charleston patients
health3 days ago

KRAS-targeting pancreatic cancer drug boosts survival, reaches Charleston patients

A Phase 3 trial showed daraxonrasib, a KRAS-targeting therapy for metastatic pancreatic cancer, nearly doubles median survival (about 13.2 months vs 6.6) and is moving into expanded-access programs, with Terri Truere in Charleston among the first patients in the area to receive it ahead of FDA approval. The drug is not yet approved, but more SC sites are preparing to offer it; it carries notable side effects such as mouth sores and rash, and access remains limited. Doctors see promise that KRAS targeting could improve outcomes and potentially expand surgical eligibility in some patients.

via Yahoo|
#charleston#daraxonrasib#expanded-access
Stunning New Image Shows Coral Reef Near Charleston
environment10 months ago

Stunning New Image Shows Coral Reef Near Charleston

A stunning new image captured by marine biologist Phil Dustan reveals a vibrant coral reef thriving around the wreck of the Frederick W. Day schooner, located 11 miles off Charleston. The wreck, which sank in 1914, has become an artificial reef supporting diverse tropical marine life, but overfishing threatens its ecosystem. Dustan and diver Tom Robinson advocate for marine protected areas to preserve this unique underwater habitat, highlighting its ecological and climate significance.

via Post and Courier|
#charleston#conservation#coral-reef
Boeing Announces Nationwide Layoffs Impacting Thousands
business1 year ago

Boeing Announces Nationwide Layoffs Impacting Thousands

Boeing plans to lay off 10% of its workforce, affecting nearly 17,000 employees, including over 200 in Charleston, as part of a broader workforce reduction strategy. The layoffs, set for January 2025, are part of Boeing's efforts to align with financial realities and focus on critical business priorities. The company has faced financial difficulties since the 737 Max crashes and a recent strike, though the layoffs are attributed to overstaffing. Affected employees will receive severance and support services.

via WCBD News 2|
#boeing#business#charleston
"Runaway Cargo Ship Forces Temporary Closure of Charleston's Ravenel Bridge"
transportation-incident2 years ago

"Runaway Cargo Ship Forces Temporary Closure of Charleston's Ravenel Bridge"

A large cargo ship, MSC Michigan 7, temporarily lost propulsion and forced the closure of the Arthur Ravenel Jr. Bridge in Charleston, South Carolina. The US Coast Guard and local authorities managed to avert disaster by clearing the bridge and surrounding areas. The ship eventually regained control and anchored offshore, causing minor injuries and damage along its route. The incident highlights ongoing concerns about aging infrastructure and the increasing size of cargo vessels.

via CNN|
#bridge-closure#cargo-ship#charleston
Trader Joe’s Expands to Mount Pleasant
business2 years ago

Trader Joe’s Expands to Mount Pleasant

Trader Joe's is opening its second Charleston-area store at Sweetgrass Corner, located at 1909 North Highway 17. The new store will occupy part of a former BI-LO grocery store, with the remaining space to be leased by other tenants. The Continental Realty Corporation, which owns the space, believes the new store will benefit the surrounding community. No timeline or projected opening date has been announced yet.

via Live 5 News WCSC|
#business#charleston#community-impact